Deciphering the Molecular Mechanism of Incurable Muscle Disease by a Novel Method for the Interpretation of miRNA Dysregulation
Abstract
:1. MicroRNA Dysregulation in Human Diseases
2. Problems and Weaknesses of Biological Interpretations of miRNA Dysregulation Using the Target Gene Method
3. Development of a Complementary Method for the Interpretation of miRNA Dysregulation
4. Interpretation of miRNA Dysregulation in DMD Using the Target Gene Method
5. Interrelations between miRNAs and Their Host Genes
6. Co-Dysregulation of miRNA and Host Genes in DMD
7. miRNAs and Their Host Genes May Coordinately Regulate Disease State in DMD
8. Interpretation of miRNA Dysregulation in DMD Using the Host Gene Method
9. Target Genes versus Host Genes for the Interpretation of miRNA Dysregulation
10. Experimental Validation in DMD
11. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Israeli, D.; Vu Hong, A.; Corre, G.; Miagoux, Q.; Richard, I. Deciphering the Molecular Mechanism of Incurable Muscle Disease by a Novel Method for the Interpretation of miRNA Dysregulation. Non-Coding RNA 2022, 8, 48. https://doi.org/10.3390/ncrna8040048
Israeli D, Vu Hong A, Corre G, Miagoux Q, Richard I. Deciphering the Molecular Mechanism of Incurable Muscle Disease by a Novel Method for the Interpretation of miRNA Dysregulation. Non-Coding RNA. 2022; 8(4):48. https://doi.org/10.3390/ncrna8040048
Chicago/Turabian StyleIsraeli, David, Ai Vu Hong, Guillaume Corre, Quentin Miagoux, and Isabelle Richard. 2022. "Deciphering the Molecular Mechanism of Incurable Muscle Disease by a Novel Method for the Interpretation of miRNA Dysregulation" Non-Coding RNA 8, no. 4: 48. https://doi.org/10.3390/ncrna8040048