Unconventional Anticancer Metallodrugs and Strategies to Improve Their Pharmacological Profile
References
- Casini, A.; Vessières, A.; Meier-Menches, M. (Eds.) Metal-Based Anticancer Agents, 1st ed.; Metallobiology Series No 14; Royal Society of Chemistry: Cambridge, UK, 2019. [Google Scholar]
- Sigel, A.; Sigel, H.; Freisinger, E.; Sigel, R.K.O. (Eds.) Metallodrugs: Development and Action of Anticancer Agents; Metal Ions in Life Sciences Series No 18; Walter de Gruyter GmbH: Berlin, Germany, 2018. [Google Scholar]
- Engliner, B.; Pirker, C.; Heffeter, P.; Terenzi, A.; Kowol, C.R.; Keppler, B.K.; Berger, W. Metal Drugs and the Anticancer Immune Response. Chem. Rev. 2019, 119, 1519–1624. [Google Scholar] [CrossRef] [PubMed]
- Monro, S.; Colon, K.L.; Yin, H.; Roque, J.; Konda, P.; Gujar, S.; Thummel, R.P.; Lilge, L.; Cameron, C.G.; McFarland, S.A. Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433. Chem. Rev. 2019, 119, 797–828. [Google Scholar] [CrossRef] [PubMed]
- Kenny, R.G.; Marmion, C. Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens? Chem. Rev. 2019, 119, 1058–1137. [Google Scholar] [CrossRef] [PubMed]
- Wang, X.; Wang, X.; Jin, S.; Muhammad, N.; Guo, Z. Stimuli-Responsive Therapeutic Metallodrugs. Chem. Rev. 2019, 119, 1138–1192. [Google Scholar] [CrossRef] [PubMed]
- Sirolimus and Auranofin in Treating Patients with Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer. Available online: https://clinicaltrials.gov/ct2/show/NCT01737502 (accessed on 1 July 2109).
- Auranofin in Treating Patients with Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer’. Available online: https://clinicaltrials.gov/ct2/show/NCT01747798 (accessed on 1 July 2109).
- Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or Gemcitabine. Available online: https://clinicaltrials.gov/ct2/show/NCT03714555 (accessed on 1 July 2109).
- Health Canada Grants ITA Approval to Commence Phase II Clinical Study. Available online: https://theralase.com/pressrelease/health-canada-grants-ita-approval-to-commence-phase-ii-clinical-study/ (accessed on 1 July 2109).
- Coverdale, J.P.C.; Laroiya-McCarron, T.; Romero-Canelón, I. Designing Ruthenium Anticancer Drug: What Have We Learnt from the Key Drug Candidates? Inorganics 2019, 7, 31. [Google Scholar] [CrossRef]
- Gaur, K.; Vázquez-Salgado, A.M.; Duran-Camacho, G.; Domínguez-Martínez, I.; Benjamin-Rivera, J.A.; Fernández-Vega, L.; Carmona Sarabia, L.; Cruz Gracia, A.; Pérez-Deliz, F.; Méndez Román, J.A.; et al. Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy. Inorganics 2018, 6, 126. [Google Scholar] [CrossRef]
- Poursharifi, M.; Wlodarczyk, M.T.; Mieszawska, A.J. Nano-Based Systems and Biomecremules as Carriers for Metallodrugs in Anticancer Therapy. Inorganics 2019, 7, 2. [Google Scholar] [CrossRef]
- Komeda, S.; Uemura, M.; Yoneyama, H.; Harusawa, S.; Hiramoto, K. In Vitro Cytotoxicity and In Vivo Antitumor Efficacy of Tetrazolato-Bridged Dinuclear Platinum(II) Complexes with a Bulky Substituent at Tetrazole C5. Inorganics 2019, 7, 5. [Google Scholar] [CrossRef]
- Cubo, L.; Parro, T.; Carnero, A.; Salassa, L.; Matesanz, A.I.; Quiroga, A.G. Synthesis, Reactivity Studies, and Cytotoxicity of Two trans-Iodidoplatinum(II) Complexes. Does Photoactivation Work? Inorganics 2018, 6, 127. [Google Scholar] [CrossRef]
- Colina-Vega, L.; Oliveira, K.M.; Cunha, B.N.; Cominetti, M.R.; Navarro, M.; Azevedo Batista, A. Anti-Proliferative and Anti-Migration Activity of Arene-Ruthenium(II) Comeplex with Azole Therapeutic Agents. Inorganics 2018, 6, 132. [Google Scholar] [CrossRef]
- Caviccioli, M.; Monteiro Lino Zaballa, A.; de Paula, Q.A.; Bach Prieto, M.; Columbano Oliveira, C.; Civitareale, P.; Ciriolo, M.R.; Da Costa Ferreira, A.M. Oxidative Assets Toward Biomolecules and Cytotoxicity of New Oxindolimine-Copper(II) and Zinc(II) Complexes. Inorganics 2019, 7, 12. [Google Scholar] [CrossRef]
- Goitia, H.; Villacampa, M.D.; Laguna, A.; Gimeno, M.C. Cytotoxic Gold(I) Complexes with Amidophosphine Ligands Containing Thiophene Moieties. Inorganics 2019, 7, 13. [Google Scholar] [CrossRef]
- Beaton, J.; Farrell, N.P. Investigation of 1-Methylcytosine as a Ligand in Gold(III) Complexes: Synthesis and Protein Interactions. Inorganics 2019, 7, 1. [Google Scholar] [CrossRef]
- Aikman, B.; Wenzel, M.N.; Mósca, A.F.; de Almeida, A.; Klooster, W.T.; Coles, S.J.; Soveral, G.; Casini, A. Gold(III) Pyridine-Benzimidazole Complexes as Aquaglyceroporin Inhibitors and Antiproliferative Agents. Inorganics 2018, 6, 123. [Google Scholar] [CrossRef]
- Klose, M.H.M.; Theiner, S.; Varbanov, H.P.; Hoefer, D.; Oichler, V.; Galanski, M.; Meier-Menches, S.M.; Keppler, B.K. Development and Validation of Liquid Chromatography-Based Methods to Assess the Lipophilicity of Cytotoxic Platinum(IV) Complexes. Inorganics 2018, 6, 130. [Google Scholar] [CrossRef]
- Alonso-de Castro, S.; Ruggiero, E.; Lekuona Fernández, A.; Cossío, U.; Baz, Z.; Otaegui, D.; Gómez-Vallejo, V.; Padro, D.; Llop, J.; Salassa, L. Functionalizing NaGdF4:Yb,Er Upconverting Nanoparticles with Bone-Targeting Phosphonate Ligands: Imaging and In Vivo Biodistribution. Inorganics 2019, 7, 60. [Google Scholar] [CrossRef]
© 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Contel, M. Unconventional Anticancer Metallodrugs and Strategies to Improve Their Pharmacological Profile. Inorganics 2019, 7, 88. https://doi.org/10.3390/inorganics7070088
Contel M. Unconventional Anticancer Metallodrugs and Strategies to Improve Their Pharmacological Profile. Inorganics. 2019; 7(7):88. https://doi.org/10.3390/inorganics7070088
Chicago/Turabian StyleContel, María. 2019. "Unconventional Anticancer Metallodrugs and Strategies to Improve Their Pharmacological Profile" Inorganics 7, no. 7: 88. https://doi.org/10.3390/inorganics7070088
APA StyleContel, M. (2019). Unconventional Anticancer Metallodrugs and Strategies to Improve Their Pharmacological Profile. Inorganics, 7(7), 88. https://doi.org/10.3390/inorganics7070088