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Safety 2017, 3(4), 25;

Microneedle Manufacture: Assessing Hazards and Control Measures

School of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UK
Author to whom correspondence should be addressed.
Academic Editor: Raphael Grzebieta
Received: 21 March 2017 / Revised: 3 July 2017 / Accepted: 24 October 2017 / Published: 30 October 2017
PDF [3238 KB, uploaded 30 October 2017]


Transdermal microneedles have captured the attention of researchers in relation to a variety of applications, and silicone-based moulds required to produce these systems are now widely available and can be readily manufactured on the lab bench. There is however some concern over the potential for accidental needlestick injuries and, as with any sharp hazard, the potential for blood-borne pathogen transmission must be considered. This follows from recent governmental concerns over the use of microneedle systems in dermabrasion. Despite the piercing nature of the microneedle patch sharing many similarities with conventional hypodermic needles, there are notable factors that mitigate the risk of contamination. A range of microneedle systems has been prepared using micromoulding techniques, and their puncture capability assessed. A critical assessment of the potential for accidental puncture and the control measures needed to ensure safe utilisation of the patch systems is presented. View Full-Text
Keywords: microneedle; transdermal; smart patches; needlestick; pathogen microneedle; transdermal; smart patches; needlestick; pathogen

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Martin, A.; McConville, A.; Anderson, A.; McLister, A.; Davis, J. Microneedle Manufacture: Assessing Hazards and Control Measures. Safety 2017, 3, 25.

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