Vision and Hyper-Responsiveness in Migraine
Abstract
:1. Introduction
2. Experiment 1: Contrast Discrimination
1.1. Participants
1.2. Procedure
3. Results
4. Experiment 2: Comfortable Chromaticity
4.1. Participants
4.2. Procedure
5. Results
6. Experiment 3: Contrast Discrimination and the Effects of Colour
6.1. Participants
6.2. Procedure
7. Results
8. Discussion
- (1)
- Those for whom colour is of no benefit choose light of familiar colours to which they are habitually exposed. Perhaps those patients who are most likely to benefit from tinted lenses choose colours away from the Planckian locus,
- (2)
- Individuals with migraine are rarely exposed to light of a colour they find comfortable, which may have consequences for photophobia. Noseda et al. [24] have proposed a role for the intrinsically photosensitive retinal ganglion cells (ipRGC) in photophobia. The cells are not themselves sensitive to patterns of the kind used here, but the ipRGC cells may indirectly contribute to contrast sensitivity [25]. The ipRGC are melanopic, with the spectral sensitivity being greatest at short wavelengths. The distribution of selected chromaticities shows no preference for short-wavelength light.
Supplementary Materials
Author Contributions
Funding
Conflicts of Interest
References
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Group | Mean | SD |
---|---|---|
Control | 0.00107 | (0.00158) |
MO | 0.00129 | (0.00114) |
MA | 0.00265 | (0.00256) |
Affected Field Coloured Lens | Unaffected Field Grey Lens | |
---|---|---|
Unaffected field Coloured lens | p = 0.212 | p = 0.001 |
Affected field | p = 0.001 | p = 0.267 |
Grey lens |
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Aldrich, A.; Hibbard, P.; Wilkins, A. Vision and Hyper-Responsiveness in Migraine. Vision 2019, 3, 62. https://doi.org/10.3390/vision3040062
Aldrich A, Hibbard P, Wilkins A. Vision and Hyper-Responsiveness in Migraine. Vision. 2019; 3(4):62. https://doi.org/10.3390/vision3040062
Chicago/Turabian StyleAldrich, Amelia, Paul Hibbard, and Arnold Wilkins. 2019. "Vision and Hyper-Responsiveness in Migraine" Vision 3, no. 4: 62. https://doi.org/10.3390/vision3040062