Rapid Resolution of Large Bowel Diarrhea after the Administration of a Combination of a High-Fiber Diet and a Probiotic Mixture in 30 Dogs
by
Giacomo Rossi 1, Matteo Cerquetella 1, Alessandra Gavazza 1,*, Livio Galosi 1, Sara Berardi 1, Sara Mangiaterra 1, Subeide Mari 1, Jan S. Suchodolski 2, Jonathan A. Lidbury 2, Joerg M. Steiner 2 and Graziano Pengo 3
Giacomo Rossi 1, Matteo Cerquetella 1, Alessandra Gavazza 1,*, Livio Galosi 1, Sara Berardi 1, Sara Mangiaterra 1, Subeide Mari 1, Jan S. Suchodolski 2, Jonathan A. Lidbury 2, Joerg M. Steiner 2 and Graziano Pengo 3
1
School of Biosciences and Veterinary Medicine, University of Camerino, Via Circonvallazione 93/95, 62024 Matelica (MC), Italy
2
Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX 77843, USA
3
St. Antonio Veterinary Clinic, S.S. 415 Paullese 6, 26020 Madignano (CR), Italy
*
Author to whom correspondence should be addressed.
Vet. Sci. 2020, 7(1), 21; https://doi.org/10.3390/vetsci7010021
Received: 9 January 2020 / Revised: 6 February 2020 / Accepted: 7 February 2020 / Published: 10 February 2020
(This article belongs to the Section Clinical Veterinary Medicine)
Canine fiber responsive diarrhea is a form of chronic colitis that improves clinically after adding fiber to the diet. In the present study, we investigated the effect of a combination of a high-fiber, highly digestible, hypoallergenic diet with a probiotic mixture in 30 dogs with chronic colitis that were unresponsive to various dietary and/or pharmacological interventions. Fecal scores, canine chronic enteropathy clinical activity index (CCECAI) scores, the dysbiosis index (DI), and histologic images of colonic biopsies were evaluated. At baseline (day 0; T0) and after 30 days of treatment (T1), all variables evaluated in our patients (i.e., fecal and CCECAI scores and histopathology) improved significantly at T1, with the exception of DI. However, there was a numerical shift from a state of dysbiosis to one of normobiosis. The combination of the diet and the probiotic used in the present study induced the resolution of clinical signs in a mean of 8.5 days (maximum 15 days) and did not necessitate any other treatments or the further addition of alimentary fiber.
Keywords:
colitis; food responsive diarrhea; gut homeostasis; high fiber; therapy
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Rossi, G.; Cerquetella, M.; Gavazza, A.; Galosi, L.; Berardi, S.; Mangiaterra, S.; Mari, S.; Suchodolski, J.S.; Lidbury, J.A.; Steiner, J.M.; Pengo, G. Rapid Resolution of Large Bowel Diarrhea after the Administration of a Combination of a High-Fiber Diet and a Probiotic Mixture in 30 Dogs. Vet. Sci. 2020, 7, 21.
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