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Pilot Studies on Two Complementary Bath Products for Atopic Dermatitis Children: Pine-Tar and Tea

1
Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong 00852, China
2
Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong 00852, China
*
Author to whom correspondence should be addressed.
Medicines 2019, 6(1), 8; https://doi.org/10.3390/medicines6010008
Received: 26 September 2018 / Revised: 24 December 2018 / Accepted: 28 December 2018 / Published: 8 January 2019
(This article belongs to the Special Issue Safety of Complementary Medicines)
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Abstract

Background: Few standardized bath product clinical trials were performed for atopic dermatitis patients. Pine-tar and green tea extracts are plant-derived products that have been described as having anti-allergic effects which may reduce AD disease severity. Methods: The efficacy of two complementary bath products was studied and compared. Efficacy and acceptability of the bath products were measured by patient general acceptability of treatment (GAT: very good, good, fair or poor), disease severity (SCORAD: SCoring Atopic Dermatitis), quality of life (CDLQI: Children Dermatology Life Quality Index), and pertinent clinical parameters were measured before and after four weeks of treatment. Sample size calculations for further clinical trials were performed. In one group, nine AD patients were subjected to bathing with a pine-tar bath oil for 10–15 min daily for four weeks. In another group, 20 AD subjects bathed with a teabag containing green tea extracts for four weeks. Results: Significant improvements in clinical- and patient-orientated parameters were found in the pine-tar bathing group, but not the tea-bag bathing group. Both groups reported very good/good GAT on the studied products. Teabag bathing was considered not efficacious for further clinical trials. Conclusions: The pilot studies provided preliminary data on the efficacy of pine tar bath oil. We do not document a significant efficacy for bathing with tea extracts. Bathing with pine-tar is potentially a complementary topical treatment with good patient acceptance and adherence, but further evidence-based research for its recommendations is needed. View Full-Text
Keywords: atopic dermatitis; bath; pine-tar; green tea extracts; quality of life; sample-size calculation atopic dermatitis; bath; pine-tar; green tea extracts; quality of life; sample-size calculation
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Hon, K.L.; Ng, W.G.G.; Kung, J.S.C.; Leung, P.C.; Leung, T.F. Pilot Studies on Two Complementary Bath Products for Atopic Dermatitis Children: Pine-Tar and Tea. Medicines 2019, 6, 8.

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