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Case Report

Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases

by
Alessandra Mularoni
1,
Elena Graziano
1,2,*,
Alice Annalisa Medaglia
3,
Barbara Buscemi
4,
Taylor Eddens
5,
Lavinia Martino
6,
Daniele Di Carlo
7,
Antonio Cascio
8,
Pier Giulio Conaldi
7,
Alessandro Bertani
9 and
Paolo Antonio Grossi
10
1
Department of Infectious Diseases, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), 90127 Palermo, Italy
2
Division of Infectious Diseases, Department of Medicine, University of Udine, Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), 33100 Udine, Italy
3
Infectious and Tropical Disease Unit, AOU Policlinico “P. Giaccone”, 90127 Palermo, Italy
4
Department of Nephrology, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), 90127 Palermo, Italy
5
Division of Allergy/Immunology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA 15224, USA
6
Department of Pulmonology, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), 90127 Palermo, Italy
7
Department of Laboratory Medicine and Advanced Biotechnologies, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), 90127 Palermo, Italy
8
Infectious Diseases Unit, Internal Medicine and Medical Specialties, Department of Health Promotion, Mother and Child Care, University of Palermo, 90127 Palermo, Italy
9
Department of Thoracic Surgery, IRCCS-ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), 90127 Palermo, Italy
10
Infectious and Tropical Diseases Unit, Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy
*
Author to whom correspondence should be addressed.
J. Fungi 2021, 7(12), 1057; https://doi.org/10.3390/jof7121057
Submission received: 23 November 2021 / Revised: 8 December 2021 / Accepted: 8 December 2021 / Published: 10 December 2021
(This article belongs to the Topic Fungal Infections in Immunocompromised Hosts)
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Abstract

Emerging fungal infections are a major challenge in solid organ transplantation (SOT) and are associated with high morbidity and mortality. We report two cases of Malassezia restricta pneumonia in SOT recipients. Infections were diagnosed with molecular analysis and histology. Patients were treated with antifungal therapy and have fully recovered.
Keywords: lung transplant; kidney transplant; emerging fungal infections; Malassezia restricta lung transplant; kidney transplant; emerging fungal infections; Malassezia restricta

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MDPI and ACS Style

Mularoni, A.; Graziano, E.; Medaglia, A.A.; Buscemi, B.; Eddens, T.; Martino, L.; Di Carlo, D.; Cascio, A.; Conaldi, P.G.; Bertani, A.; et al. Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases. J. Fungi 2021, 7, 1057. https://doi.org/10.3390/jof7121057

AMA Style

Mularoni A, Graziano E, Medaglia AA, Buscemi B, Eddens T, Martino L, Di Carlo D, Cascio A, Conaldi PG, Bertani A, et al. Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases. Journal of Fungi. 2021; 7(12):1057. https://doi.org/10.3390/jof7121057

Chicago/Turabian Style

Mularoni, Alessandra, Elena Graziano, Alice Annalisa Medaglia, Barbara Buscemi, Taylor Eddens, Lavinia Martino, Daniele Di Carlo, Antonio Cascio, Pier Giulio Conaldi, Alessandro Bertani, and et al. 2021. "Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases" Journal of Fungi 7, no. 12: 1057. https://doi.org/10.3390/jof7121057

APA Style

Mularoni, A., Graziano, E., Medaglia, A. A., Buscemi, B., Eddens, T., Martino, L., Di Carlo, D., Cascio, A., Conaldi, P. G., Bertani, A., & Grossi, P. A. (2021). Malassezia restricta Pneumonia in Solid Organ Transplant Recipients: First Report of Two Cases. Journal of Fungi, 7(12), 1057. https://doi.org/10.3390/jof7121057

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