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Methylmercury Exposure and Developmental Outcomes in Tohoku Study of Child Development at 18 Months of Age

Development and Environmental Medicine, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan
Environmental Health Section, Department of Environmental Science and Epidemiology, National Institute for Minamata Disease, Kumamoto 867-0008, Japan
Department of Environmental Health Sciences, Akita University Graduate School of Medicine, Akita 010-8502, Japan
Environmental Health Science, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan
Authors to whom correspondence should be addressed.
These authors contributed equally to this work.
Toxics 2018, 6(3), 49;
Received: 29 July 2018 / Revised: 14 August 2018 / Accepted: 18 August 2018 / Published: 21 August 2018
(This article belongs to the Special Issue Mercury and Methylmercury Toxicology and Risk Assessment)
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Seafood is an important component in a healthy diet and may contain methylmercury or other contaminants. It is important to recognize the risks and benefits of consuming seafood. A longitudinal prospective birth cohort study has been conducted to clarify the effects of neurotoxicants on child development—the Tohoku Study of Child Development (TSCD) in Japan. TSCD comprises two cohorts; a polychlorinated biphenyls (PCB) cohort (urban area) and a methylmercury cohort (coastal area). Our previous results from the coastal area showed prenatal methylmercury exposure affected psychomotor development in 18-month-olds, and boys appear to be more vulnerable to the exposure than girls. In this report, we have added the urban area cohort and we reanalyzed the impact of prenatal exposure to methylmercury, which gave the same results as before. These findings suggest prenatal exposure to low levels methylmercury may have adverse effects on child development, especially in boys. View Full-Text
Keywords: methylmercury; prenatal exposure; child development methylmercury; prenatal exposure; child development

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Tatsuta, N.; Nakai, K.; Sakamoto, M.; Murata, K.; Satoh, H. Methylmercury Exposure and Developmental Outcomes in Tohoku Study of Child Development at 18 Months of Age. Toxics 2018, 6, 49.

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