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Methoxyflurane in Non-Life-Threatening Traumatic Pain—A Retrospective Observational Study

A.C.E. Genève Ambulances SA, 1225 Geneva, Switzerland
Paramedic School, 1231 Geneva, Switzerland
Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, 1211 Geneva, Switzerland
Emergency Department, Guy’s and St. Thomas’ NHS Foundation Trust, London SE1 9RS, UK
Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada
School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON K1G 5Z3, Canada
Ottawa Hospital Research Institute, Ottawa, ON K1Y 4E9, Canada
Author to whom correspondence should be addressed.
Academic Editor: Tim Kilner
Healthcare 2021, 9(10), 1360;
Received: 24 August 2021 / Revised: 6 October 2021 / Accepted: 12 October 2021 / Published: 13 October 2021
(This article belongs to the Special Issue Urgent and Acute Prehospital Care)
Pain management is a key issue in prehospital trauma. In Switzerland, paramedics have a large panel of analgesic options. Methoxyflurane was recently introduced into Switzerland, and the goal of this study was to describe both the effect of this medication and the satisfaction of its use. This was a retrospective cohort study, performed in one emergency ambulance service. It included adult patients with traumatic pain and a self-assessment of 3 or more on the visual analogue scale or verbal numerical rating scale. The primary outcome was the reduction in pain between the start of the care and the arrival at the hospital. Secondary outcomes included successful analgesia and staff satisfaction. From December 2018 to 4 June to October 2020, 263 patients were included in the study. Most patients had a low prehospital severity score. The median pain at arrival on site was 8 and the overall decrease in pain observed was 4.2 (95% CI 3.9–4.5). Regarding secondary outcomes, almost 60% had a successful analgesia, and over 70% of paramedics felt satisfied. This study shows a reduction in pain, following methoxyflurane, similar to outcomes in other countries, as well as the attainment of a satisfactory level of pain reduction, according to paramedics, with the advantage of including patients in their own care. View Full-Text
Keywords: analgesia; prehospital; traumatic; methoxyflurane; pain analgesia; prehospital; traumatic; methoxyflurane; pain
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MDPI and ACS Style

Ozainne, F.; Cottet, P.; Lojo Rial, C.; von Düring, S.; Fehlmann, C.A. Methoxyflurane in Non-Life-Threatening Traumatic Pain—A Retrospective Observational Study. Healthcare 2021, 9, 1360.

AMA Style

Ozainne F, Cottet P, Lojo Rial C, von Düring S, Fehlmann CA. Methoxyflurane in Non-Life-Threatening Traumatic Pain—A Retrospective Observational Study. Healthcare. 2021; 9(10):1360.

Chicago/Turabian Style

Ozainne, Florian, Philippe Cottet, Carlos Lojo Rial, Stephan von Düring, and Christophe A. Fehlmann. 2021. "Methoxyflurane in Non-Life-Threatening Traumatic Pain—A Retrospective Observational Study" Healthcare 9, no. 10: 1360.

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