Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design and Setting
2.2. Patients
2.3. Data Collection
2.4. Neurological Examination
2.5. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Risk | HNNE |
---|---|
Low risk | 27–33 |
Medium risk | 25.4–26.9 or 33.1–33.5 |
High risk | <25.4 or >33.5 |
Admitted Neonates (n = 453) | Newborns at 1 Month Follow-Up (n = 119) | |
---|---|---|
Males | 237 (52.3) | 65 (54.6) |
Birth weight, grams a | 2750 (1940–3180) | 2610 (1795–3055) |
Birth weight: | ||
Normal birth weight (≥2500 g) | 269 (59.4) | 62 (52.1) |
Low birth weight (1500–2499 g) | 130 (28.7) | 43 (36.1) |
Very low birth weight (1000–1499 g) | 42 (9.3) | 14 (11.8) |
Extremely low birth weight (<1000 g) | 12 (2.6) | 0 (0.0) |
Temperature at admission, °C a | 35.4 (34.7–36.1) | 35.4 (24.8–35.9) |
Temperature at admission: | ||
36.5–37.5 °C | 71 (15.7) | 16 (13.5) |
36–36.5 °C | 66 (14.6) | 13 (10.9) |
<36 °C | 316 (69.7) | 90 (75.6) |
HIV-positive mother | 35/450 (7.8) | 13/118 (11.0) |
Maternal VDRL b | 7/438 (1.6) | 1/117 (0.9) |
Apgar score at 1 min a | 5 (3–7) | 5 (2–8) |
Apgar score at 5 min a | 7 (5–10) | 8 (5–10) |
PROM c | 86 (19.0) | 22 (18.5) |
Meconium-stained amniotic fluid | 133 (29.4) | 34 (28.6) |
Maternal fever | 12 (2.6) | 2 (1.7) |
Dexamethasone: | ||
None | 414 (91.4) | 99 (84.2) |
Complete cycle (24 mg) | 26 (5.7) | 14 (11.8) |
Incomplete cycle (12 mg) | 13 (2.9) | 6 (5.0) |
Mode of delivery | ||
Spontaneous vaginal delivery | 221 (48.8) | 63 (52.9) |
Assisted vaginal delivery | 42 (9.3) | 11 (9.3) |
Caesarean section | 190 (41.9) | 45 (37.8) |
Twin pregnancy | 61/452 (13.5) | 24 (20.2) |
Birth asphyxia | 171 (37.7) | 49 (41.2) |
Respiratory distress | 308 (68.0) | 83 (69.7) |
Early-onset sepsis | 22 (4.9) | 6 (5.0) |
Late-onset sepsis | 18 (4.0) | 5 (4.2) |
Hypoglycemia | 20/428 (4.7) | 7/114 (6.1) |
Jaundice | 85 (18.8) | 29 (24.4) |
Weight loss | 10 (2.2) | 2 (1.7) |
Skin infection | 14 (3.1) | 8 (6.7) |
Major malformations or chromosomopathies d | 19 (4.2) | 2 (1.7) |
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Guadagno, C.; Cavallin, F.; Brasili, L.; Maziku, D.M.; Leluko, D.E.; Azzimonti, G.; Putoto, G.; Pietravalle, A.; Trevisanuto, D. Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study. Children 2022, 9, 352. https://doi.org/10.3390/children9030352
Guadagno C, Cavallin F, Brasili L, Maziku DM, Leluko DE, Azzimonti G, Putoto G, Pietravalle A, Trevisanuto D. Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study. Children. 2022; 9(3):352. https://doi.org/10.3390/children9030352
Chicago/Turabian StyleGuadagno, Chiara, Francesco Cavallin, Luca Brasili, Donald Micah Maziku, Dionis Erasto Leluko, Gaetano Azzimonti, Giovanni Putoto, Andrea Pietravalle, and Daniele Trevisanuto. 2022. "Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study" Children 9, no. 3: 352. https://doi.org/10.3390/children9030352
APA StyleGuadagno, C., Cavallin, F., Brasili, L., Maziku, D. M., Leluko, D. E., Azzimonti, G., Putoto, G., Pietravalle, A., & Trevisanuto, D. (2022). Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study. Children, 9(3), 352. https://doi.org/10.3390/children9030352