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Open AccessArticle

Intra-Articular Laser Treatment Plus Platelet Rich Plasma (PRP) Significantly Reduces Pain in Many Patients Who Had Failed Prior PRP Treatment

1
Illinois Sportsmedicine & Orthopaedic Centers, 1714 Milwaukee Ave, Glenview, IL 60025, USA
2
Advanced Physical Therapy Institute, 1714 Milwaukee Ave, Glenview, IL 6002, USA
*
Author to whom correspondence should be addressed.
Medicines 2019, 6(3), 75; https://doi.org/10.3390/medicines6030075
Received: 28 May 2019 / Revised: 3 July 2019 / Accepted: 10 July 2019 / Published: 16 July 2019
(This article belongs to the Special Issue Innovative Laser Medicine and Traditional Acupuncture Therapy)
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Abstract

Background: In our practice, Platelet Rich Plasma (PRP) injections effectively reduce pain in most, but not all, arthritic patients. When PRP treatment fails, joint replacement surgery is often the only good alternative. Surface Low-Level-Laser-Therapy (LLLT) has not been helpful for osteoarthrosis in our experience. We hypothesized that intra-articular laser (IAL) treatment combined with PRP would improve results in patients with prior ineffective PRP treatment. Methods: We offered Intra-articular Low-Level-Laser-Therapy (IAL) treatment simultaneously with repeat PRP injection to patients who had received no benefit from PRP alone. They were the treatment and also historical control group since all had failed PRP treatment alone. Thirty joints were treated: 22 knees, 4 hips, 2 shoulder glenohumeral joints and 2 first carpo-metacarpal (1st CMC). Results: No adverse events were seen at any time after treatment in any patient. Twenty-eight joints were available for re-evaluation: ≥ 40% improvement was seen in 46% (6 months), 32% (12 months) and 32% (24 months) post-treatment. Mean SANE scores improved significantly at 1 and 2 years. Thirteen patients failed treatment and had joint replacement. Conclusions: PRP with IAL allowed avoidance of surgery and good pain control at least two years post-treatment in nearly half of patients who had failed PRP treatment alone. View Full-Text
Keywords: platelet rich plasma; low level laser; osteoarthrosis; intra-articular laser platelet rich plasma; low level laser; osteoarthrosis; intra-articular laser
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Prodromos, C.C.; Finkle, S.; Dawes, A.; Dizon, A. Intra-Articular Laser Treatment Plus Platelet Rich Plasma (PRP) Significantly Reduces Pain in Many Patients Who Had Failed Prior PRP Treatment. Medicines 2019, 6, 75.

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