Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches
School of Engineering, Ulster University, Jordanstown, Northern Ireland BT37 0QB, UK
*
Author to whom correspondence should be addressed.
Academic Editor: James D. Adams
Medicines 2017, 4(3), 48; https://doi.org/10.3390/medicines4030048
Received: 22 May 2017 / Revised: 28 June 2017 / Accepted: 28 June 2017 / Published: 30 June 2017
The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse.
View Full-Text
Keywords:
smart patches; methyl salicylate; toxicity; microneedle; transdermal
▼
Show Figures
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
MDPI and ACS Style
Anderson, A.; McConville, A.; Fanthorpe, L.; Davis, J. Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches. Medicines 2017, 4, 48. https://doi.org/10.3390/medicines4030048
AMA Style
Anderson A, McConville A, Fanthorpe L, Davis J. Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches. Medicines. 2017; 4(3):48. https://doi.org/10.3390/medicines4030048
Chicago/Turabian StyleAnderson, Ashleigh; McConville, Aaron; Fanthorpe, Laura; Davis, James. 2017. "Salicylate Poisoning Potential of Topical Pain Relief Agents: From Age Old Remedies to Engineered Smart Patches" Medicines 4, no. 3: 48. https://doi.org/10.3390/medicines4030048
Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.
Search more from Scilit