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J. Fungi 2018, 4(3), 87; https://doi.org/10.3390/jof4030087

Challenges and Opportunities in the Management of Onychomycosis

1
Faculty of Health, University of Canberra, Bruce, Canberra, ACT 2601, Australia
2
Faculty of Health, University of Tasmania, Hobart, TAS 7005, Australia
3
The Canberra Hospital, Yamba Drive, Garran, ACT 2605, Australia
*
Author to whom correspondence should be addressed.
Received: 5 July 2018 / Revised: 19 July 2018 / Accepted: 23 July 2018 / Published: 24 July 2018
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Abstract

Onychomycosis is an increasingly common fungal nail infection, chiefly caused by dermatophyte fungi. The disease is notoriously difficult to treat due to the deep-seated nature of fungi within the nail plate, prolonged treatment requirements, poor patient adherence and frequent recurrences. Given the poor efficacy of currently available topical and systemic therapies, there is a renewed interest in exploring alternative treatment modalities for onychomycosis. Natural therapies, physical treatments and various combination therapies have all shown potential for the management of onychomycosis, though research on many of these methods is still in preliminary stages. Further large, well-designed, randomised controlled trials are necessary to confirm the efficacy of these novel treatments in order to make formal recommendations regarding their use in the management of onychomycosis. View Full-Text
Keywords: onychomycosis; nail; fungi; infection; treatment; alternative treatment; combination therapy onychomycosis; nail; fungi; infection; treatment; alternative treatment; combination therapy
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Christenson, J.K.; Peterson, G.M.; Naunton, M.; Bushell, M.; Kosari, S.; Baby, K.E.; Thomas, J. Challenges and Opportunities in the Management of Onychomycosis. J. Fungi 2018, 4, 87.

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