Sub-Chronic Difenoconazole Exposure Induced Gut Microbiota Dysbiosis in Mice
Abstract
:1. Introduction
2. Methods and Materials
2.1. Chemicals and Experimental Animal Husbandry
2.2. Histopathological Analysis
2.3. Colonic RNA Extraction and Real-Time qPCR
2.4. 16S rRNA Analysis
2.5. Statistical Analysis
3. Results
3.1. Exposure to DIF Affected the Colonic Mucus Expression
3.2. Exposure to DIF Affected the Gut Microbiota Composition
3.3. Data Analysis from 16S rRNA Sequencing
3.4. Differential Genera after DIF Exposure
4. Discussion
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Acknowledgments
Conflicts of Interest
References
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Bao, Z.; Wang, W.; Wang, X.; Qian, M.; Jin, Y. Sub-Chronic Difenoconazole Exposure Induced Gut Microbiota Dysbiosis in Mice. Toxics 2022, 10, 34. https://doi.org/10.3390/toxics10010034
Bao Z, Wang W, Wang X, Qian M, Jin Y. Sub-Chronic Difenoconazole Exposure Induced Gut Microbiota Dysbiosis in Mice. Toxics. 2022; 10(1):34. https://doi.org/10.3390/toxics10010034
Chicago/Turabian StyleBao, Zhiwei, Weitao Wang, Xiaofang Wang, Mingrong Qian, and Yuanxiang Jin. 2022. "Sub-Chronic Difenoconazole Exposure Induced Gut Microbiota Dysbiosis in Mice" Toxics 10, no. 1: 34. https://doi.org/10.3390/toxics10010034