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Biomedicines 2018, 6(1), 18; https://doi.org/10.3390/biomedicines6010018

Photodynamic Therapy Activated by Intense Pulsed Light in the Treatment of Nonmelanoma Skin Cancer

1
Italian Association Outpatient Dermatologists, 00177 Rome, Italy
2
Skin Center, Dermo-Aesthetic Lasers Centers, 67051 Avezzano, Italy
*
Author to whom correspondence should be addressed.
Received: 5 November 2017 / Revised: 18 December 2017 / Accepted: 29 January 2018 / Published: 7 February 2018
(This article belongs to the Special Issue Photodynamic Therapy in Cancer)
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Abstract

Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) or methyl aminolevulinate (MAL) has proven to be a highly effective conservative method for the treatment of actinic keratosis (AK), Bowen’s disease (BD), and superficial basal cell carcinoma (sBCC). PDT is traditionally performed in association with broad-spectrum continuous-wave light sources, such as red or blue light. Recently, intense pulsed light (IPL) devices have been investigated as an alternative light source for PDT in the treatment of nonmelanoma skin cancers (NMSC). We herein report our observational findings in a cohort of patients with a diagnosis of AK, sBCC, and BD that is treated with MAL-PDT using IPL, as well as we review published data on the use of IPL-PDT in NMSC. View Full-Text
Keywords: photodynamic therapy; nonmelanoma skin cancer; MAL; intense pulsed light device photodynamic therapy; nonmelanoma skin cancer; MAL; intense pulsed light device
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Piccolo, D.; Kostaki, D. Photodynamic Therapy Activated by Intense Pulsed Light in the Treatment of Nonmelanoma Skin Cancer. Biomedicines 2018, 6, 18.

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