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Open AccessCase Report

Salmonella enterica Serovar Typhi: An Unusual Cause of Infective Endocarditis

Department of Infectious Diseases, Blacktown Hospital, Blacktown, NSW 2148, Australia
Centre for Infectious Diseases and Microbiology, Westmead Hospital, Westmead, NSW 2145, Australia
Marie Bashir Institute for Infectious Diseases and Biosecurity, University of Sydney, Westmead, NSW 2145, Australia
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2018, 3(1), 35;
Received: 11 February 2018 / Revised: 12 March 2018 / Accepted: 14 March 2018 / Published: 16 March 2018
PDF [202 KB, uploaded 3 May 2018]


While typhoid fever is a common infection, Salmonella enterica serovar Typhi is a rare cause of endocarditis. We describe the case of a 20-year-old male who was treated for a primary episode of microbiologically-confirmed typhoid fever. He presented six weeks post-discharge with fever and lethargy. S. Typhi was again identified in blood cultures, and echocardiography identified a mitral valve lesion. Our case suggests that a relapse of typhoid should prompt further investigation for a deep-seated infection, including consideration of echocardiographic evaluation to rule out infective endocarditis. View Full-Text
Keywords: Salmonella Typhi; infective endocarditis; relapse; mitral valve Salmonella Typhi; infective endocarditis; relapse; mitral valve
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Robson, C.; O’Sullivan, M.V.N.; Sivagnanam, S. Salmonella enterica Serovar Typhi: An Unusual Cause of Infective Endocarditis. Trop. Med. Infect. Dis. 2018, 3, 35.

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