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10.3390/vision2010015
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Review

New Therapies of Neovascular AMD beyond Anti-VEGF Injections

by
Greggory M. Gahn
1 and
Arshad M. Khanani
2,*
1
University of Nevada, Reno School of Medicine, Reno, NV 89557, USA
2
Sierra Eye Associates, Reno, NV 89502, USA
*
Author to whom correspondence should be addressed.
Vision 2018, 2(1), 15; https://doi.org/10.3390/vision2010015
Submission received: 22 January 2018 / Revised: 4 February 2018 / Accepted: 12 March 2018 / Published: 19 March 2018
(This article belongs to the Special Issue Age-Related Macular Degeneration)
Versions Notes

Abstract

Neovascular age-related macular degeneration is a leading cause of vision loss among the aging population. The current standard of care to treat neovascular age-related macular degeneration is inhibiting vascular endothelial growth factor (VEGF) through intravitreal injections. Recent studies have demonstrated that the tyrosine kinase with immunoglobulin-like and epidermal growth factor-like domains 2 (Tie2) pathway also plays a critical role in angiogenesis and vascular stability. Additionally, newly developed treatment delivery systems have been designed to greatly reduce the frequency of injections. In targeting the Tie2 pathway and utilizing a sustained release delivery system, patients may experience improved visual outcomes and a reduced burden of treatment.
Keywords: age-related macular degeneration; Tie2; anti-VEGF; RG7716; ranibizumab age-related macular degeneration; Tie2; anti-VEGF; RG7716; ranibizumab

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MDPI and ACS Style

Gahn, G.M.; Khanani, A.M. New Therapies of Neovascular AMD beyond Anti-VEGF Injections. Vision 2018, 2, 15. https://doi.org/10.3390/vision2010015

AMA Style

Gahn GM, Khanani AM. New Therapies of Neovascular AMD beyond Anti-VEGF Injections. Vision. 2018; 2(1):15. https://doi.org/10.3390/vision2010015

Chicago/Turabian Style

Gahn, Greggory M., and Arshad M. Khanani. 2018. "New Therapies of Neovascular AMD beyond Anti-VEGF Injections" Vision 2, no. 1: 15. https://doi.org/10.3390/vision2010015

APA Style

Gahn, G. M., & Khanani, A. M. (2018). New Therapies of Neovascular AMD beyond Anti-VEGF Injections. Vision, 2(1), 15. https://doi.org/10.3390/vision2010015

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