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Article

Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films

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Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, India
2
Institute of Pharmacy and Technology, Salipur 754202, India
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SABIC Polymer Research Center, Department of Chemical Engineering, King Saud University, Riyadh 11451, Saudi Arabia
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The Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, 220141 Minsk, Belarus
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Department of Food Process Engineering, National Institute of Technology, Rourkela 769008, India
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Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur, Chennai 603203, India
*
Authors to whom correspondence should be addressed.
These authors contributed equally.
Academic Editors: Mazeyar Parvinzadeh Gashti and Filippo Rossi
Received: 23 December 2020 / Revised: 13 March 2021 / Accepted: 21 April 2021 / Published: 6 May 2021
In the present study, we report the development of poly (vinyl alcohol) (PVA) and chitosan oligosaccharide (COS)-based novel blend films. The concentration of COS was varied between 2.5–10.0 wt% within the films. The inclusion of COS added a brown hue to the films. FTIR spectroscopy revealed that the extent of intermolecular hydrogen bonding was most prominent in the film that contained 5.0 wt% of COS. The diffractograms showed that COS altered the degree of crystallinity of the films in a composition-dependent manner. As evident from the thermal analysis, COS content profoundly impacted the evaporation of water molecules from the composite films. Stress relaxation studies demonstrated that the blend films exhibited more mechanical stability as compared to the control film. The impedance profiles indicated the capacitive-dominant behavior of the prepared films. Ciprofloxacin HCl-loaded films showed excellent antimicrobial activity against Escherichia coli and Bacillus cereus. The prepared films were observed to be biocompatible. Hence, the prepared PVA/COS-based blend films may be explored for drug delivery applications. View Full-Text
Keywords: poly (vinyl alcohol); chitosan oligosaccharide; blends; films; semicrystalline; drug delivery poly (vinyl alcohol); chitosan oligosaccharide; blends; films; semicrystalline; drug delivery
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MDPI and ACS Style

Qureshi, D.; Sahoo, A.; Mohanty, B.; Anis, A.; Kulikouskaya, V.; Hileuskaya, K.; Agabekov, V.; Sarkar, P.; Ray, S.S.; Maji, S.; Pal, K. Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films. Gels 2021, 7, 55. https://doi.org/10.3390/gels7020055

AMA Style

Qureshi D, Sahoo A, Mohanty B, Anis A, Kulikouskaya V, Hileuskaya K, Agabekov V, Sarkar P, Ray SS, Maji S, Pal K. Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films. Gels. 2021; 7(2):55. https://doi.org/10.3390/gels7020055

Chicago/Turabian Style

Qureshi, Dilshad, Ayasharani Sahoo, Biswaranjan Mohanty, Arfat Anis, Viktoryia Kulikouskaya, Kseniya Hileuskaya, Vladimir Agabekov, Preetam Sarkar, Sirsendu S. Ray, Samarendra Maji, and Kunal Pal. 2021. "Fabrication and Characterization of Poly (vinyl alcohol) and Chitosan Oligosaccharide-Based Blend Films" Gels 7, no. 2: 55. https://doi.org/10.3390/gels7020055

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