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Supermacroporous Composite Cryogels in Biomedical Applications

Department of Chemistry, Hacettepe University, 06800 Ankara, Turkey
Author to whom correspondence should be addressed.
Received: 19 March 2019 / Revised: 10 April 2019 / Accepted: 11 April 2019 / Published: 17 April 2019
(This article belongs to the Special Issue Cryogelation and Cryogels)
PDF [7399 KB, uploaded 29 April 2019]


Supermacroporous gels, called cryogels, are unique scaffolds that can be prepared by polymerization of monomer solution under sub-zero temperatures. They are widely used in many applications and have significant potential biomaterials, especially for biomedical applications due to their inherent interconnected supermacroporous structures and easy formation of composite polymers in comparison to other porous polymer synthesis techniques. This review highlights the fundamentals of supermacroporous cryogels and composite cryogels, and then comprehensively summarizes recent studies in preparation, functionalization, and utilization with mechanical, biological and physicochemical features, according to the biomedical applications. Furthermore, conclusions and outlooks are discussed for the use of these promising and durable supermacroporous composite cryogels. View Full-Text
Keywords: biomedical application; composite; cryogel; polymer; supermacroporous biomedical application; composite; cryogel; polymer; supermacroporous

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Saylan, Y.; Denizli, A. Supermacroporous Composite Cryogels in Biomedical Applications. Gels 2019, 5, 20.

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