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Use of Herbal Medications for Treatment of Osteoarthritis and Rheumatoid Arthritis

Department of Pharmaceutical and Administrative Sciences, Presbyterian College School of Pharmacy, 307 North Broad Street, Clinton, SC 29325, USA
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Medicines 2020, 7(11), 67; https://doi.org/10.3390/medicines7110067
Received: 6 August 2020 / Revised: 21 October 2020 / Accepted: 23 October 2020 / Published: 28 October 2020
Arthritis is a chronic condition that affects nearly a quarter of the United States population. Osteoarthritis (OA) and rheumatoid arthritis (RA) are two major forms of arthritis associated with severe joint pain and reduced quality of life. Various pharmacological interventions may be utilized for arthritis treatment when non-pharmacological therapy is insufficient. However, pharmacological therapy can be associated with serious side effects and high costs. Therefore, alternative therapies have been under investigation. Herbal medications have shown the potential for safe and effective management of arthritis. For this review, we attempt to summarize the mechanisms, safety, and efficacy of herbal treatments for OA and RA. After searching electronic databases, we identified nine herbs among 23 clinical trials used for the treatment of OA or RA patients. Improvement of OA and RA symptoms, pain, and inflammation was demonstrated. The herbs exhibited strong anti-inflammatory and anti-oxidant activities, contributing to a reduction in inflammation and tissue damage. Several herbs elucidated new mechanisms for OA and RA treatment as well. Though these herbs have shown promise for OA and RA treatment, more studies and clinical trials are required for determining safety and efficacy, bioactivity, and optimal bioavailability. View Full-Text
Keywords: herb; osteoarthritis; rheumatoid arthritis; pain; inflammation herb; osteoarthritis; rheumatoid arthritis; pain; inflammation
MDPI and ACS Style

Lindler, B.N.; Long, K.E.; Taylor, N.A.; Lei, W. Use of Herbal Medications for Treatment of Osteoarthritis and Rheumatoid Arthritis. Medicines 2020, 7, 67. https://doi.org/10.3390/medicines7110067

AMA Style

Lindler BN, Long KE, Taylor NA, Lei W. Use of Herbal Medications for Treatment of Osteoarthritis and Rheumatoid Arthritis. Medicines. 2020; 7(11):67. https://doi.org/10.3390/medicines7110067

Chicago/Turabian Style

Lindler, Breanna N.; Long, Katelyn E.; Taylor, Nancy A.; Lei, Wei. 2020. "Use of Herbal Medications for Treatment of Osteoarthritis and Rheumatoid Arthritis" Medicines 7, no. 11: 67. https://doi.org/10.3390/medicines7110067

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