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Metabolites from Clonostachys Fungi and Their Biological Activities

Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China
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J. Fungi 2020, 6(4), 229; https://doi.org/10.3390/jof6040229
Received: 9 September 2020 / Revised: 7 October 2020 / Accepted: 12 October 2020 / Published: 16 October 2020
Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in Clonostachys fungi and biological activities.
Keywords: secondary metabolites; Clonostachys fungi; Bionectria; Gliocladium; Nectria; structural diversity; biological activities secondary metabolites; Clonostachys fungi; Bionectria; Gliocladium; Nectria; structural diversity; biological activities
MDPI and ACS Style

Han, P.; Zhang, X.; Xu, D.; Zhang, B.; Lai, D.; Zhou, L. Metabolites from Clonostachys Fungi and Their Biological Activities. J. Fungi 2020, 6, 229.

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