Next Article in Journal
Effectiveness of the Entomopathogenic Fungal Species Metarhizium anisopliae Strain NCAIM 362 Treatments against Soil Inhabiting Melolontha melolontha Larvae in Sweet Potato (Ipomoea batatas L.)
Next Article in Special Issue
Pan-Echinocandin-Resistant Candida glabrata Bloodstream Infection Complicating COVID-19: A Fatal Case Report
Previous Article in Journal
Alternatives in Molecular Diagnostics of Encephalitozoon and Enterocytozoon Infections
Previous Article in Special Issue
Is the COVID-19 Pandemic a Good Time to Include Aspergillus Molecular Detection to Categorize Aspergillosis in ICU Patients? A Monocentric Experience
Review

COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges

1
Department of Microbiology, Our Lady of Lourdes Hospital Drogheda, A92 VW28 Co. Louth, Ireland
2
Department of Clinical Microbiology, Trinity College Dublin, St. James’s Hospital Campus, D08 NHY1 Dublin, Ireland
3
Department of Microbiology, Royal College of Surgeons, Ireland, D02 YN77 Dublin, Ireland
*
Author to whom correspondence should be addressed.
J. Fungi 2020, 6(3), 115; https://doi.org/10.3390/jof6030115
Received: 3 July 2020 / Revised: 18 July 2020 / Accepted: 20 July 2020 / Published: 22 July 2020
(This article belongs to the Special Issue Fungal Infections Complicating COVID-19)
Aspergillus co-infection in patients with severe coronavirus disease 2019 (COVID-19) pneumonia, leading to acute respiratory distress syndrome, has recently been reported. To date, 38 cases have been reported, with other cases most likely undiagnosed mainly due to a lack of clinical awareness and diagnostic screening. Importantly, there is currently no agreed case definition of COVID-19 associated invasive pulmonary aspergillosis (CAPA) that could aid in the early detection of this co-infection. Additionally, with the global emergence of triazole resistance, we emphasize the importance of antifungal susceptibility testing in order to ensure appropriate antifungal therapy. Herein is a review of 38 published CAPA cases, which highlights the diagnostic and therapeutic challenges posed by this novel fungal co-infection. View Full-Text
Keywords: COVID-19 pneumonia; invasive pulmonary aspergillosis; diagnosis; multi-triazole resistance; COVID-19 associated invasive pulmonary aspergillosis COVID-19 pneumonia; invasive pulmonary aspergillosis; diagnosis; multi-triazole resistance; COVID-19 associated invasive pulmonary aspergillosis
MDPI and ACS Style

Mohamed, A.; Rogers, T.R.; Talento, A.F. COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges. J. Fungi 2020, 6, 115. https://doi.org/10.3390/jof6030115

AMA Style

Mohamed A, Rogers TR, Talento AF. COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges. Journal of Fungi. 2020; 6(3):115. https://doi.org/10.3390/jof6030115

Chicago/Turabian Style

Mohamed, Aia, Thomas R. Rogers, and Alida F. Talento. 2020. "COVID-19 Associated Invasive Pulmonary Aspergillosis: Diagnostic and Therapeutic Challenges" Journal of Fungi 6, no. 3: 115. https://doi.org/10.3390/jof6030115

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop