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Chemosensors
Volume 11
Issue 5
10.3390/chemosensors11050280
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Review

Fluorescent Probes for Biomacromolecules Based on Monomethine Cyanine Dyes

by
Pavel G. Pronkin
and
Alexander S. Tatikolov
*
N.M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 119334 Moscow, Russia
*
Author to whom correspondence should be addressed.
Chemosensors 2023, 11(5), 280; https://doi.org/10.3390/chemosensors11050280
Submission received: 3 April 2023 / Revised: 24 April 2023 / Accepted: 5 May 2023 / Published: 7 May 2023
(This article belongs to the Special Issue Application of Luminescent Materials for Sensing)
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Abstract

Monomethine cyanine dyes (MCDs) are widely applied as biomolecular probes and stains in biochemical and biomedical research. This is based on the ability of MCDs to associate with biomolecules (mostly nucleic acids) with significant fluorescent growth. The present review considers the works devoted to the properties of MCDs and the influence of noncovalent interactions with biomacromolecules on their properties, as well as their use as noncovalent probes and stains for various biomacromolecules. The synthesis and photonics (photophysics and photochemistry; in particular, the generation of the triplet state) of MCDs are also considered. Areas and prospects of the practical applications of MCDs in biochemistry and biomedicine are discussed.
Keywords: monomethine cyanine dyes; nucleic acids; proteins; fluorescent probes; spectral-fluorescent properties; aggregates; noncovalent interactions; photonics monomethine cyanine dyes; nucleic acids; proteins; fluorescent probes; spectral-fluorescent properties; aggregates; noncovalent interactions; photonics
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MDPI and ACS Style

Pronkin, P.G.; Tatikolov, A.S. Fluorescent Probes for Biomacromolecules Based on Monomethine Cyanine Dyes. Chemosensors 2023, 11, 280. https://doi.org/10.3390/chemosensors11050280

AMA Style

Pronkin PG, Tatikolov AS. Fluorescent Probes for Biomacromolecules Based on Monomethine Cyanine Dyes. Chemosensors. 2023; 11(5):280. https://doi.org/10.3390/chemosensors11050280

Chicago/Turabian Style

Pronkin, Pavel G., and Alexander S. Tatikolov. 2023. "Fluorescent Probes for Biomacromolecules Based on Monomethine Cyanine Dyes" Chemosensors 11, no. 5: 280. https://doi.org/10.3390/chemosensors11050280

APA Style

Pronkin, P. G., & Tatikolov, A. S. (2023). Fluorescent Probes for Biomacromolecules Based on Monomethine Cyanine Dyes. Chemosensors, 11(5), 280. https://doi.org/10.3390/chemosensors11050280

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