Allergen Tests of Fruit Sensitization Involving Children with Allergic Diseases
Abstract
:1. Introduction
2. Materials and Methods
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Negative Specific IgE to Pineapple | Positive Specific IgE to Pineapple | p | Negative Specific IgE to Kiwi | Positive Specific IgE to Kiwi | p | |
Number | 5323 | 628 | 6124 | 696 | ||
Age (years) | 5.4 ± 3.9 | 5.2 ± 3.4 | 0.126 | 5.8 ± 4.3 | 5.1 ± 3.8 | <0.001 * |
Sex | 0.193 | 0.862 | ||||
Female | 2145 | 270 | 2478 | 284 | ||
Male | 3178 | 358 | 3646 | 412 | ||
Total IgE (U/mL) | 471.4 ± 673.7 | 1132.2 ± 1194.6 | <0.001 * | 442.5 ± 626 | 1305.8 ± 1359.5 | <0.001 * |
Logarithmic IgE | 2.3 ± 0.6 | 2.8 ± 0.5 | <0.001 * | 2.3 ± 0.6 | 2.9 ± 0.5 | <0.001 * |
Asthma/rhinitis | 53.1% | 50.2% | 0.159 | 48.5% | 48.4% | 0.956 |
Asthma/dermatitis | 12.3% | 19.8% | <0.001 * | 11.2% | 19.0% | <0.001 * |
Dermatitis | 29.9% | 48.1% | <0.001 * | 27.5% | 48.1% | <0.001 * |
Dermatitis/rhinitis | 24.8% | 43.0% | <0.001 * | 22.1% | 42.0% | <0.001 * |
Asthma/dermatitis/rhinitis | 10.9% | 18.5% | <0.001 * | 9.8% | 17.7% | <0.001 * |
Asthma | 58.5% | 54.9% | 0.090 | 54.7% | 53.7% | 0.633 |
Rhinitis | 86.7% | 88.7% | 0.150 | 84.4% | 86.5% | 0.148 |
Negative specific IgE to banana | Positive specific IgE to banana | p | Negative specific IgE to papaya | Positive specific IgE to papaya | p | |
Number | 1190 | 134 | 827 | 64 | ||
Age (years) | 6.9 ± 5.5 | 4.9 ± 4.5 | <0.001 * | 7.1 ± 5.5 | 4.7 ± 4.3 | <0.001 * |
Sex | 0.472 | 0.392 | ||||
Female | 468 | 57 | 292 | 26 | ||
Male | 722 | 77 | 535 | 38 | ||
Total IgE (U/mL) | 470.5 ± 678.1 | 1287.3 ± 1927 | <0.001 * | 422.4 ± 601.4 | 1165.7 ± 1001.4 | <0.001 * |
Logarithmic IgE | 2.3 ± 0.6 | 2.9 ± 0.5 | <0.001 * | 2.2 ± 0.7 | 2.9 ± 0.5 | <0.001 * |
Asthma/rhinitis | 28.1% | 38.8% | 0.010 * | 30.2% | 32.8% | 0.665 |
Asthma/dermatitis | 6.1% | 13.4% | 0.002 * | 5.2% | 18.8% | <0.001 * |
Dermatitis | 21.5% | 38.8% | <0.001 * | 15.7% | 51.6% | <0.001 * |
Dermatitis/rhinitis | 10.7% | 23.1% | <0.001 * | 10.6% | 35.9% | <0.001 * |
Asthma/dermatitis/rhinitis | 4.3% | 10.5% | 0.002 * | 4.2% | 14.1% | 0.003 * |
Asthma | 41.6% | 50% | 0.062 | 37.7% | 53.1% | 0.015 |
Rhinitis | 64.3% | 69.4% | 0.240 | 73.4% | 65.6% | 0.178 |
log IgE | ||||
---|---|---|---|---|
Cutoff | Sensitivity | Specificity | IgE U/mL | |
Pineapple | 2.2 | 0.9 | 0.5 | 158.5 |
Kiwi | 2.7 | 0.7 | 0.7 | 501.2 |
Banana | 2.5 | 0.8 | 0.6 | 316.2 |
Papaya | 2.4 | 0.8 | 0.6 | 251.2 |
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Chang, L.-S.; Chang, H.-Y.; Yang, Y.-H.; Lee, Z.-M.; Guo, M.M.-H.; Huang, Y.-H.; Kuo, H.-C. Allergen Tests of Fruit Sensitization Involving Children with Allergic Diseases. Children 2022, 9, 470. https://doi.org/10.3390/children9040470
Chang L-S, Chang H-Y, Yang Y-H, Lee Z-M, Guo MM-H, Huang Y-H, Kuo H-C. Allergen Tests of Fruit Sensitization Involving Children with Allergic Diseases. Children. 2022; 9(4):470. https://doi.org/10.3390/children9040470
Chicago/Turabian StyleChang, Ling-Sai, Hsin-Yu Chang, Yao-Hsu Yang, Zon-Min Lee, Mindy Ming-Huey Guo, Ying-Hsien Huang, and Ho-Chang Kuo. 2022. "Allergen Tests of Fruit Sensitization Involving Children with Allergic Diseases" Children 9, no. 4: 470. https://doi.org/10.3390/children9040470