Next Article in Journal
Case Reports in Pediatric Dentistry Journals: A Systematic Review about Their Effect on Impact Factor and Future Investigations
Previous Article in Journal
Survival of a Maxillary Incisor in an Adolescent Male 16 Years after Its Delayed Replantation
Previous Article in Special Issue
Early Diagnosis on Oral and Potentially Oral Malignant Lesions: A Systematic Review on the VELscope® Fluorescence Method
Open AccessCase Report

Pulmonary Nodule in a Patient with Oral and Lung Cancer: Cryptococcus Infection

Department of Oral and Maxillofacial Surgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan
*
Author to whom correspondence should be addressed.
Dent. J. 2019, 7(4), 102; https://doi.org/10.3390/dj7040102
Received: 24 August 2019 / Revised: 15 October 2019 / Accepted: 17 October 2019 / Published: 23 October 2019
(This article belongs to the Special Issue Oral Cancer: Diagnosis and Treatment)
Pulmonary nodules are frequently considered to be a metastatic disease or primary lung tumors in oral cancer patients. We present a case of pulmonary cryptococcosis in a 68-year-old man with oral and lung cancer. This lung cancer was treated with thoracoscopic resection of the right inferior lobe and mediastinal lymph node dissection. Lower gingival cancer was treated with a mandibulectomy, neck dissection, and reconstruction after chemoradiotherapy. A 20 mm cavitary nodule appeared at the left lung S6 one-month after surgery, during post-operative computed tomography. Thoracoscopic partial resection of the left inferior lobe was performed under the suspicion of lung metastasis. Pathology results revealed a pseudo-epithelial granuloma with necrosis and many yeast-shaped fungi with capsules. A pathological diagnosis of Cryptococcus infection was made. The patient was prescribed the antifungal agent fosfluconazole, which was administered intravenously for 1 week and intraoral fluconazole for 12 months. No recurrence of the Cryptococcus infection has been noted after 1.5 years. View Full-Text
Keywords: pulmonary nodule; oral cancer; lung cancer; Cryptococcus infection; antifungal agent pulmonary nodule; oral cancer; lung cancer; Cryptococcus infection; antifungal agent
Show Figures

Figure 1

MDPI and ACS Style

Yamagata, K.; Hirano, C.; Kanno, N.; Uchida, F.; Fukuzawa, S.; Yanagawa, T.; Bukawa, H. Pulmonary Nodule in a Patient with Oral and Lung Cancer: Cryptococcus Infection. Dent. J. 2019, 7, 102.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop