Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends
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Department of Chemistry and Biochemistry, Mendel University in Brno, Zemedelska 1, CZ-613 00 Brno, Czech Republic
2
Central European Institute of Technology, Brno University of Technology, Purkynova 123, CZ-612 00 Brno, Czech Republic
*
Author to whom correspondence should be addressed.
Processes 2020, 8(12), 1636; https://doi.org/10.3390/pr8121636
Received: 18 November 2020
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Revised: 9 December 2020
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Accepted: 10 December 2020
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Published: 11 December 2020
(This article belongs to the Special Issue Application of Carbon-Based Nanocomposites in Bioengineering and Biomedicine)
The development of an advanced and efficient drug delivery system with significant improvement in its efficacy and enhanced therapeutic value is one of the critical challenges in modern medicinal biology. The integration of nanomaterial science with molecular and cellular biology has helped in the advancement and development of novel drug delivery nanocarrier systems with precision and decreased side effects. The design and synthesis of nanocarriers using graphene oxide (GO) have been rapidly growing over the past few years. Due to its remarkable physicochemical properties, GO has been extensively used in efforts to construct nanocarriers with high specificity, selectivity, and biocompatibility, and low cytotoxicity. The focus of this review is to summarize and address recent uses of GO-based nanocarriers and the improvements as efficient drug delivery systems. We briefly describe the concepts and challenges associated with nanocarrier systems followed by providing critical examples of GO-based delivery of drug molecules and genes. Finally, the review delivers brief conclusions on the current understanding and prospects of nanocarrier delivery systems.
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Keywords:
graphene oxide; graphene; nanocarrier; drug delivery; nanomaterials; cancer drug; gene delivery
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MDPI and ACS Style
Mukherjee, S.; Bytesnikova, Z.; Ashrafi, A.M.; Adam, V.; Richtera, L. Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends. Processes 2020, 8, 1636. https://doi.org/10.3390/pr8121636
AMA Style
Mukherjee S, Bytesnikova Z, Ashrafi AM, Adam V, Richtera L. Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends. Processes. 2020; 8(12):1636. https://doi.org/10.3390/pr8121636
Chicago/Turabian StyleMukherjee, Soumajit, Zuzana Bytesnikova, Amir M. Ashrafi, Vojtech Adam, and Lukas Richtera. 2020. "Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends" Processes 8, no. 12: 1636. https://doi.org/10.3390/pr8121636
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