Next Article in Journal
Cardiac Arrhythmia Classification by Multi-Layer Perceptron and Convolution Neural Networks
Previous Article in Journal
Efficient Computational Design of a Scaffold for Cartilage Cell Regeneration
Article Menu
Issue 2 (June) cover image

Export Article

Open AccessArticle

Kinetic Modeling of Corn Fermentation with S. cerevisiae Using a Variable Temperature Strategy

Agricultural and Biosystems Engineering Department, Iowa State University, Elings Hall, 605 Bissell Road, Ames, IA 50011, USA
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Bioengineering 2018, 5(2), 34;
Received: 30 March 2018 / Revised: 21 April 2018 / Accepted: 21 April 2018 / Published: 24 April 2018
PDF [1064 KB, uploaded 24 April 2018]


While fermentation is usually done at a fixed temperature, in this study, the effect of having a controlled variable temperature was analyzed. A nonlinear system was used to model batch ethanol fermentation, using corn as substrate and the yeast Saccharomyces cerevisiae, at five different fixed and controlled variable temperatures. The lower temperatures presented higher ethanol yields but took a longer time to reach equilibrium. Higher temperatures had higher initial growth rates, but the decay of yeast cells was faster compared to the lower temperatures. However, in a controlled variable temperature model, the temperature decreased with time with the initial value of 40 C. When analyzing a time window of 60 h, the ethanol production increased 20% compared to the batch with the highest temperature; however, the yield was still 12% lower compared to the 20 C batch. When the 24 h’ simulation was analyzed, the controlled model had a higher ethanol concentration compared to both fixed temperature batches. View Full-Text
Keywords: fermentation; Saccharomyces cerevisiae; kinetic modeling fermentation; Saccharomyces cerevisiae; kinetic modeling

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Souza, A.C.M.; Mousaviraad, M.; Mapoka, K.O.M.; Rosentrater, K.A. Kinetic Modeling of Corn Fermentation with S. cerevisiae Using a Variable Temperature Strategy. Bioengineering 2018, 5, 34.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Bioengineering EISSN 2306-5354 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top