Effect of Dietary Fiber on the Composition of the Murine Dental Microbiome
AbstractThe oral cavity houses a diverse consortium of microorganisms, heavily influenced by host diet, that can mediate dental health and disease. While the impact of dietary carbohydrates to the dental microbiome has been well-documented, the effect of fiber as a mechanical influence on the dental microbiome is unexplored. We performed 16S rRNA gene analysis to investigate the response of the dental microbiome to the presence of increased fiber in terms of microbial taxonomic abundance and diversity. Dental microbial community structure was significantly different in mice fed a diet supplemented with increased fiber and/or sugar. Fiber significantly affected measures of beta diversity at the phylum and genus levels, and a strong interactive effect on alpha diversity was observed between sugar and fiber at the phylum level. The addition of fiber also induced significant variation in relative taxonomic abundance. This study demonstrates that fiber can promote significant variations in the mouse dental microbiome. View Full-Text
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Sedghi, L.; Byron, C.; Jennings, R.; Chlipala, G.E.; Green, S.J.; Silo-Suh, L. Effect of Dietary Fiber on the Composition of the Murine Dental Microbiome. Dent. J. 2019, 7, 58.
Sedghi L, Byron C, Jennings R, Chlipala GE, Green SJ, Silo-Suh L. Effect of Dietary Fiber on the Composition of the Murine Dental Microbiome. Dentistry Journal. 2019; 7(2):58.Chicago/Turabian Style
Sedghi, Lea; Byron, Craig; Jennings, Ryan; Chlipala, George E.; Green, Stefan J.; Silo-Suh, Laura. 2019. "Effect of Dietary Fiber on the Composition of the Murine Dental Microbiome." Dent. J. 7, no. 2: 58.
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