The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Design, Duration, Study Area, and Study Population
2.2. Sample Size Estimation, Sampling Procedures, and Selection Criteria
2.3. Data Collection, Sample Collection, and Laboratory Procedures
2.4. Laboratory Procedures
2.5. Data Management and Analysis
3. Results
3.1. Sociodemographic, Clinical, and Other Characteristics
3.2. The Seropositivity of Mumps IgG Antibodies and Associated Factors among School-Aged Children in Mbeya, Tanzania (N = 196)
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Sociodemographics Data | |||
---|---|---|---|
Variables/Characteristics | Frequency (n) | Percent (%) | |
Median [IQR] Age (yrs) | 13 (8–13) | ||
Median [IQR] Number of Siblings | 4 (2–8) | ||
Sex | Female | 124 | 63.3 |
Male | 72 | 36.7 | |
School | Mbarali | 96 | 48.9 |
Mkobwe | 33 | 16.8 | |
Ubaruku | 19 | 9.7 | |
Utyego | 48 | 24.5 | |
Father’s Education | None | 13 | 6.6 |
Primary | 60 | 30.6 | |
Secondary | 113 | 57.7 | |
Tertiary | 10 | 5.1 | |
Mother’s Education | None | 23 | 11.7 |
Primary | 94 | 47.9 | |
Secondary | 66 | 33.7 | |
Tertiary | 13 | 6.6 | |
Father’s Occupation | Farmer | 155 | 79.1 |
Business | 17 | 8.7 | |
Employed | 12 | 6.1 | |
Others | 12 | 6.1 | |
Mother’s Occupation | Farmer | 56 | 28.6 |
Business | 30 | 15.3 | |
Employed | 13 | 6.6 | |
Housewife | 42 | 21.4 | |
Tailor | 55 | 28.1 |
Variable/Characteristics | Frequency (n) | Percent (%) | |
---|---|---|---|
BMI Status | Normal (18–21 kg/m2) | 162 | 82.7 |
Underweight (13–<18 kg/m2) | 33 | 16.8 | |
Overweight (>21 kg/m2) | 1 | 0.51 | |
History of Mumps Vaccination | Yes | 0 | 0 |
No | 196 | 100 | |
History of Having Mumps Disease | No | 109 | 55.6 |
Yes | 87 | 44.4 | |
Palor | No | 193 | 98.5 |
Yes | 3 | 1.5 | |
Fatigue | No | 180 | 91.8 |
Yes | 16 | 8.2 | |
Headache | No | 175 | 89.3 |
Yes | 21 | 10.7 | |
Loss of Appetite | No | 184 | 93.9 |
Yes | 12 | 6.1 | |
Muscle Ache | No | 191 | 97.5 |
Yes | 5 | 2.5 | |
Fever | No | 103 | 52.5 |
Yes | 93 | 47.5 | |
Puffy Face | No | 148 | 75.5 |
Yes | 48 | 24.5 | |
Parotitis | No | 188 | 95.9 |
Yes | 8 | 4.1 | |
Previous Parotitis | No | 72 | 36.7 |
Yes | 124 | 63.3 | |
Painful Swallowing | No | 193 | 98.5 |
Yes | 3 | 1.50 | |
Sore Throat | No | 189 | 96.4 |
Yes | 7 | 3.6 | |
Sharing Utensils | No | 50 | 25.5 |
Yes | 146 | 74.5 |
Variable/Characteristics | Mumps Results | Logistic Regression | |||||
---|---|---|---|---|---|---|---|
Negative | Positive | Univariable | Multivariable | ||||
Frequency (%) | Frequency (%) | OR [95% CI] | p-Value | OR [95%CI] | p-Value | ||
Median [IQR] Age (yrs) | 13 (8–13) | 0.94 [0.58–1.55] | 0.822 | 0.66 [0.34–1.26] | 0.207 | ||
Median [IQR] Class | 7 (3–7) | 1.01 [0.57–1.78] | 0.969 | ||||
Median [IQR] Number of Siblings | 4 (2–8) | 1.89 [1.21–2.95] | 0.005 | 1.62 [0.92–2.85] | 0.096 | ||
Median [IQR] BMI (kg/m2) | 20.5 (14.3–25.1) | 0.97 [0.77–1.22] | 0.775 | ||||
Sex | Female (124) | 11(8.90) | 113 (91.10) | 1 | |||
Male (72) | 11 (15.30) | 61 (84.70) | 0.54 [0.22–1.32] | 0.175 | 0.28 [0.07–1.09] | 0.066 | |
BMI Status | Normal (162) | 17 (10.50) | 145 (89.50) | 1 | |||
Underweight (33) | 5 (15.20) | 28 (84.80) | 0.66 [0.22–1.93] | 0.443 | |||
Overweight (1) | 0 (0.00) | 1 (100.00) | – | ||||
School | Mbarali (96) | 8 (8.30) | 88 (91.70) | 1 | |||
Mkobwe (33) | 2 (6.10) | 31 (93.90) | 1.41 [0.28–7.00] | 0.675 | |||
Ubaruku (19) | 0 (0.00) | 19 (100.00) | – | ||||
Utyego (44) | 12 (27.30) | 32 (72.70) | 0.27 [0.10–0.72] | 0.009 | |||
Residence | Mbarali (54) | 8 (14.80) | 46 (85.20) | 1 | |||
Mkobwe (33) | 2 (6.10) | 31 (93.90) | 2.70 [0.54–13.55] | 0.229 | |||
Ubaruku (20) | 0 (0.00) | 20 (100.00) | – | ||||
Utyego (48) | 12 (25.00) | 36 (75.00) | 0.52 [0.19–1.41] | 0.200 | |||
Mpakani (41) | 0 (0.00) | 41 (100.00) | – | ||||
Mother’s Education | Tertiary (1) | 7 (53.80) | 6 (46.20) | 1 | |||
None (23) | 1 (4.30) | 22 (95.70) | 25.67 [2.62–251.30] | 0.005 | |||
Primary (94) | 7 (7.40) | 87 (92.60) | 14.5 [3.82–55.09] | 0.000 | |||
Secondary (66) | 7 (10.60) | 59 (89.40) | 9.83 [2.57–37.66] | 0.001 | 1.64 [0.93–2.92] | 0.090 | |
Mother’s Occupation | Farmer (55) | 5 (9.10) | 50 (90.90) | 1 | |||
Business (33) | 5 (16.70) | 25 (83.30) | 0.50 [0.13–1.89] | 0.307 | |||
Employed (10) | 6 (46.20) | 7 (53.80) | 0.12 [0.03–0.49] | 0.003 | |||
Housewife (42) | 3 (7.10) | 39 (92.90) | 1.30 [0.29–5.78] | 0.730 | |||
Tailor (56) | 3 (5.40) | 53 (94.60) | 1.77 [0.40–7.78] | 0.452 | 1.26 [0.95–1.68] | 0.113 | |
Muscle Ache | No (191) | 21 (11.00) | 170 (89.00) | 1 | |||
Yes (5) | 1 (20.00) | 4 (80.00) | 0.49 [0.05–4.63] | 0.537 | |||
Fever | No (103) | 20 (19.40) | 83 (80.60) | 1 | |||
Yes (93) | 2 (2.20) | 91 (97.80) | 10.96 [2.49–48.34] | 0.002 | 5.36 [1.02–28.22] | 0.044 | |
Previous Parotitis | No (72) | 16 (22.20) | 56 (77.80) | 1 | |||
Yes (124) | 6 (4.80) | 118 (95.20) | 5.62 [2.09–15.13] | 0.001 | 1.16 [0.28–4.47] | 0.835 | |
Sore Throat | No (189) | 21 (11.10) | 168 (88.90) | 1 | |||
Yes (7) | 1 (14.30) | 6 (85.70) | 0.75 [0.09–6.54] | 0.795 | |||
Sharing Utensils | No (50) | 16 (32.00) | 34 (68.00) | 1 | |||
Yes (146) | 6 (4.10) | 140 (95.90) | 10.98 [4.00–31.6] | 0.000 | 8.05 [1.99–32.65] | 0.003 |
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Mirambo, M.M.; Michael, F.; Nyawale, H.; Mbugano, F.; Walwa, M.B.; Mahamba, D.; Msanga, D.R.; Okamo, B.; Damiano, P.; Mshana, S.E. The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program. Children 2024, 11, 73. https://doi.org/10.3390/children11010073
Mirambo MM, Michael F, Nyawale H, Mbugano F, Walwa MB, Mahamba D, Msanga DR, Okamo B, Damiano P, Mshana SE. The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program. Children. 2024; 11(1):73. https://doi.org/10.3390/children11010073
Chicago/Turabian StyleMirambo, Mariam M., Fausta Michael, Helmut Nyawale, Frank Mbugano, Maneja B. Walwa, Dina Mahamba, Delfina R. Msanga, Bernard Okamo, Prisca Damiano, and Stephen E. Mshana. 2024. "The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program" Children 11, no. 1: 73. https://doi.org/10.3390/children11010073
APA StyleMirambo, M. M., Michael, F., Nyawale, H., Mbugano, F., Walwa, M. B., Mahamba, D., Msanga, D. R., Okamo, B., Damiano, P., & Mshana, S. E. (2024). The High Seropositivity of Mumps Virus IgG Antibodies among School-Aged Children in Rural Areas of the Mbarali District in the Mbeya Region, Tanzania: It Is High Time for Consideration in the National Immunization Program. Children, 11(1), 73. https://doi.org/10.3390/children11010073