Fatigue and Quality of Life in Children with Chronic Kidney Disease
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
2.2. Procedures
2.3. Instruments
2.4. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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CKD 2–4 10 Patients | CKD 5D 13 Patients | KTx 7 Patients | p | |
---|---|---|---|---|
Demographic data | ||||
Age | 11.5 (7–18) | 13 (7–18) | 14 (8–18) | 0.308 |
Sex (male) | 6 (60%) | 8 (61.5%) | 5 (71.4%) | 0.877 |
Inherited kidney disease | 6 (60%) | 11 (84.6%) | 6 (85.7%) | 0.312 |
Residence place (urban) | 7 (70%) | 6 (46.1%) | 4 (57.1%) | 0.520 |
Parental education level | 0.212 | |||
Elementary school | 1 (10%) | 5 (38.4%) | 1 (14.2%) | |
High school | 3 (30%) | 6 (46.2%) | 3 (42.9%) | |
University Degree | 6 (60%) | 2 (15.4%) | 3 (42.9%) | |
Fatigue scores | ||||
General Fatigue | 89.6 (45.8–100) | 62.5 (45.8–100) | 83.3 (58.3–100) | 0.076 |
Sleep/Rest Fatigue | 72.9 (66.6–100) | 50 (29.2–79.2) | 50 (33.3–91.6) | 0.071 |
Cognitive Fatigue | 83.4 (41.7–100) | 66.7 (25–87.5) | 58.3 (50–100) | 0.215 |
Total Fatigue | 84.7 (55.5–93.1) | 59.7 (36.1–85.8) | 69.4 (47.2–93) | 0.052 |
Low Fatigue scores | ||||
General Fatigue | 1 (10%) | 6 (46.2%) | 0 (0%) | 0.032 |
Sleep/Rest Fatigue | 0 (0%) | 7 (53.8%) | 4 (57.1%) | 0.013 |
Cognitive Fatigue | 1 (10%) | 3 (23.1%) | 3 (42.9%) | 0.289 |
Total Fatigue | 0 (0%) | 4 (30.8%) | 1 (14.3%) | 0.143 |
HRQoL scores | ||||
Physical Functioning | 87.5 (43.75–100) | 75 (28.1–100) | 78.1 (40.6–87.5) | 0.210 |
Emotional Functioning | 77.5 (30–100) | 55 (20–95) | 65 (25–95) | 0.324 |
Social Functioning | 82.5 (50–100) | 70 (35–100) | 70 (55–85) | 0.173 |
School Functioning | 77.5 (60–90) | 60 (17–100) | 60 (15–90) | 0.209 |
Total HRQoL | 87 (48.9–91.7) | 67.4 (35.9–93.5) | 71.7 (45.7–80.4) | 0.126 |
Low HRQoL scores | ||||
Physical Functioning | 1 (10%) | 4 (30.8%) | 1 (14.3%) | 0.425 |
Emotional Functioning | 2 (20%) | 5 (38.5%) | 3 (42.9%) | 0.538 |
Social Functioning | 1 (10%) | 3 (23.1%) | 0 (0%) | 0.326 |
School Functioning | 0 (0%) | 5 (38.5%) | 3 (42.9%) | 0.064 |
Total HRQoL | 1 (10%) | 3 (23.1%) | 1 (14.3%) | 0.693 |
Physical Functioning | Emotional Functioning | Social Functioning | School Functioning | Total HRQoL | |
---|---|---|---|---|---|
General Fatigue | rs = 0.434, p = 0.017 | rs = 0.409, p = 0.025 | rs = 0.319, p = 0.086 | rs = 0.417, p = 0.019 | rs = 0.504, p = 0.004 |
Sleep/Rest Fatigue | rs = 0.481, p = 0.007 | rs = 0.302, p = 0.105 | rs = 0.459, p = 0.011 | rs = 0.458, p = 0.011 | rs = 0.503, p = 0.005 |
Cognitive Fatigue | rs = 0.565, p = 0.001 | rs = 0.455, p = 0.011 | rs = 0.513, p = 0.004 | rs = 0.564, p = 0.001 | rs = 0.654, p < 0.001 |
Total Fatigue | rs = 0.564, p = 0.001 | rs = 0.414, p = 0.023 | rs = 0.498, p = 0.005 | rs = 0.548, p = 0.002 | rs = 0.625, p < 0.001 |
Physical Functioning | Emotional Functioning | Social Functioning | School Functioning | Total HRQoL | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
>50 24 pts | ≤50 6 pts | p | >50 20 pts | ≤50 10 pts | p | >50 26 pts | ≤50 4 pts | p | >50 22 pts | ≤50 8 pts | p | >50 25 pts | ≤50 5 pts | p | |
General Fatigue | 4 (16.7%) | 3 (50%) | 0.120 | 3 (15%) | 4 (40%) | 0.181 | 4 (15.4%) | 3 (75%) | 0.031 | 4 (18.2%) | 3 (37.5%) | 0.345 | 3 (12%) | 4 (80%) | 0.006 |
Sleep/ Rest Fatigue | 6 (25%) | 5 (83.3%) | 0.016 | 5 (25%) | 6 (60%) | 0.108 | 9 (34.6%) | 2 (50%) | 0.611 | 4 (18.2%) | 7 (87.5%) | 0.001 | 7 (28%) | 4 (80%) | 0.047 |
Cognitive Fatigue | 4 (16.7%) | 3 (50%) | 0.120 | 3 (15%) | 4 (40%) | 0.181 | 6 (23.1%) | 1 (25%) | 1 | 1 (4.5%) | 6 (75%) | <0.001 | 4 (16%) | 3 (60%) | 0.068 |
Total Fatigue | 1 (4.2%) | 4 (66.7%) | 0.003 | 1 (5%) | 4 (40%) | 0.031 | 3 (11.5%) | 2 (50%) | 0.119 | 1 (4.5%) | 4 (50%) | 0.011 | 1 (4%) | 4 (80%) | 0.001 |
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Karava, V.; Goutou, S.; Dotis, J.; Kondou, A.; Charela, E.; Dadoudi, O.; Eleftheriadis, T.; Stefanidis, I.; Printza, N. Fatigue and Quality of Life in Children with Chronic Kidney Disease. Children 2022, 9, 1414. https://doi.org/10.3390/children9091414
Karava V, Goutou S, Dotis J, Kondou A, Charela E, Dadoudi O, Eleftheriadis T, Stefanidis I, Printza N. Fatigue and Quality of Life in Children with Chronic Kidney Disease. Children. 2022; 9(9):1414. https://doi.org/10.3390/children9091414
Chicago/Turabian StyleKarava, Vasiliki, Sofia Goutou, John Dotis, Antonia Kondou, Evangelia Charela, Olympia Dadoudi, Theodoros Eleftheriadis, Ioannis Stefanidis, and Nikoleta Printza. 2022. "Fatigue and Quality of Life in Children with Chronic Kidney Disease" Children 9, no. 9: 1414. https://doi.org/10.3390/children9091414