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Bioengineering
Volume 12
Issue 9
10.3390/bioengineering12090931
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Review

Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life

by
Alessia Bramanti
1,
Colomba Pessolano
1,*,
Marina Garofano
1,*,
Angelo Antonio Maglio
1,
Michele Ciccarelli
1,
Luana Budaci
2,
Mariaconsiglia Calabrese
1,
Andrea Marino
1,
Francesco Loria
2,
Francesco Corallo
3,
Placido Bramanti
4,
Carmine Vecchione
1 and
Alessandro Vatrella
1
1
Department of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, 84081 Baronissi, Italy
2
Azienda Ospedaliero-Universitaria “San Giovanni di Dio e Ruggi d’Aragona”, Via San Leonardo, 84125 Salerno, Italy
3
IRCCS Centro Neurolesi Bonino-Pulejo, Via Palermo, S.S. 113, C.da Casazza, 98124 Messina, Italy
4
Faculty of Psychology, Università degli Studi eCampus, Via Isimbardi 10, 22060 Novedrate, Italy
*
Authors to whom correspondence should be addressed.
Bioengineering 2025, 12(9), 931; https://doi.org/10.3390/bioengineering12090931 (registering DOI)
Submission received: 29 July 2025 / Revised: 27 August 2025 / Accepted: 27 August 2025 / Published: 29 August 2025
(This article belongs to the Special Issue Physical Therapy and Rehabilitation)
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Abstract

(1) Background: Chronic pulmonary diseases (CPDs), such as COPD, asthma, and interstitial lung disease, are often accompanied by psychological distress and reduced quality of life. Mindfulness-Based Interventions (MBIs), including digital and virtual reality (VR) formats, have emerged as promising non-pharmacological approaches to improve symptom management and well-being. This systematic review aimed to evaluate the effectiveness of MBIs—delivered in-person or digitally—on anxiety, depression, disease-related stress, dyspnea, and health-related quality of life in individuals with CPDs. (2) Methods: A systematic review was conducted following PRISMA guidelines across PubMed, Scopus, and Web of Science (2005–2025). Thirteen studies (8 randomized controlled trials, 5 non-randomized) met inclusion criteria. Outcomes assessed included psychological distress, physical symptoms, and health-related quality of life (HRQoL). Risk of bias was evaluated using RoB 2 and ROBINS-I tools. (3) Results: MBIs were associated with improvements in anxiety, depression, stress, and HRQoL in several studies. Interventions were generally well-tolerated and effective across various delivery methods, including digital and VR-based formats. Improvements were especially notable when interventions were tailored and sustained. (4) Conclusions: MBIs, including digital and VR-delivered formats, show promise in supporting psychological and physical outcomes in CPD populations. They represent a feasible and complementary tool in modern respiratory care.
Keywords: mindfulness-based interventions; chronic pulmonary disease; virtual reality; psychological distress; quality of life mindfulness-based interventions; chronic pulmonary disease; virtual reality; psychological distress; quality of life
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MDPI and ACS Style

Bramanti, A.; Pessolano, C.; Garofano, M.; Maglio, A.A.; Ciccarelli, M.; Budaci, L.; Calabrese, M.; Marino, A.; Loria, F.; Corallo, F.; et al. Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life. Bioengineering 2025, 12, 931. https://doi.org/10.3390/bioengineering12090931

AMA Style

Bramanti A, Pessolano C, Garofano M, Maglio AA, Ciccarelli M, Budaci L, Calabrese M, Marino A, Loria F, Corallo F, et al. Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life. Bioengineering. 2025; 12(9):931. https://doi.org/10.3390/bioengineering12090931

Chicago/Turabian Style

Bramanti, Alessia, Colomba Pessolano, Marina Garofano, Angelo Antonio Maglio, Michele Ciccarelli, Luana Budaci, Mariaconsiglia Calabrese, Andrea Marino, Francesco Loria, Francesco Corallo, and et al. 2025. "Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life" Bioengineering 12, no. 9: 931. https://doi.org/10.3390/bioengineering12090931

APA Style

Bramanti, A., Pessolano, C., Garofano, M., Maglio, A. A., Ciccarelli, M., Budaci, L., Calabrese, M., Marino, A., Loria, F., Corallo, F., Bramanti, P., Vecchione, C., & Vatrella, A. (2025). Mindfulness-Based Interventions for Chronic Pulmonary Diseases: A Systematic Review of Effects on Anxiety, Depression, Stress, Dyspnea, and Quality of Life. Bioengineering, 12(9), 931. https://doi.org/10.3390/bioengineering12090931

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