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Volume 13
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10.3390/toxics13090722
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This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Article

DALYs-Based Health Risk Assessment and Key Influencing Factors of PM2.5-Bound Metals in Typical Pollution Areas of Northern China

by
Ting Zhao
1,
Kai Qu
2,
Fenghua Ma
3,
Yuhan Liang
1,
Ziquan Wang
1,
Jieyu Liu
1,
Hao Liang
1,
Min Wei
3,
Houfeng Liu
3,* and
Pingping Wang
1,*
1
School of Public Health, Shandong University, No. 44-1 Wenhua Road West, Jinan 250012, China
2
Shandong Provincial Eco-Environment Monitoring Center, Jinan 250101, China
3
College of Geography and Environment, Shandong Normal University, No. 88 Wenhua Road East, Jinan 250014, China
*
Authors to whom correspondence should be addressed.
Toxics 2025, 13(9), 722; https://doi.org/10.3390/toxics13090722
Submission received: 18 July 2025 / Revised: 14 August 2025 / Accepted: 27 August 2025 / Published: 28 August 2025
(This article belongs to the Section Air Pollution and Health)
Versions Notes

Abstract

The health risks of PM2.5-bound metals highlight the need for burden assessment, metal prioritization, and key factor analysis to support effective air quality management, yet relevant studies remain limited. Shandong Province is one of the most polluted regions in northern China, providing an ideal setting for this investigation. We monitored 17 PM2.5-bound metals for three years across Shandong, China and performed disease burden assessment based on disability-adjusted life years (DALYs). Furthermore, key influencing factors contributing to high-hazard metals were identified through explainable machine learning. The results showed that PM2.5-bound metal concentrations were generally higher in inland areas than in coastal regions, with Ni concentrations elevated in coastal areas. K, Ca, Zn, and Mn exhibited the highest three-year average concentrations among the metals, while Cr averaged 6.12 ng/m3, significantly exceeding the recommended annual limit of 0.025 ng/m3 set by Chinese Ambient Air Quality Standards. Jinan carried the greatest burden at 4.67 DALYs per 1000 people, followed by Zibo (3.78), Weifang (2.98), and Rizhao (2.80). CKD, interstitial pneumonia, and chronic respiratory diseases account for the highest DALYs from PM2.5-bound metals in Shandong Province. Industrial emissions are the largest contributors to the disease burden (>34%), with Cr, Cd, and Pb as the primary contributing metals requiring priority control. Fractional vegetation cover was identified as the key factor contributing to the reduction in their concentrations. These results underscore that prioritizing the regulation of industrial combustion, particularly concerning Cr, Cd, and Pb, and enhancing fractional vegetation cover could reduce disease burden and provide public health benefits.
Keywords: PM2.5-bound metals; health risk assessment; disease burden; XGBoost PM2.5-bound metals; health risk assessment; disease burden; XGBoost

Share and Cite

MDPI and ACS Style

Zhao, T.; Qu, K.; Ma, F.; Liang, Y.; Wang, Z.; Liu, J.; Liang, H.; Wei, M.; Liu, H.; Wang, P. DALYs-Based Health Risk Assessment and Key Influencing Factors of PM2.5-Bound Metals in Typical Pollution Areas of Northern China. Toxics 2025, 13, 722. https://doi.org/10.3390/toxics13090722

AMA Style

Zhao T, Qu K, Ma F, Liang Y, Wang Z, Liu J, Liang H, Wei M, Liu H, Wang P. DALYs-Based Health Risk Assessment and Key Influencing Factors of PM2.5-Bound Metals in Typical Pollution Areas of Northern China. Toxics. 2025; 13(9):722. https://doi.org/10.3390/toxics13090722

Chicago/Turabian Style

Zhao, Ting, Kai Qu, Fenghua Ma, Yuhan Liang, Ziquan Wang, Jieyu Liu, Hao Liang, Min Wei, Houfeng Liu, and Pingping Wang. 2025. "DALYs-Based Health Risk Assessment and Key Influencing Factors of PM2.5-Bound Metals in Typical Pollution Areas of Northern China" Toxics 13, no. 9: 722. https://doi.org/10.3390/toxics13090722

APA Style

Zhao, T., Qu, K., Ma, F., Liang, Y., Wang, Z., Liu, J., Liang, H., Wei, M., Liu, H., & Wang, P. (2025). DALYs-Based Health Risk Assessment and Key Influencing Factors of PM2.5-Bound Metals in Typical Pollution Areas of Northern China. Toxics, 13(9), 722. https://doi.org/10.3390/toxics13090722

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