Estimation of the Burden of Serious Human Fungal Infections in Malaysia
Abstract
:1. Introduction
2. Material and Methods
3. Results
3.1. HIV/AIDS and AIDS-Defining Fungal Infections
3.2. Pulmonary Mycoses
3.3. Invasive Fungal Infections
3.4. Fungal Keratitis
3.5. Recurrent Vaginal Candidiasis
4. Discussion
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Fungal Infection | Number of Infections per Underlying Disorder per Year | Total Burden | Rate/100,000 | ||||
---|---|---|---|---|---|---|---|
None | HIV/AIDS | Respiratory | Cancer/Tx | ICU | |||
Oesophageal candidiasis | - | 5850 | - | - | - | 5850 | 19 |
Candidaemia | - | - | - | 1073 | 460 | 1533 | 5 |
Candida peritonitis | 230 | 230 | 0.8 | ||||
Recurrent vaginal candidiasis (>4×/year) | 501,138 | - | - | - | - | 501,138 | 4800 * |
ABPA | - | - | 30,062 | - | - | 30,062 | 98 |
SAFS | - | - | 39,682 | 39,682 | 130 | ||
Chronic pulmonary aspergillosis | - | - | 7635 | - | - | 7635 | 24.9 |
Invasive aspergillosis | - | - | 184 | 834 | 1018 | 3.3 | |
Cryptococcal meningitis | 47 | 700 | - | 108 | - | 855 | 2.8 |
Pneumocystis pneumonia | - | 1286 | - | - | - | 1286 | 4.2 |
Histoplasmosis | 175 | 175 | 0.6 | ||||
T. marneffei infection | 350 | 350 | 1.1 | ||||
Fungal keratitis | 400 | 400 | 1.3 | ||||
Total burden estimated | 501,585 | 8361 | 77,379 | 1365 | 1524 | 590,214 |
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Velayuthan, R.D.; Samudi, C.; Lakhbeer Singh, H.K.; Ng, K.P.; Shankar, E.M.; Denning, D.W. Estimation of the Burden of Serious Human Fungal Infections in Malaysia. J. Fungi 2018, 4, 38. https://doi.org/10.3390/jof4010038
Velayuthan RD, Samudi C, Lakhbeer Singh HK, Ng KP, Shankar EM, Denning DW. Estimation of the Burden of Serious Human Fungal Infections in Malaysia. Journal of Fungi. 2018; 4(1):38. https://doi.org/10.3390/jof4010038
Chicago/Turabian StyleVelayuthan, Rukumani Devi, Chandramathi Samudi, Harvinder Kaur Lakhbeer Singh, Kee Peng Ng, Esaki M. Shankar, and David W. Denning. 2018. "Estimation of the Burden of Serious Human Fungal Infections in Malaysia" Journal of Fungi 4, no. 1: 38. https://doi.org/10.3390/jof4010038