Neuropsychological and Academic Performance in Colombian Children with Attention-Deficit Hyperactivity Disorder: A Comparative Study with a Control Group
Abstract
:1. Introduction
Method | Country | Findings | Study |
---|---|---|---|
Sample: Children aged from 6 to 13 years diagnosed with ADHD. Aim: To analyze the cognitive profiles of children with ADHD and to examine the differences between them. | Spain | In the evaluation of the two neuropsychological profiles, no significant differences were found in the index of verbal comprehension, perceptual reasoning, and total intelligence quotient/general ability index. However, the ADHD group showed lower scores than the control group in working memory. Regarding the processing speed index, the control group exhibited lower performance than the group of children with ADHD. | [35] |
Sample: Children aged 5 to 15 diagnosed with ADHD. Objective: To identify differences in neuropsychological performance between a group of children diagnosed with combined-type and inattentive-type ADHD and a group of typically developing children. | Colombia | Differences were found between the case and control groups in the cognitive processes of memory, attention, and language, with lower scores in these areas for the case group compared to the controls. However, no significant differences were observed in the evaluation of executive functions. In the memory process, the case group demonstrated significantly lower average performance than the control group in auditory–verbal memory tasks, particularly in encoding and retrieval. Regarding attention, the case group exhibited lower average scores than the control group in auditory attention tasks, such as backward digit span, along with a higher number of errors and omissions. In terms of language, the case group performed worse than the control group in tasks assessing instruction-following and metalinguistic skills. | [13] |
Sample: Children aged 6 to 16 years diagnosed with ADHD. Objective: To compare the neurobiological functioning of children and adolescents with ASD and ADHD in the city of Manizales. | Colombia | In the comparison of the three subgroups—ADHD, Asperger’s, and control—the ADHD group demonstrated lower performance in visuo-constructional and memory tasks, particularly in spontaneous recall and cued recall tests. Regarding executive functions, the ADHD group obtained the lowest average scores in backward and forward digit span tasks, as well as in the number of categories completed. In terms of language performance, the ADHD group showed the lowest scores in verbal fluency and instruction-following tasks. | [36] |
Sample: Children aged 5 to 14 years with ADHD and 97 control subjects. Objective: To examine metalinguistic skills and reading processes in children diagnosed with ADHD, compared to a matched control group. | Colombia | Children diagnosed with ADHD demonstrated significantly lower performance than their neurotypical peers across all assessed metalinguistic and reading tasks, with the exception of spelling accuracy and silent reading comprehension, where no statistically significant differences were observed. | [20] |
Sample: Children aged 8 to 16 years with ADHD. Objective: To establish the relationship between two of the main cognitive deficits in ADHD (attention and inhibitory control), symptomatology (inattention and hyperactivity/impulsivity), and functional impact in patients diagnosed with ADHD without comorbid disorders. | Spain | The results indicated that greater deficits in cognitive functioning (attention and inhibitory control) predicted higher ADHD symptom severity (inattention and hyperactivity/impulsivity). Regarding the relationship between neuropsychological functioning and functional impact, the data suggested that greater attentional and inhibitory deficits predicted greater functional impairment, but only through the mediation of symptom severity. | [34] |
Sample: Children aged 6 to 14 years diagnosed with ADHD. Objective: To compare the neuropsychological performance characteristics of a sample of children with combined-type ADHD (ADHD-C), inattentive-type ADHD (ADHD-I), and a control group from the city of Manizales, Colombia. | Colombia | Differences were found in performance on visual attention tasks, with lower mean scores for the ADHD-C group compared to the ADHD-I group. Additionally, the ADHD-I group showed lower mean scores in metalinguistic skills (sound counting) compared to the control group. No significant differences were found in other measures included in the evaluation, such as intellectual capacity, memory, and executive functions. | [37] |
Sample: Children aged 10 to 14 years diagnosed with ADHD. Objective: To analyze the relationship between the neuropsychological profile and the level of emotional intelligence in fifth-grade children with suspected ADHD. | Dominican Republic | In the evaluation of the neuropsychological profile, the assessed group demonstrated a low-average performance in intellectual capacity measures. Additionally, cognitive measures derived from the DNI-Luria battery indicated low performance in tasks related to visual perception, spatial orientation, receptive speech, conceptual activity, immediate memory, logical memory, and attentional control. No association was found between intelligence quotient, neuropsychological profile, and emotional intelligence measures. | [38] |
Sample: Children aged 5 to 6 years, with and without ADHD. Objective: To compare the cognitive profile of preschool children at risk of dyslexia with the cognitive profile of children at risk of both dyslexia and coexisting ADHD. | Belgium | When comparing the group of children at risk for dyslexia with those at risk for both dyslexia and coexisting ADHD, no significant differences were found in most cognitive measures, except for executive functioning, where the dyslexia-only group performed better than the dyslexia–ADHD comorbidity group. The results indicated that the control group generally outperformed both risk groups across all evaluated measures, including phonological processing, executive functioning, receptive vocabulary, and processing speed, except for cognitive flexibility and delay of gratification. | [27] |
Sample: Children with ADHD aged 6 to 15 years and 24 control children aged 7 to 15 years. Objective: To describe the neuropsychological profile of patients with attention-deficit/hyperactivity disorder (ADHD) and its impact on executive functions and academic performance. | Spain | Children and adolescents with ADHD showed significantly lower scores than the neurotypical control group in all cognitive measures (motor functions, verbal abilities, abstract reasoning, linguistic, memory, attentional, and executive functions, as well as academic skills), except for perceptual abilities. More than half of the evaluated ADHD sample had a comorbid learning disorder. | [28] |
2. Materials and Methods
2.1. Type of Research
2.2. Sample
2.3. Procedure
2.4. Inclusion Criteria
- A minimum full-scale IQ score of 85, as measured by the abbreviated version of the Wechsler Intelligence Scale for Children (WISC-III), CX6 form (San Antonio, TX, USA) [41].
- For group classification, children in the ADHD group were required to have T-scores ≥ 65 on the inattention and hyperactivity/impulsivity dimensions of the Conners Rating Scales (NY, USA), as reported by both parents and teachers. In contrast, children in the control group were required to have T-scores ≤ 50 for the same dimensions [9].
- Provision of written informed consent by a parent or legal guardian, in accordance with institutional ethical standards.
2.5. Instruments
- Screening to Determine Inclusion and Exclusion Criteria.
- Conners’ Parent Rating Scale (CPRS) and Teacher Rating Scale (CTRS) [7]. Conners’ Rating Scale is a widely used behavioral assessment tool completed by parents and teachers to identify symptoms associated with ADHD. It is one of the most frequently employed instruments for evaluating behavioral difficulties in children within the Colombian context. The scale assesses a range of psychopathological domains commonly linked to ADHD, including hyperactivity, anxiety, depression, somatization, and behavioral and academic problems. A Spanish-language adaptation of the scale has been developed and validated, incorporating both factor analysis and normative data. For the present study, the version standardized for Colombian children was utilized to ensure cultural and contextual relevance.
- WISC III [42], abbreviated form C6 x2: Vocabulary and Block Design Subscales [41]. This abbreviated version employs the vocabulary and block design subtests. This is a standardized clinical instrument designed to assess intellectual functioning in children aged 6 to 16 years and 11 months. It is administered individually and provides composite scores for verbal IQ, performance IQ, and full-scale IQ, offering reliable estimates of a child’s overall intellectual ability.
- Semi-Structured Psychiatric Interview MINI-KID (Mini International Neuropsychiatric Interview for Children and Adolescents) [43]. This is a structured clinical diagnostic interview developed in accordance with DSM-IV and ICD-10 criteria. It is designed for individuals aged 6 to 17 years and 11 months and allows efficient administration, typically requiring approximately 25 min. Modeled after the adult version (MINI), the MINI-KID employs a branching logic based on key screening questions to determine the presence or absence of psychiatric disorders, thereby minimizing unnecessary items and administration time. The instrument assesses 23 psychiatric disorders, organized into modular sections, and includes a dedicated module for suicide risk assessment. Administration is preferably conducted in the presence of a parent or legal guardian, with items read verbatim to ensure standardization. Responses are binary (“yes” or “no”), and the progression through each module depends on initial screening responses. In the present study, the validated Spanish-language version of the MINI-KID was employed.
- Academic and Neuropsychological Performance [40]. The ENI battery is a standardized instrument designed to assess neuropsychological development in Spanish-speaking children aged 5 to 16 years. The neuropsychological components of the ENI evaluated a broad range of cognitive functions, including visual and auditory attention (e.g., picture cancellation, letter cancellation, digit span in progression and regression), verbal and visual memory (e.g., word list recall, free and cued recall, auditory–verbal recognition, complex figure copy and recall, and delayed recall), cognitive flexibility, and language abilities (e.g., instruction following). In addition, the protocol assessed metalinguistic skills (e.g., synthesis, spelling, phoneme counting, and word counting) as well as verbal fluency across both semantic and phonemic categories. Academic abilities were evaluated through ENI subtests that measure reading (accuracy, comprehension, and speed) and writing (narrative composition, accuracy, and speed). The use of this battery provided a comprehensive evaluation of the participants’ neuropsychological and academic profiles within a culturally and linguistically appropriate framework.
2.6. Data Analysis
3. Results
Description and Comparison Between the Experimental and Control Groups
4. Discussion
4.1. Sociodemographic Variables and ADHD
4.2. Intellectual Abilities and ADHD
4.3. Academic Performance and ADHD
4.4. Neuropsychological Performance and ADHD
5. Limitations and Future Research Directions
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Variable Group | Variable | Variable Abbrev. |
---|---|---|
Writing | Writing Accuracy: Syllable Dictation | WA: SD |
Writing Accuracy: Word Dictation | WA: WD | |
Writing Accuracy: Non-Word dictation | WA: NWD | |
Writing Accuracy: Sentence Dictation | WA: SD | |
Number of Words with Errors in Copying | NWE:C | |
Number of Words with Errors in Written Retrieval | NWE: WR | |
Narrative Composition Analysis: Narrative Coherence | NCA: NC | |
Narrative Composition Analysis: Written Retrieval Length | NCA: WRL | |
Copying Speed | CS | |
Written Retrieval Speed | WRS | |
Reading | Reading Accuracy: Syllables | RA: S |
Reading Accuracy: Words | RA:W | |
Reading Accuracy: Non-Words | RA: NW | |
Reading Accuracy: Sentence Reading | RA: SR | |
Number of Words with Errors in Oral Reading | NW: EO | |
Reading Comprehension: Sentence Reading | RC: SR | |
Reading Comprehension: Oral Reading | RC: OR | |
Reading Comprehension: Inferential Response in Oral reading (item 4) | RC: IROR4 | |
Reading Comprehension: Silent Reading of a Text | RC: SRT | |
Reading Speed | RS | |
Silent Reading Speed | SRS | |
Intelligence Quotient | Verbal Intellectual Quotient Measure—Vocabulary Task | VIQ-Voc |
Performance IQ Assessment—Block Design Task | PIQA-BD | |
Full-Scale IQ score | FS: IQS | |
Memory | Visual memory: copy score of the complex figure | VM: CSCF |
Visual memory: recall score of the complex figure. | VM: RSCF | |
Coding: Word List | C: WL | |
Coding/Word List/Working Memory—First Trial | CWL-WM- FT | |
Coding Spontaneous Recall | CDR | |
Coding Delayed Recall with Cues | CDRC | |
Verbal Auditory Recognition | VAR | |
Attention | Visual Attention—Drawing Cancellation Task | VA: DCT |
Omission of Drawings | OD | |
Commission of Drawings | CD | |
Visual Attention: Letter Cancellation Task | VA: LCT | |
Omissions: Letters | OL | |
Commissions: Letters | CL | |
Total Errors: Letters | TEL | |
Auditory Attention: Forward Digit Span Task | AA: FDS | |
Auditory Attention: Backward Digit Span Task | AA: BDS | |
Executive Functioning | Cognitive Flexibility: Number of Administered Trials | CF: NAT |
Cognitive Flexibility: Total Correct Responses | CF: TCR | |
Cognitive Flexibility: Total Errors | CF: TE | |
Cognitive Flexibility: Percentage of Errors | CF: PE | |
Cognitive Flexibility: Number of Categories | CF: NC | |
Cognitive Flexibility: Inability to Maintain Set | CF: IMS | |
Cognitive Flexibility: Number of Perseverative Responses | CF: NPR | |
Cognitive Flexibility: Percentage of Perseverative Responses | CF: PPR | |
Cognitive Flexibility: Number of Initial Conceptualization Trials | CF: NICT | |
Semantic Verbal Fluency (Animals) | SVF: A | |
Phonemic Verbal Fluency (Letter M) | PVF: M | |
Language | Instruction Following Task | IFT |
Metalinguistic skills: Synthesis task | MS: ST | |
Metalinguistic Skills: Sound Counting Task | MS: SC | |
Metalinguistic Skills: Spelling Task | MS: SPT | |
Metalinguistic Skills: Word Counting Task | MS: WCT |
Variable | Descriptive Statistics | Case | Control |
---|---|---|---|
Age | Mean | 9.41 | 9.43 |
Standard Deviation | 2.7 | 2.67 | |
Coefficient of Variation | 28.6% | 28.3% | |
Sex | Female % | 24.7 | 24.7 |
Male % | 75.3 | 7.53 | |
Socioeconomic status | Strata 1% | 19.6 | 19.6 |
Strata 2% | 67.0 | 67.0 | |
Strata 3% | 13.4 | 13.4 | |
Strata 6% | 1.0 | 1.0 | |
Education level | Preschool % | 5.2 | 3.1 |
First Grade% | 16.5 | 15.5 | |
Second Grade % | 14.4 | 12.4 | |
Third Grade % | 14.4 | 16.5 | |
Fourth Grade % | 6.2 | 9.3 | |
Fifth Grade % | 12.4 | 7.2 | |
Sixth Grade % | 11.3 | 12.4 | |
Seventh Grade % | 12.4 | 10.3 | |
Eight Grade % | 4.1 | 7.2 | |
Ninth Grade % | 3.1 | 5.2 | |
Tenth Grade % | 0.0 | 1.0 |
Variable | Case (Mean ± SD) | Control (Mean ± SD) | p-Value | Effect Size (d) (R-BC) |
---|---|---|---|---|
Writing | ||||
WA: SD | 6.134 ± 2.519 | 7.0208 ± 1.717 | 0.005 | 0.41140 (d) |
WA: WD | 3.969 ± 1.95 | 5.0833 ± 1.89 | <0.001 | 0.58033 (d) |
WA: NWD | 4.814 ± 2.078 | 5.5104 ± 1.536 | 0.036 | 0.16527 (R-BC) |
WA: SeD | 9.474 ± 5.803 | 11.5 ± 5.872 | 0.017 | 0.34710 (d) |
NWE: C | 9.329 ± 7.486 | 6.4719 ± 6.01 | 0.006 | 0.42098 (d) |
NWE: WR | 14.783 ± 10.001 | 12.4889 ± 7.581 | 0.284 | 0.09438 (R-BC) |
NCA: NC | 3.667 ± 1.616 | 4 ± 1.773 | 0.194 | 0.19653 (d) |
NCA: WRL | 70.56 ± 44.453 | 79.0652 ± 45.453 | 0.211 | 0.18920 (d) |
CS | 11.202 ± 6.182 | 12.4945 ± 6.72 | 0.187 | 0.20012 (d) |
WRS | 14.718 ± 9.154 | 13.5543 ± 7.425 | 0.360 | 0.13963 (d) |
Reading | ||||
RA: S | 6.505 ± 2.658 | 7.3542 ± 1.735 | 0.017 | 0.16323 (R-BC) |
RA: W | 9.526 ± 3.028 | 10.4271 ± 1.868 | 0.016 | 0.15174 (R-BC) |
RA: NW | 6.052 ± 2.252 | 6.8646 ± 1.626 | 0.003 | 0.23647 (R-BC) |
RA: SR | 7.758 ± 3.231 | 8.9583 ± 2.166 | 0.002 | 0.23673 (R-BC) |
NW: EO | 4.694 ± 4.952 | 2.4409 ± 3.002 | <0.001 | 0.38558 (R-BC) |
RC: SR | 6.295 ± 2.82 | 7.0313 ± 2.305 | 0.050 | 0.28593 (d) |
RC: OR | 4.539 ± 2.468 | 5.5789 ± 1.998 | 0.003 | 0.24802 (R-BC) |
RC: IROR4 | 1.056 ± 0.774 | 1.2935 ± 0.719 | 0.034 | 0.31761 (d) |
RC: SRT | 3.512 ± 2.034 | 4 ± 2.047 | 0.119 | 0.23936 (d) |
RS | 74.141 ± 42.451 | 92.2553 ± 46.433 | 0.007 | 0.40718 (d) |
SRS | 79.988 ± 49.172 | 97.0238 ± 50.899 | 0.030 | 0.34043 (d) |
Variable | Case (Mean ± SD) | Control (Mean ± SD) | p-Value | Effect Size (d) (R-BC) |
---|---|---|---|---|
Intelligence Quotient | ||||
VIQ: Voc | 25.24 ± 8.142 | 29.6354 ± 9.418 | <0.001 | 0.499 (d) |
PIQA-BD | 28.063 ± 14.633 | 32.1146 ± 14.294 | 0.054 | 0.280 (d) |
FS: IQS | 19.742 ± 4.391 | 23.0313 ± 5.387 | <0.001 | 0.34912 (R-BC) |
Memory | ||||
VM: CSCF | 7.835 ± 2.741 | 7.9063 ± 2.726 | 0.857 | 0.026 (d) |
VM: RSCF | 86.557 ± 34.62 | 90.875 ± 42.74 | 0.442 | 0.111 (d) |
C: WL | 26.155 ± 7.742 | 28.25 ± 7.182 | 0.032 | 0.178 (R-BC) |
CWL-WM- FT | 4.763 ± 1.841 | 5.5313 ± 1.515 | 0.002 | 0.455 (d) |
CSR | 7.237 ± 2.188 | 7.7708 ± 2.382 | 0.107 | 0.233 (d) |
CDRC | 7.278 ± 2.035 | 7.8333 ± 2.378 | 0.083 | 0.250 (d) |
VAR | 19.443 ± 3.416 | 19.7917 ± 4.203 | 0.528 | 0.090 (d) |
Attention | ||||
VA: DCT | 19.835 ± 9.077 | 20.3646 ± 9.874 | 0.699 | 0.055 (d) |
OD | 2.454 ± 4.1 | 2.7604 ± 5.761 | 0.671 | 0.061 (d) |
CD | 0.742 ± 1.856 | 0.5 ± 1.306 | 0.295 | 0.151 (d) |
VA: LCT | 22.804 ± 10.429 | 24.8854 ± 11.981 | 0.200 | 0.18531 (d) |
OL | 3.608 ± 7.927 | 1.5625 ± 2.854 | 0.003 | 0.23711 (R-BC) |
CL | 0.443 ± 0.968 | 0.3854 ± 1.268 | 0.722 | 0.05132 (d) |
TEL | 4.052 ± 7.97 | 1.9479 ± 3.014 | 0.003 | 0.23872 (R-BC) |
AA: FDS | 4.907 ± 1.001 | 5.0208 ± 1.248 | 0.487 | 0.10044 (d) |
AA-BDST | 3.206 ± 1.04 | 3.5521 ± 1.23 | 0.036 | 0.30366 (d) |
Executive Functioning | ||||
CF: NAT | 50.25 ± 6.383 | 50.1458 ± 6.066 | 0.908 | 0.01673 (d) |
CF: TCA | 33.667 ± 6.609 | 34.7604 ± 5.783 | 0.224 | 0.17613 (d) |
CF: TE | 16.412 ± 9.273 | 15.3854 ± 8.231 | 0.417 | 0.11713 (d) |
CF: PE | 31.708 ± 16.016 | 29.5313 ± 14.184 | 0.320 | 0.14392 (d) |
CF: NC | 1.927 ± 0.965 | 2.0625 ± 0.938 | 0.326 | 0.14228 (d) |
CF: IMS | 0.615 ± 0.8 | 0.6458 ± 0.821 | 0.790 | 0.03857 (d) |
CF: NPR | 12.063 ± 11.312 | 9.5625 ± 8.257 | 0.273 | 0.09147 (R-BC) |
CF: PPR | 22.969 ± 20.673 | 18.3958 ± 14.97 | 0.281 | 0.09006 (R-BC) |
CF: NICT | 16 ± 10.009 | 14.8438 ± 9.476 | 0.412 | 0.11863 (d) |
SVF: A | 14.216 ± 5.134 | 15 ± 5.07 | 0.287 | 0.15356 (d) |
PVF: M | 5.619 ± 3.67 | 6.2708 ± 3.782 | 0.226 | 0.17504 (d) |
Variable | Case (Mean ± SD) | Control (Mean ± SD) | p-Value | Effect Size (d) (R-BC) |
---|---|---|---|---|
Language | ||||
IFT | 8.546 ± 1.458 | 9.0521 ± 1.251 | 0.009 | 0.20758 (R-BC) |
MS: ST | 2.557 ± 2.194 | 3.2917 ± 2.161 | 0.020 | 0.33751 (d) |
MS: SC | 4.381 ± 2.687 | 5.3958 ± 2.306 | 0.008 | 0.21886 (R-BC) |
MS: SPT | 4.144 ± 2.332 | 4.8229 ± 1.908 | 0.081 | 0.14412 (R-BC) |
MS: WCT | 3.711 ± 2.872 | 4.8646 ± 2.382 | 0.006 | 0.22444 (R-BC) |
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Landínez-Martínez, D.; Montoya-Londoño, D.; Aguirre-Aldana, L.; Dussán-Lubert, C.; Robledo-Castro, C.; Partida-Gutierrez de Blume, A. Neuropsychological and Academic Performance in Colombian Children with Attention-Deficit Hyperactivity Disorder: A Comparative Study with a Control Group. Children 2025, 12, 561. https://doi.org/10.3390/children12050561
Landínez-Martínez D, Montoya-Londoño D, Aguirre-Aldana L, Dussán-Lubert C, Robledo-Castro C, Partida-Gutierrez de Blume A. Neuropsychological and Academic Performance in Colombian Children with Attention-Deficit Hyperactivity Disorder: A Comparative Study with a Control Group. Children. 2025; 12(5):561. https://doi.org/10.3390/children12050561
Chicago/Turabian StyleLandínez-Martínez, Daniel, Diana Montoya-Londoño, Lorena Aguirre-Aldana, Carmen Dussán-Lubert, Carolina Robledo-Castro, and Antonio Partida-Gutierrez de Blume. 2025. "Neuropsychological and Academic Performance in Colombian Children with Attention-Deficit Hyperactivity Disorder: A Comparative Study with a Control Group" Children 12, no. 5: 561. https://doi.org/10.3390/children12050561
APA StyleLandínez-Martínez, D., Montoya-Londoño, D., Aguirre-Aldana, L., Dussán-Lubert, C., Robledo-Castro, C., & Partida-Gutierrez de Blume, A. (2025). Neuropsychological and Academic Performance in Colombian Children with Attention-Deficit Hyperactivity Disorder: A Comparative Study with a Control Group. Children, 12(5), 561. https://doi.org/10.3390/children12050561