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Open AccessArticle

Simple and Efficient Green Extraction of Steviol Glycosides from Stevia rebaudiana Leaves

1
Department of Chemistry, Faculty of Experimental Sciences, University of Huelva, 21007 Huelva, Spain
2
International Campus of Excellence CeiA3, University of Huelva, 21007 Huelva, Spain
*
Authors to whom correspondence should be addressed.
Present address: Biomarkers & Nutrimetabolomics Laboratory, Department of Nutrition, Food Sciences and Gastronomy, Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Foods 2019, 8(9), 402; https://doi.org/10.3390/foods8090402
Received: 5 August 2019 / Revised: 23 August 2019 / Accepted: 6 September 2019 / Published: 11 September 2019
(This article belongs to the Special Issue Natural Food Additives: From Source to Application)
The food industry has currently shown great interest in alternative sweeteners to sugars with the aim of producing healthier products. In light of this, steviol glycosides are natural low-caloric sweeteners present in Stevia rebaudiana, which have additionally been described as bioactive components with potential therapeutic properties. In this work, a green method for the extraction of steviol glycosides from stevia leaves was optimized by applying a factorial screening design of five variables (time, temperature, agitation, grinding, and sample–solvent ratio) and the subsequent response surface design of Box-Behnken. The optimized extraction method allows for the recovery of stevia sweeteners in a simple and efficient manner by using tap water as the extractant, without the application of an auxiliary energy source to reduce costs, thus representing an interesting strategy for their industrial-scale production. View Full-Text
Keywords: steviol glycosides; green extraction; stevia leaves; stevioside; rebaudioside A steviol glycosides; green extraction; stevia leaves; stevioside; rebaudioside A
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López-Carbón, V.; Sayago, A.; González-Domínguez, R.; Fernández-Recamales, Á. Simple and Efficient Green Extraction of Steviol Glycosides from Stevia rebaudiana Leaves. Foods 2019, 8, 402.

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