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Volume 9
Issue 12
10.3390/children9121810
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Review
Peer-Review Record

Ferumoxytol-Enhanced Cardiac Magnetic Resonance Angiography and 4D Flow: Safety and Utility in Pediatric and Adult Congenital Heart Disease

Children 2022, 9(12), 1810; https://doi.org/10.3390/children9121810
by Pierangelo Renella 1,2,*, Jennifer Li 1,3, Ashley E. Prosper 1, J. Paul Finn 1 and Kim-Lien Nguyen 1,3
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Children 2022, 9(12), 1810; https://doi.org/10.3390/children9121810
Submission received: 3 October 2022 / Revised: 31 October 2022 / Accepted: 14 November 2022 / Published: 24 November 2022
(This article belongs to the Special Issue Frontiers in Pediatric Cardiac Imaging)

Round 1

Reviewer 1 Report

This is a well written review covered adequate knowledge in the field, I appreciate the work.

Author Response

Thank you for your kind review of the manuscript and your feedback.

Reviewer 2 Report

Authors have nicely addressed innovations in ferumoxytol enhanced CMR in patients with congenital heart diseases. Despite the fact that recent studies are limited - involving limited number of patients- authors have gathered and present the existing literature.

I believe that authors should perform minor changes, mainly to enhance the understandability of their manuscript.

·        A table (or figure) ferumoxytol versus gadolinium should be added reporting the pros and cons of each contrast media.

·        A table with the disease- specific features that render ferumoxytol a better choice than gadolinium for CMR imaging.

Author Response

Thank you for your feedback on the manuscript. We have added the two requested Tables (Table 2 and Table 3). We have uploaded the updated Clean version of the manuscript.

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