Tai Chi as a Mind–Body Intervention to Address Chronic Pain in Socially Isolated Older Adults: A Narrative Review
Abstract
1. Introduction
2. Methods
2.1. Study Design
2.2. Search Strategy
2.3. Eligibility Criteria
2.4. Study Selection and Review Process
2.5. Narrative Synthesis Approach
2.6. Methodological Considerations
3. Results
3.1. Loneliness, Social Isolation, and Chronic Pain
3.2. Tai Chi and Chronic Pain Outcomes
3.3. Tai Chi and Social Outcomes
3.4. Combined Effects of Tai Chi on Pain and Social Outcomes
3.5. Physiological Mechanisms
4. Discussion
4.1. Which Form of Tai Chi Is Best, and for Whom?
4.2. Addressing Co-Morbid Conditions for Persons Living with Chronic Pain
4.3. Controlling the Cost of Chronic Pain
5. Limitations
6. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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| Author (Year) | Country | Study Design | Sample Size (N) | Age (Mean/Range) | % Female | Population Notes |
|---|---|---|---|---|---|---|
| Bloomberg et al. (2025) [10] | United Kingdom | Longitudinal | 7336 | ≥50 | 54.60% | Predominantly White |
| Brown et al. (2026) [20] | United States | Cross-sectional | 82 | Mean 50.5 | 68.30% | Native American sample |
| Camacho et al. (2024) [9] | United States | Cross-sectional | 2706 | ≥50 | NR | Racially diverse sample |
| Chan et al. (2017) [16] | China | Pilot study | 48 | ≥60 | NR | Community-based |
| Chen et al. (2025) [21] | Japan | Non-randomized controlled trial | 84 | ≥60 | 59.50% | Exercise intervention |
| Dagnino & Campos (2022) [22] | Not specified | Narrative review | N/A | Older adults | N/A | Pain management review |
| Gillsjö et al. (2021) [23] | Sweden | Qualitative | 20 | 72–79 | 70.00% | Interviews |
| Han et al. (2025) [8] | China | Cohort (CHARLS) | 3109 | ≥60 | NR | National longitudinal dataset |
| Hong et al. (2024) [24] | United States | Prospective longitudinal | 13,365 | Mean 69 | NR | Large aging cohort |
| Hosseini et al. (2025) [25] | Iran | Cross-sectional | 1675 | Mean 69.7 | 45.40% | Community-dwelling |
| Koren et al. (2021) [26] | Not specified | Systematic review | 10 studies | ≥60 | N/A | Mixed methods |
| Kotwal et al. (2021) [1] | United States | Cross-sectional | 5976 | ≥50 | 50.40% | End-of-life population |
| Lee et al. (2020) [27] | United States | Qualitative | 18 | ≥65 | 61.10% | Tai Chi intervention |
| Lim et al. (2024) [28] | Not specified | Systematic review and meta-analysis | 22 RCTs | Pre-frail older adults | N/A | Exercise interventions |
| Maité et al. (2025) [29] | Belgium | Prospective (2-wave) | 332 | ≥50 | 81.60% | Chronic pain population |
| Matsuda et al. (2025) [30] | Japan | Prospective cohort | 4709 | Mean 73.8 | 56.40% | Community-dwelling |
| Noguchi et al. (2023) [11] | Japan | Cross-sectional | 21,463 | ≥65 | 51.60% | Large population study |
| Straus et al. (2022) [31] | United States | Cross-sectional | 4069 | Mean 62 | 9.80% | U.S. veterans |
| Tang et al. (2019) [32] | Not specified | Systematic review | 10 studies | ≥65 | N/A | Non-pharmacologic interventions |
| Weber et al. (2020) [33] | Not specified | Systematic review and meta-analysis | 37 RCTs (3224 participants) | ≥60 | N/A | Tai Chi/Qigong |
| Wong et al. (2024) [34] | China | Mixed methods | 4153 | Mean 75.3 | 82.70% | Community-based |
| Yang et al. (2024) [35] | China | Cross-sectional | 1087 | ≥60 | 49.60% | Mind–body exercise |
| You et al. (2023) [17] | United States | Narrative review | N/A | Older adults | N/A | Tai Chi and pain |
| You et al. (2020) [36] | United States | Exploratory | 40 | Mean 74 | 42.50% | Biomarker study |
| Zheng et al. (2017) [37] | China | Qualitative | 20 | Mean 62 | 70.00% | High-risk stroke population |
| Author (Year) | Study Focus | Key Variables | Main Findings |
|---|---|---|---|
| Bloomberg et al. (2025) [10] | Pain and loneliness trajectory | Loneliness, depression, chronic pain | Loneliness increased before and after pain onset; depression rose sharply at onset and then stabilized |
| Brown et al. (2026) [20] | Social support and pain | Emotional support, instrumental support, pain intensity/interference | Social isolation associated with higher pain interference; instrumental support buffered pain effects |
| Camacho et al. (2024) [9] | Loneliness and pain | Loneliness, pain presence | Greater loneliness associated with higher likelihood of reporting pain |
| Chan et al. (2017) [16] | Tai Chi and social outcomes | Tai Chi/Qigong, loneliness, social support | Tai Chi participants reported reduced loneliness and improved social support |
| Chen et al. (2025) [21] | Tai Chi intervention | Tai Chi vs. resistance exercise, pain | Tai Chi significantly improved subjective pain following 12-week intervention |
| Dagnino & Campos (2022) [22] | Pain management strategies | Chronic pain, non-pharmacologic therapies | Tai Chi identified as effective non-pharmacologic modality for pain management |
| Gillsjö et al. (2021) [23] | Pain and social experience | Chronic pain, loneliness, social isolation | Pain experiences reinforced by loneliness, stigma, and lack of validation |
| Han et al. (2025) [8] | Pain and social factors | Chronic pain, loneliness, social isolation | Loneliness and isolation associated with increased chronic pain over time |
| Hong et al. (2024) [24] | Health and loneliness | Self-rated health, anxiety, purpose, pain | Poor physical and psychological health predicted greater loneliness |
| Hosseini et al. (2025) [25] | Pain and comorbidities | Chronic pain, sleep, depression, cognition, isolation | Chronic pain associated with poor sleep, depression, cognitive impairment, and living alone |
| Koren et al. (2021) [26] | Tai Chi and social support | Tai Chi, social isolation, social support | Majority of Tai Chi interventions improved perceived social support |
| Kotwal et al. (2021) [1] | Epidemiology of isolation | Social isolation, loneliness | High prevalence of isolation and loneliness; associated with socioeconomic and functional factors |
| Lee et al. (2020) [27] | Tai Chi and pain (qualitative) | Tai Chi, chronic low back pain | Mixed pain outcomes; improved motivation, relaxation, and social support |
| Lim et al. (2024) [28] | Exercise and frailty | Multimodal exercise, Tai Chi, frailty | Exercise improved frailty status; frequency predicted functional gains |
| Maité et al. (2025) [29] | Pain and stigma | Chronic pain, stigma, social isolation | Pain associated with stigma, mental distress, and increased isolation |
| Matsuda et al. (2025) [30] | Pain, isolation and disability | Chronic pain, social participation | Pain and isolation jointly increased risk of disability |
| Noguchi et al. (2023) [11] | Loneliness and back pain | Loneliness, social isolation, low back pain | Loneliness associated with back pain; combined isolation and loneliness had synergistic effect |
| Straus et al. (2022) [31] | Loneliness and comorbidity | Loneliness, chronic pain, mental health | Loneliness strongly associated with chronic pain and psychiatric comorbidities |
| Tang et al. (2019) [32] | Non-pharmacologic pain care | Tai Chi, Qigong, acupuncture, guided imagery | Mind–body interventions effective in reducing pain in older adults |
| Weber et al. (2020) [33] | Tai Chi and QoL | Tai Chi/Qigong, QoL, depression, sleep | Tai Chi improved QoL, reduced depression, improved sleep and social engagement |
| Wong et al. (2024) [34] | Mental health and treatment response | Anxiety, loneliness, cognition, pain | Loneliness and psychological factors predicted poorer treatment response |
| Yang et al. (2024) [35] | Mind–body exercise and QoL | Tai Chi, social support, resilience | Social support and resilience mediated relationship between exercise and QoL |
| You et al. (2023) [17] | Tai Chi and pain | Tai Chi, multisite pain | Tai Chi reduced pain and improved physical and cognitive function |
| You et al. (2020) [36] | Mechanisms of Tai Chi | Tai Chi, beta-endorphins, inflammation | Tai Chi reduced beta-endorphins, suggesting enhanced endogenous pain modulation |
| Zheng et al. (2017) [37] | Tai Chi (qualitative outcomes) | Tai Chi, pain, sleep, relationships | Participants reported improved pain, sleep, emotional well-being, and social relationships |
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Russin, N.H.; Martin, M.P. Tai Chi as a Mind–Body Intervention to Address Chronic Pain in Socially Isolated Older Adults: A Narrative Review. Healthcare 2026, 14, 1464. https://doi.org/10.3390/healthcare14111464
Russin NH, Martin MP. Tai Chi as a Mind–Body Intervention to Address Chronic Pain in Socially Isolated Older Adults: A Narrative Review. Healthcare. 2026; 14(11):1464. https://doi.org/10.3390/healthcare14111464
Chicago/Turabian StyleRussin, Nina H., and Matthew P. Martin. 2026. "Tai Chi as a Mind–Body Intervention to Address Chronic Pain in Socially Isolated Older Adults: A Narrative Review" Healthcare 14, no. 11: 1464. https://doi.org/10.3390/healthcare14111464
APA StyleRussin, N. H., & Martin, M. P. (2026). Tai Chi as a Mind–Body Intervention to Address Chronic Pain in Socially Isolated Older Adults: A Narrative Review. Healthcare, 14(11), 1464. https://doi.org/10.3390/healthcare14111464

