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Correction: Sando E. et al. Serological Cross-Reactivity among Orientia tsutsugamushi Serotypes but Not with Rickettsia japonica in Japan. Trop. Med. Infect. Dis. 2018, 3, 74.
Open AccessCase Report

Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate

1
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
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Infectious Diseases Unit, Department of Internal Medicine, Universiti Teknologi MARA, Sungai Buloh 47000, Malaysia
3
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
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Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
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Department of Medicine, Swiss Tropical and Public Health Institute, 4056 Basel, Switzerland
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Faculty of Medicine, University of Basel, 4003 Basel, Switzerland
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Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Churchill Hospital, Oxford OX3 7FZ, UK
*
Authors to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2019, 4(1), 23; https://doi.org/10.3390/tropicalmed4010023
Received: 11 November 2018 / Revised: 28 January 2019 / Accepted: 30 January 2019 / Published: 31 January 2019
(This article belongs to the Special Issue The Past and Present Threat of Rickettsial Diseases)
Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia. View Full-Text
Keywords: murine typhus; diagnosis; serology; Malaysia murine typhus; diagnosis; serology; Malaysia
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Yuhana, Y.; Tanganuchitcharnchai, A.; Sujariyakul, P.; Sonthayanon, P.; Chotivanich, K.; Paris, D.H.; Pukrittayakamee, S.; Blacksell, S.D.; Hanboonkunupakarn, B. Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate. Trop. Med. Infect. Dis. 2019, 4, 23.

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