Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication
Abstract
:Simple Summary
Abstract
1. Introduction
2. Case Presentation
3. Discussion
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Reference Interval | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | |
---|---|---|---|---|---|---|---|---|---|
Hematocrit (%) | 50–55 | 62.3 | 60.6 | 55.3 | |||||
Neutrophils (cells/μL) | 3000–10,500 | 8847 | 8204 | ||||||
Lymphocytes (cells/μL) | 1200–4000 | 2181 | 1875 | ||||||
Eosinophils (cells/μL) | 0–1500 | 485 | 527 | ||||||
Platelets (cells/μL) | 150,000–400,000 | 70,000 (clumps seen) | 126,000 (clumps seen) | ||||||
Sodium (mmol/L) | 143–151 | 148 | 145 | 151 | |||||
Potassium (mmol/L) | 3.6–4.8 | 4.4 | 4.5 | 4.7 | |||||
ALT (IU/L) | 21–72 | 13,288 | 10,343 | 6007 | 4103 | 3270 | 2555 | 1993 | 1674 |
AST (IU/L) | 20–49 | 1830 | 467 | 167 | 135 | 110 | 73 | 69 | 73 |
ALP (IU/L) | 14–91 | 1508 | 1783 | 1567 | 1387 | 1502 | 1509 | 1465 | 1550 |
GGT (IU/L) | 0–5 | 17 | 18 | 13 | 8 | 11 | 20 | 5 | 7 |
Albumin (g/dL) | 3.4–4.3 | 3.3 | 3.3 | 3 | 2.6 | 2.8 | 2.9 | 3.1 | 3.3 |
Globulin (g/dL) | 1.7–3.1 | 1.6 | 2.1 | 1.9 | 1.9 | 2.2 | 2.4 | 2.5 | 2.9 |
Cholesterol (mg/dL) | 139–353 | 188 | 193 | 137 | 105 | 101 | 99 | 99 | 104 |
Total Bilirubin (mg/dL) | 0.0–0.2 | 1.4 | 2.1 | 1.4 | 0.9 | 0.6 | 0.5 | 0.5 | 0.5 |
Glucose (mg/dL) | 86–118 | 73 | 87 | 74 | 149 | 82 | 90 | 63 | 51 |
Creatinine (mg/dL) | 0.8–1.5 | 0.8 | 0.7 | 0.9 | |||||
Blood Urea Nitrogen (mg/dL) | 11–33 | 17 | 9 | 5 | 4 | 8 | 10 | 10 | 15 |
PT (s) | 7.0–9.3 | 21.4 | 9.9 | 8.2 | |||||
aPTT (s) | 10.4–12.9 | 21 | 15.7 | 13.9 | |||||
Fibrinogen (mg/dL) | 109–311 | <50 | 119 | 210 | |||||
D-dimers (ng/dL) | 0–186 | 904 | 58 | 181 |
Reference Interval | Day 15 | |
---|---|---|
ALT (IU/L) | 21–72 | 214 |
AST (IU/L) | 20–49 | 33 |
ALP (IU/L) | 14–91 | 893 |
GGT (IU/L) | 0–5 | <3 |
Albumin (g/dL) | 3.4–4.3 | 3.7 |
Globulin (g/dL) | 1.7–3.1 | 2.5 |
Cholesterol (mg/dL) | 139–353 | 100 |
Total Bilirubin (mg/dL) | 0.0–0.2 | 0.2 |
Glucose (mg/dL) | 86–118 | 91 |
Creatinine (mg/dL) | 0.8–1.5 | |
Blood Urea Nitrogen (mg/dL) | 11–33 | 39 |
PT (s) | 7.0–9.3 | 8.3 |
aPTT (s) | 10.4–12.9 | 15.2 |
Fibrinogen (mg/dL) | 109–311 | 160 |
D-dimers (ng/dL) | 0–186 | 72 |
Reference Interval | Day 24 | Day 26 | Day 34 | Day 50 | |
---|---|---|---|---|---|
Hematocrit (%) | 50–55 | 56.9 | |||
Neutrophils (cells/μL) | 3000–10,500 | 6261 | |||
Lymphocytes (cells/μL) | 1200–4000 | 3010 | |||
Eosinophils (cells/μL) | 0–1500 | 1806 | |||
Platelets (cells/μL) | 150,000–400,000 | 34,000 (clumps seen) | |||
Sodium (mmol/L) | 143–151 | 131 | 134 | 154 | 152 |
Potassium (mmol/L) | 3.6–4.8 | 5.6 | 5.5 | 4.0 | 3.9 |
ALT (IU/L) | 21–72 | 85 | 69 | 174 | 108 |
AST (IU/L) | 20–49 | 84 | 50 | 40 | 26 |
ALP (IU/L) | 14–91 | 447 | 356 | 968 | 353 |
GGT (IU/L) | 0–5 | <3 | <3 | <3 | <3 |
Albumin (g/dL) | 3.4–4.3 | 3.3 | 3.1 | 3.3 | 3.7 |
Globulin (g/dL) | 1.7–3.1 | 2.6 | 2.1 | 2.0 | 2.3 |
Cholesterol (mg/dL) | 139–353 | 78 | 68 | 106 | 164 |
Total Bilirubin (mg/dL) | 0.0–0.2 | 0.3 | 0.2 | <0.2 | <0.2 |
Glucose (mg/dL) | 86–118 | 43 | 120 | 117 | 114 |
Creatinine (mg/dL) | 0.8–1.5 | 0.8 | 0.6 | 0.6 | |
Blood Urea Nitrogen (mg/dL) | 11–33 | 28 | 19 | 7 | 8 |
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Cohen, E.A.; Moeller, C.M.; Dear, J.D. Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication. Vet. Sci. 2023, 10, 500. https://doi.org/10.3390/vetsci10080500
Cohen EA, Moeller CM, Dear JD. Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication. Veterinary Sciences. 2023; 10(8):500. https://doi.org/10.3390/vetsci10080500
Chicago/Turabian StyleCohen, Emily A., Courtney M. Moeller, and Jonathan D. Dear. 2023. "Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication" Veterinary Sciences 10, no. 8: 500. https://doi.org/10.3390/vetsci10080500