Next Article in Journal
Eosinophilia and Quality of Life in Patients Receiving a Bioabsorbable Steroid-Eluting Implant during Endoscopic Sinus Surgery
Previous Article in Journal
A Systematic Review of the Treatment of Chronic Rhinosinusitis in Adults with Primary Ciliary Dyskinesia
Article Menu

Export Article

From the third issue of 2018, Sinusitis has changed its name to Sinusitis and Asthma.

Open AccessCase Report
Sinusitis 2017, 2(1), 2;

Rhabdomyosarcoma of the Paranasal Sinuses Initially Diagnosed as Acute Sinusitis

Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Author to whom correspondence should be addressed.
Academic Editor: César Picado
Received: 14 November 2016 / Revised: 15 January 2017 / Accepted: 16 January 2017 / Published: 4 February 2017
Full-Text   |   PDF [2479 KB, uploaded 4 February 2017]   |  


Rhabdomyosarcoma (RMS) is an uncommon soft tissue malignancy that is typically found in the pediatric population. Here we describe a rare case of widely metastatic alveolar RMS of the right paranasal sinuses in an adult woman who presented with several months of unilateral sinus symptoms that was initially misdiagnosed as acute sinusitis. A middle-aged female presented with two months of right sinus pressure and unilateral epistaxis. She had previously been diagnosed with acute sinusitis and was treated with antibiotics without improvement. Nasal endoscopy demonstrated a fungating right nasal cavity mass. On computed tomography scan (CT), she was found to have metastatic disease in the mediastinum, lungs, bones, pancreas, and right ovary. Pathology of the nasal cavity mass was consistent with alveolar RMS. The patient initially responded well to chemotherapy, but subsequently developed brain and leptomeningeal metastases. This case of sinonasal rhabdomyosarcoma is unique in the extent of metastatic disease at the time of diagnosis and the initial misdiagnosis despite concerning unilateral symptoms and imaging. This thus highlights the importance of maintaining a high index of suspicion for malignancy in patients with unilateral sinus symptoms. View Full-Text
Keywords: unilateral; sinusitis; rhabdomyosarcoma unilateral; sinusitis; rhabdomyosarcoma

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Dilger, A.E.; Schneider, A.L.; Cramer, J.; Shintani Smith, S. Rhabdomyosarcoma of the Paranasal Sinuses Initially Diagnosed as Acute Sinusitis. Sinusitis 2017, 2, 2.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics



[Return to top]
Sinusitis EISSN 2309-107X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top