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Open AccessCommunication

Achieving Health Security and Threat Reduction through Sharing Sequence Data

MRIGlobal, Gaithersburg, MD 20878, USA
Los Alamos National Laboratory, Los Alamos, NM 87545, USA
Defense Threat Reduction Agency, Fort Belvoir, VA 22060, USA
National Center for Disease Control and Public Health, Tbilisi 0198, Georgia
Department of State, Washington, DC 20520, USA
USAID, Bureau of Global Health, Arlington, VA 22202, USA
Department of Epidemiology, Columbia University, Mailman School of Public Health, New York, NY 10032, USA
One Health Institute, University of California, Davis, CA 95616, USA
National Institute for Microbial Forensics & Food and Agricultural Biosecurity, Oklahoma State University, Stillwater, OK 74078, USA
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(2), 78;
Received: 14 April 2019 / Revised: 4 May 2019 / Accepted: 8 May 2019 / Published: 14 May 2019
(This article belongs to the Special Issue Globalization and Infectious Diseases)
With the rapid development and broad applications of next-generation sequencing platforms and bioinformatic analytical tools, genomics has become a popular area for biosurveillance and international scientific collaboration. Governments from countries including the United States (US), Canada, Germany, and the United Kingdom have leveraged these advancements to support international cooperative programs that aim to reduce biological threats and build scientific capacity worldwide. A recent conference panel addressed the impacts of the enhancement of genomic sequencing capabilities through three major US bioengagement programs on international scientific engagement and biosecurity risk reduction. The panel contrasted the risks and benefits of supporting the enhancement of genomic sequencing capabilities through international scientific engagement to achieve biological threat reduction and global health security. The lower costs and new bioinformatic tools available have led to the greater application of sequencing to biosurveillance. Strengthening sequencing capabilities globally for the diagnosis and detection of infectious diseases through mutual collaborations has a high return on investment for increasing global health security. International collaborations based on genomics and shared sequence data can build and leverage scientific networks and improve the timeliness and accuracy of disease surveillance reporting needed to identify and mitigate infectious disease outbreaks and comply with international norms. Further efforts to promote scientific transparency within international collaboration will improve trust, reduce threats, and promote global health security. View Full-Text
Keywords: biosecurity; global health security; sequencing; scientific engagement; threat reduction biosecurity; global health security; sequencing; scientific engagement; threat reduction
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Yeh, K.; Fair, J.; Cui, H.; Newman, C.; Braunstein, G.; Chanturia, G.; Vora, S.; Chittenden, K.; Tseng, A.; Monagin, C.; Fletcher, J. Achieving Health Security and Threat Reduction through Sharing Sequence Data. Trop. Med. Infect. Dis. 2019, 4, 78.

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