Abstract
In the 1920s, the English philosopher W.E. Johnson introduced a characterization of the symmetric Dirichlet prior distribution in terms of its predictive distribution. This is typically referred to as Johnson’s “sufficientness” postulate, and it has been the subject of many contributions in Bayesian statistics, leading to predictive characterization for infinite-dimensional generalizations of the Dirichlet distribution, i.e., species-sampling models. In this paper, we review “sufficientness” postulates for species-sampling models, and then investigate analogous predictive characterizations for the more general feature-sampling models. In particular, we present a “sufficientness” postulate for a class of feature-sampling models referred to as Scaled Processes (SPs), and then discuss analogous characterizations in the general setup of feature-sampling models.
1. Introduction
Exchangeability (de Finetti [1]) provides a natural modeling assumption in a large variety of statistical problems, and it amounts to the assumption that the order in which observations are recorded is not relevant. Consider a sequence of random variables defined on a common probability space and taking values in an arbitrary space, which is assumed to be Polish. The sequence is exchangeable if and only if
for any permutation of the set and any . By virtue of the celebrated de Finetti representation theorem, exchangeability of is tantamount to asserting the existence of a random element , defined on a (parameter) space , such that, conditionally on , the s are independent and identically distributed with common distribution , i.e.,
where is the distribution of . In a Bayesian setting, takes on the interpretation of a prior distribution for the parameter object of interest. In this sense, the de Finetti representation theorem is a natural framework for Bayesian statistics. For mathematical convenience, is assumed to be a Polish space, equipped with the Borel -algebra . Hereafter, with the term parameter, we refer to both a finite- and an infinite-dimensional object.
Within the framework of exchangeability (1), a critical role is played by the predictive distributions, namely, the conditional distributions of the th observation given . The problem of characterizing prior distributions in terms of their predictive distributions has a long history in Bayesian statistics, starting from the seminal work of the English philosopher Johnson [2] who provided a predictive characterization of the symmetric Dirichlet prior distribution. Such a characterization is typically referred to as Johnson’s “sufficientness” postulate. Species-sampling models (Pitman [3]) provide arguably the most popular infinite-dimensional generalization of the Dirichlet distribution. They form a broad class of nonparametric prior models that correspond to the assumption that in (1) is an almost surely discrete random probability measure
where: (i) are non-negative random weights almost surely summing up to 1; (ii) are random species’ labels, independent of , and i.i.d. with common (non-atomic) distribution P. The term species refers to the fact that the law of is a prior distribution for the unknown species composition of a population of individuals s, with belonging to a species with probability for . In the context of species-sampling models, Regazzini [4] and Lo [5] provided a “sufficientness” postulate for the Dirichlet process (Ferguson [6]). Such a characterization was then extended by Zabell [7] to the Pitman–Yor process (Perman et al. [8], Pitman and Yor [9]) and by Bacallado et al. [10] to the more general Gibbs-type prior models (Gnedin and Pitman [11]).
In this paper, we introduce and discuss Johnson’s “sufficientness” postulates in the feature-sampling setting, which generalizes the species-sampling setting by allowing each individual of the population to belong to multiple species, now called features. We point out that feature-sampling models are extremely important in different areas of application; see, e.g., Griffiths and Ghahramani [12], Ayed et al. [13] and the references therein. Under the framework of exchangeability (1), the feature-sampling setting assumes that
and
where: (i) conditionally on , are independent Bernoulli random variables with parameters ; (ii) are -valued random weights; (iii) are random features’ labels, independent of , and i.i.d. with common (non-atomic) distribution P. That is, individual displays feature if and only if , which happens with probability . For example, if, conditionally on , displays only two features, say and , it equals the random measure . The distribution is the law of a Bernoulli process with parameter , which is denoted by , whereas the law of is a nonparametric prior distribution for the unknown feature probabilities , i.e., a feature-sampling model. Here, we investigate the problem of characterizing prior distributions for in terms of their predictive distributions, with the goal of providing “sufficientness” postulates for feature-sampling models. We discuss such a problem and present partial results for a class of feature-sampling models referred to as Scaled Process (SP) priors for (James et al. [14], Camerlenghi et al. [15]). With these results, we aim at stimulating future research in this field to obtain “sufficientness” postulates for general feature-sampling models.
The paper is structured as follows. In Section 2, we present a brief review on Johnson’s “sufficientness” postulates for species-sampling models. Section 3 focuses on nonparametric prior models for the Bernoulli process, i.e., feature-sampling models; we review their definitions, properties, and sampling structures. In Section 4, we present a “sufficientness” postulate for SPs. Section 5 concludes the paper by discussing our results and conjecturing analogous results for more general classes of feature-sampling models.
2. Species-Sampling Models
To introduce species-sampling models, we assume that the observations are -valued random elements, and is supposed to be a Polish space whose Borel -algebra is denoted by . Thus, contains all the possible species’ labels of the populations. When we deal with species-sampling models, the hierarchical formulation (1) specializes as
where is an almost surely discrete random probability measure on , and denotes its law. We also remind the reader that: (i) are non-negative random weights almost surely summing up to 1; (ii) are random species’ labels, independent of , and i.i.d. as a common (non-atomic) distribution P. Using the terminology of Pitman [3], the discrete random probability measure is a species-sampling model. In Bayesian nonparametrics, popular examples of species-sampling models are: the Dirichlet process (Ferguson [6]), the Pitman–Yor process (Perman et al. [8], Pitman and Yor [9]), and the normalized generalized Gamma process (Brix [16], Lijoi et al. [17]). These are examples belonging to a peculiar subclass of species-sampling models, which are referred to as Gibbs-type prior models (Gnedin and Pitman [11], De Blasi et al. [18]). More general subclasses of species-sampling models are, e.g., the homogeneous normalized random measures (Regazzini et al. [19]) and the Poisson–Kingman models (Pitman [20], Pitman [21]). We refer to Lijoi and Prünster [22] and Ghosal and van der Vaart [23] for a detailed and stimulating account on species-sampling models and their use in Bayesian nonparametrics.
Because of the almost sure discreteness of in (4), a random sample from features ties, that is, if . Thus, induces a random partition of the set into blocks, labeled by , with corresponding frequencies , such that and . From Pitman [3], the predictive distribution of is of the form
for any , having set , with g and being arbitrary non-negative functions that satisfy the constraint . The predictive distribution (5) admits the following interpretation: (i) corresponds to the probability that is a new species, that is, a species not observed in ; (ii) corresponds to the probability that is a species in . The functions g and completely determine the distribution of the exchangeable sequence and, in turn, the distribution of the random partition of induced by . Predictive distributions of popular species-sampling models, e.g., the Dirichlet process, the Pitman–Yor process, and the normalized generalized Gamma process, are of the form (5) for suitable specification of the functions g and . We refer to Pitman [21] for a detailed account of random partitions induced by species-sampling models and generalizations thereof.
Here, we recall the predictive distribution of Gibbs-type prior models (Gnedin and Pitman [11], De Blasi et al. [18]). Let us first introduce the definition of these processes.
Definition 1.
Let and let P be a (non-atomic) distribution on . A Gibbs-type prior model is a species-sampling model with a predictive distribution of the form
for any , where is a collection of non-negative weights that satisfy the recurrence relation for all , , with the proviso .
Note that the Dirichlet process is a Gibbs-type prior model that corresponds to
for , where we have denoted by the Pochhammer symbol for the rising factorials. Moreover, the Pitman–Yor process is a Gibbs-type prior model corresponding to
for and . We refer to Pitman [20] for other examples of Gibbs-type prior models and for a detailed account of the s; see also Pitman [21] and the references therein.
Because of de Finetti’s representation theorem, there exists a one-to-one correspondence between the functions g and in the predictive distribution (5) and the law of , i.e., the de Finetti measure. This is at the basis of Johnson’s “sufficientness” postulates, characterizing species-sampling models through their predictive distributions. Regazzini [4] and, later, Lo [5] provided the first “sufficientness” postulate for species-sampling models, showing that the Dirichlet process is the unique species-sampling model for which the function g depends on only through n, and the function depends on only through n and for . Such a result was extended in Zabell [24], providing the following “sufficientness” postulate for the Pitman–Yor process: The Pitman–Yor process is the unique species-sampling model for which the function g depends on only through n and k, and the function depends on only through n and for . Bacallado et al. [10] discussed the “sufficientness” postulate in the more general setting of Gibbs-type prior models, showing that Gibbs-type prior models are the sole species-sampling models for which the function g depends on only through n and k, and the function depends on only through n, k, and . This result shows a critical difference—at the sampling level—between the Pitman–Yor process and Gibbs-type prior models, which lies in the inclusion of the sampling information on the observed number of distinct species in the probability of observing, at the -th draw, a species already observed in the sample.
3. Feature-Sampling Models
Feature-sampling models generalize species-sampling models by allowing each individual to belong to more than one species, which are now called features. To introduce feature-sampling models, we consider a space of features , which is assumed to be a Polish space, and we denote by its Borel -field. Thus, contains all the possible features’ labels of the population. Observations are represented through the counting measure (3), whose parameter is an almost surely discrete measure with masses in . When we deal with feature-sampling models, the hierarchical formulation (1) specializes as
where is an almost surely discrete random measure on , and denotes its law. We also remind the reader that: (i) conditionally on , are independent Bernoulli random variables with parameters ; (ii) are -valued random weights; (iii) are random features’ labels, independent of , and i.i.d. with common (non-atomic) distribution P. Completely random measures (CRMs) (Daley and Vere-Jones [25], Kingman [26]) provide a popular class of nonparametric priors , the most common examples of which are the Beta process prior and the stable Beta process prior (Teh and Gorur [27], James [28]); see also Broderick et al. [29] and the references therein for other examples of CRM priors and generalizations thereof. Recently, Camerlenghi et al. [15] investigated an alternative class of nonparametric priors , generalizing CRM priors and referring to these as Scaled Processes (SPs). SP priors first appeared in the work of James [28].
We assume a random sample to be modeled as in (7), and we introduce the predictive distribution of , that is, the conditional probability of given . Note that, because of the pure discreteness of , the observations may share a random number of distinct features, say , denoted here as , and each feature is displayed exactly by of the n individuals as . Since the features’ labels are immaterial and i.i.d. form the base measure P, the conditional distribution of , given , may be equivalently characterized through the vector , where: (i) is the number of new features displayed by the th individual, namely, hitherto unobserved out of the sample ; (ii) is a -valued random variable for any , and if the th individual displays feature ; it equals 0 otherwise. Hence, the predictive distribution of is
where we denote by f a probability distribution evaluated at , and where and is the sampling information. In the rest of this section, we specify the function f under the assumption of a CRM prior and an SP prior, showing its dependence on , and . In particular, we show how SP priors allow one to enrich the predictive distribution of CRM priors by including additional sampling information in terms of the number of distinct features and their corresponding frequencies.
3.1. Priors Based on CRMs
Let denote the space of all bounded and finite measures on , that is to say, iff for any bounded set . Here, we recall the definition of a Completely Random Measure (CRM) (see, e.g., Daley and Vere-Jones [25]).
Definition 2.
A Completely Random Measure (CRM) on is a random element taking values in the space such that the random variables are independent for any choice of bounded and disjoint sets and for any .
We remind the reader that Kingman [26] proved that a CRM may be decomposed as the sum of a deterministic drift and a purely atomic component. In Bayesian nonparametrics, it is common to consider purely atomic CRMs without fixed points of discontinuity, that is to say, may be represented as , where is a sequence of random atoms and are the random locations. An appealing property of purely atomic CRMs is the availability of their Laplace functional; indeed, for any measurable function , one has
where is a measure on called the Lévy intensity of the CRM , and it is such that
for any bounded Borel set A. Here, we focus on homogeneous CRMs by assuming that the atoms s and the locations s are independent; in this case, the Lévy measure may be written as
for some measurable function and a probability measure P on , called the base measure, which is assumed to be diffuse. In this case, the distribution of will be denoted as , and the second integrability condition in (10) reduces to the following:
In the feature-sampling framework, may be used as a prior distribution if the sequence of atoms is in between , which happens if the Lévy intensity has support on . A noteworthy example, widely used in this setting, is the stable Beta process prior (Teh and Gorur [27]). It is defined as a CRM with Lévy intensity
where , , and (James [28], Masoero et al. [30]). Now, we describe the predictive distribution for an arbitrary CRM . For the sake of clarity, we fix the following notation:
to denote the probability mass functions of a Poisson with parameter and a Bernoulli random variable with parameter , respectively. We refer to James [28] for a detailed posterior analysis of CRM priors; see also Broderick et al. [29] and the references therein.
Theorem 1
(James [28]). Let be exchangeable random variables modeled as in (7), where equals . If is a random sample that displays distinct features , and feature appears exactly times in the samples, such as , then
being
Proof.
We consider James [28] (Proposition 3.2) for Bernoulli product models (see also Camerlenghi et al. [15] (Proposition 1)); thus, the distribution of , given , equals the distribution of
where such that , and are Bernoulli random variables with parameters , respectively, such that each is a random variable whose distribution is with a density function of the form
By exploiting the previous predictive characterization, we can derive the posterior distribution of given by means of a direct application of the Laplace functional. Indeed, the distribution of equals . Thus, for any , we have the following:
where we used the representation and the fact that the s are independent Bernoulli random variables conditionally on . We now use the Laplace functional for to get
As a direct consequence, the posterior distribution of given is a Poisson distribution with mean . Again, by exploiting the predictive representation (14), the posterior distribution of , as , is a Bernoulli with the following mean:
□
Corollary 1.
Let be exchangeable random variables modeled as in (7), where is the law of the stable Beta process. If is a random sample that displays distinct features , and feature appears exactly times in the samples, such as , then
where denotes the Pochhammer symbol for .
Proof.
It is sufficient to specialize Theorem 1 for the stable Beta process. In particular, from Theorem 1, the posterior distribution of given is a Poisson distribution with mean
Moreover, the parameters of the Bernoulli random variables are equal to
as . □
3.2. SP Priors
From Theorem 1, under CRM priors, the distribution of the number of new features is a Poisson distribution that depends on the sampling information only through the sample size n. Moreover, the probability of observing a feature already observed in the sample, say , depends only on the sample size n and the frequency of feature out of the initial sample. Camerlenghi et al. [15] showed that SP priors allow one to enrich the predictive structure of CRM priors, including additional sampling information in the probability of discovering new features. To introduce SP priors, consider a CRM on , where are positive random atoms and are i.i.d. random atoms, with Lévy intensity satisfying
Consider the ordered jumps of the CRM and define the random measure
normalizing by the largest jump. The definition of SPs follows with a suitable change in the measure of (James et al. [14], Camerlenghi et al. [15]). Let us denote by a regular version of the conditional probability distribution of given . Now denote by a positive random variable with density function on and define
The distribution of is obtained by mixing with respect to the density function . Thus, we are ready to define an SP.
Definition 3.
A Scaled Process (SP) prior on is defined as the almost surely discrete random measure
where has distribution and is a sequence of independent random variables with common distribution P, also independent of . We will write .
A thoughtful account with a complete posterior analysis for SPs is given in Camerlenghi et al. [15]. Here, we characterize the predictive distribution (8) of SPs.
Theorem 2.
(Camerlenghi et al. [15], James [28]). Let be exchangeable random variables modeled as in (7), where equals . If is a random sample that displays distinct features , and feature appears exactly times in the samples, such as , then the conditional distribution of , given , has posterior density:
Moreover, conditionally on and ,
being
Proof.
The representation of the predictive distribution (19) follows from Camerlenghi et al. [15] (Proposition 2). Indeed, the posterior distribution of the largest jump directly follows from [15] (Equation (4)). In addition, the authors of [15] (Proposition 2) showed that the conditional distribution of , given and , equals the distribution of the following counting measure:
where and is a CRM with Lévy intensity of the form
Moreover, are Bernoulli random variables with parameters , respectively, such that conditionally on , each has a distribution with a density function of the form
As in the proof of Theorem 1, we show that the distribution of equals . Thus, by the evaluation of the Laplace functional, one may easily realize that the last random sum has a Poisson distribution with mean . Moreover, by exploiting the posterior representation (20), the variables , such as , conditionally on and , are independent and Bernoulli distributed with mean
□
Remark 1.
According to (18), the conditional distribution of given may include the whole sampling information, depending on the specification of ν and , and hence, the conditional distribution of given may also include such sampling information. As a corollary of Theorem 2, the conditional distribution of given is a mixture of Poisson distributions that may include the whole sampling information; in particular, the amount of sampling information in the posterior distribution is uniquely determined by the mixing distribution, namely by the conditional distribution of , given .
Hereafter, we specialize Theorem 2 for the stable SP, that is, a peculiar SP defined through a CRM with a Lévy intensity such that for a parameter . We refer to Camerlenghi et al. [15] for a detailed posterior analysis of the stable SP prior.
Corollary 2.
Let be exchangeable random variables modeled as in (7), where equals , with for some . If is a random sample that displays distinct features , and feature appears exactly times in the samples, such as , then the conditional distribution of , given , has posterior density:
having denoted by the classical Euler Beta function. Moreover, conditionally on and ,
Proof.
The proof is a plain application of Theorem 2 under the choice . □
4. Predictive Characterizations for SPs
In this section, we introduce and discuss Johnson’s “sufficientness” postulates in the context of feature-sampling models under the class of SP priors. According to Theorem 1, if the feature-sampling model is a CRM prior, then the conditional distribution of , given , is a Poisson distribution that depends on the sampling information only through the sample size n. Moreover, the conditional probability of generating an old feature given depends on the sampling information only through n and . As shown in Theorem 2, SP priors enrich the predictive structure of CRM priors through the conditional distribution of the latent variable given the observable sample . In the next theorem, we characterize the class of SP priors for which the conditional distribution of given depends on the sampling information only through n.
Theorem 3.
Let be exchangeable random variables modeled as in (7), where equals and . Moreover, suppose that is a random sample that displays distinct features , and feature appears exactly times in the samples, such as . If is a continuous function on the compact support with , and the function is continuous on its domain, then the conditional distribution of the latent variable given depends on the sampling information only through n if and only if on for some constant .
Proof.
First of all, if is defined on the compact support and if on for some constant , then it is easy to see that the posterior distribution of in (18) depends only on n and not on the other sample statistics. We now show the reverse implication. The posterior density of , conditionally on , satisfies (18), and it is proportional to
where . Then, there exists such that it holds that
Because of the assumptions imposed, the distribution of does not depend on , nor on the corresponding sample frequencies . Accordingly, the function
depends only on a and n, but not on k and . Then, putting together (23) and (24), it holds that
where c is the normalizing factor, and it does not depend on the variable a. By choosing , thanks to Equation (25), we can state that the following function:
which is defined for any and does not depend on a, but only on k and n. Since the previous assertion is true for any , one may select , thus obtaining the following identity:
for some constant , independent of a, but that may depend on n. Substituting (27) into (26), we obtain that
is a function that does not depend on a, but only on n and k. As a consequence, we have that
for a suitable constant , which does not depend on . To conclude, we take a derivative of the previous expression with respect to a, and this allows us to show that
namely, for , where C is a positive constant. This is a Lévy intensity; indeed, it satisfies the condition (11). Outside the interval , may be defined arbitrarily; indeed, the values of on do not affect the posterior distribution of (18). □
Remark 2.
Note that in Theorem 3, we have supposed that has a compact support on ; thus, we are interested in defining λ on ; outside the interval, λ can be defined arbitrarily because it does not affect the posterior distribution (18) of . From the proof of Theorem 3, it becomes apparent that if the support of is the entire positive real line , the posterior distribution of the largest jump depends only on n if and only if on for some constant . However, in this case, λ does not meet the integrability condition (11); hence, this can only considered a limiting case. It is interesting to observe that such a limiting situation, with the additional assumption , corresponds to the Beta process case with and (Griffiths and Ghahramani [12]).
Now, we characterize SPs for which the posterior distribution of depends only on n and , but not on the sample frequencies of the different features . Here, we assume that has full support a priori. The following characterization has been provided in Camerlenghi et al. [15] (Theorem 3), but for completeness, we report the proof.
Theorem 4.
(Camerlenghi et al. [15]). Let be exchangeable random variables modeled as in (7), where equals and . Suppose that is a random sample that displays distinct features , and feature appears exactly times in the sample, such as . If is a strictly positive function on and continuously differentiable, and λ is continuously differentiable, then the conditional distribution of the latent variable , given , depends on only through n and if and only if on for some constant and .
Proof.
By arguing as in the proof of Theorem 3, the posterior density of given is proportional to
where . Then, there exists such that it holds that
As a consequence,
If the density function does not depend on , then the following function
depends only on and a, but not on the frequency counts. Therefore, (29) boils down to
where the function on the right-hand side of (30) is independent of a for any choice of the vector of sampling information . Now, since the vector can be chosen arbitrarily, we can make the choice , such that the function
does not depend on , where . Moreover, suppose that ; thus,
does not depend on , which implies that
for a constant with respect to a, which can only depend on k and n. By substituting (33) into (31), we obtain
which is independent of . Now, it is possible to choose in the previous function. Therefore, there exists a constant independent of a such that the following identity holds:
By taking the derivative of the previous equation two times with respect to a, one obtains
which is an ordinary differential equation in that can be solved by separation of variables. In particular, we obtain
We recall from Theorem 2 that the conditional distribution of given uniquely determines the amount of sampling information included in the conditional distribution of the number of new features given . Such sampling information may range from the whole information, in terms of n, , and , to the sole information on the sample size n. According to Theorem 4, the stable SP prior of Corollary 2 is the sole SP prior for which the conditional distribution of the number of new features given depends on the sampling information only on n and . Moreover, according to Theorem 3, the Beta process prior is the sole SP prior for which the conditional distribution of the number of new features given depends on the sampling information only on n. In particular, Theorems 3 and 4 show that the Beta process prior and the stable SP prior may be considered, to some extent, the feature sampling counterparts of the Dirichlet process prior the Pitman–Yor process prior.
5. Discussion and Conclusions
In this paper, we have introduced and discussed Johnson’s “sufficientness” postulates in the context of feature-sampling models. “Sufficientness” postulates have been investigated extensively in the context of species-sampling models, providing an effective classification of species-sampling models on the basis of the form of their corresponding predictive distributions. Here, we made a first step towards the problem of providing an analogous classification for feature-sampling models. In particular, we obtained Johnson’s “sufficientness” postulates when the class of feature-sampling models is restricted to the class of scaled process priors. However, the results presented in the paper remain preliminary, and do not at all provide a complete answer to the characterization problem within the general class of feature-sampling models. This problem remains open.
Within the feature-sampling setting, the predictive distribution is of the form (8), though for the purpose of providing “sufficientness” postulates, one may focus on feature-sampling models exhibiting a general predictive distribution of the following type:
Note that (35) is a probability distribution, and it must satisfy a consistency condition, as usual. Among all the feature-sampling models whose predictive distribution can be written in the form (35), we are interested in characterizing nonparametric priors such that: (i) The function g depends on the sampling information only through n, and the function depends only on ; (ii) g depends only on and depends only on ; (iii) g depends only on and depends only on . In our view, these characterizations may provide a complete picture of sufficientness postulates within the feature setting, and they are also fundamental to guiding the selection of the prior distribution. We conjecture that CRMs are the nonparametric priors satisfying the characterization (i), the SP with a stable Lévy measure is an example of prior satisfying (ii), and no examples satisfying (iii) have been considered in the current literature. Results in this direction are in Battiston et al. [31], where the authors characterize an exchangeable feature allocation probability function (Broderick et al. [32]) in product forms; this could be a stimulating point of departure to study the characterization problem depicted above.
Author Contributions
Writing–original draft, F.C. and S.F.; writing–review and editing, F.C. and S.F. The authors contributed equally to this work. All authors have read and agreed to the published version of the manuscript.
Funding
This research received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program under grant agreement No. 817257.
Institutional Review Board Statement
Not applicable.
Informed Consent Statement
Not applicable.
Data Availability Statement
Not applicable.
Acknowledgments
F.C. is extremely grateful to Eugenio Regazzini for the time spent at the Department of Mathematics of University of Pavia during his Ph.D. studies in Mathematical Statistics; F.C. wants to especially thank Eugenio Regazzini for having introduced him to the study of Bayesian Statistics with a stimulating Ph.D. course held together with Antonio Lijoi. S.F. wishes to express his gratitude to Eugenio Regazzini, whose fundamental contributions to Bayesian statistics have always been a great source of inspiration, transmitting enthusiasm and methods for the development of his own research. The authors gratefully acknowledge the financial support from the Italian Ministry of Education, University, and Research (MIUR), “Dipartimenti di Eccellenza” grant 2018-2022. F.C. is a member of the Gruppo Nazionale per l’Analisi Matematica, la Probabilità e le loro Applicazioni (GNAMPA) of the Istituto Nazionale di Alta Matematica (INdAM).
Conflicts of Interest
The authors declare no conflict of interest.
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