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Open AccessCase Report

Sertoli Cell Tumor (SCT) in a Captive Black Bear (Ursus americanus)

1
Department of Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea
2
Stem Cell Therapeutic Research Institute, Kyungpook National University, Daegu 41566, Korea
3
Samsung Everland Zoological Garden, Yongin-si, Gyeonggido 17203, Korea
4
Department of Veterinary Pathology, College of Veterinary Medicine, Gyeongsang National University, Jinju 52828, Korea
*
Authors to whom correspondence should be addressed.
Vet. Sci. 2019, 6(4), 77; https://doi.org/10.3390/vetsci6040077
Received: 6 August 2019 / Revised: 23 September 2019 / Accepted: 25 September 2019 / Published: 26 September 2019
A black bear of 29-year-old (Ursus americanus) died unexpectedly in captivity without any gross lesions or clinical signs. We identified a firm, lobulated, yellowish tan, and well-circumscribed mass embedded inside the testicular tissue at the time of necropsy. The tumor sections exhibited soft necrotic and hemorrhagic areas beneath its capsule. Histologically, the tumor comprised Sertoli cells arranged in tubules and solid sheets supported by prominent fibrous connective tissues. The Sertoli cells were positive for vimentin and ER-β expression, whereas it showed negative staining for inhibin-α, cytokeratin 19, and S-100. To the best of our knowledge, this is the rare case report of testicular Sertoli cell tumor in black bear. View Full-Text
Keywords: Sertoli cells; testes; Ursidae; neoplasm; vimentin Sertoli cells; testes; Ursidae; neoplasm; vimentin
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Elfadl, A.K.; Park, S.; Ullah, H.M.A.; Youn, S.-H.; Chung, M.-J.; Son, J.-Y.; Lee, J.-Y.; Lee, S.-W.; Lee, A.-R.; Baek, S.-M.; Jeon, S.-G.; Lee, E.-J.; Hong, I.-H.; Park, J.-K.; Jeong, K.-S. Sertoli Cell Tumor (SCT) in a Captive Black Bear (Ursus americanus). Vet. Sci. 2019, 6, 77.

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