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Article

SAFIRE: Mathematical Analysis of a Differentiable Fuzzy-Inspired Rule-Scoring Surrogate for Medical Tabular Classification

1
Institute of Information Technology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam
2
Faculty of Mathematics, Thai Nguyen University of Education, Thai Nguyen 250000, Vietnam
3
Faculty of Electronics Engineering, Thai Nguyen University of Technology, Thai Nguyen 250000, Vietnam
*
Author to whom correspondence should be addressed.
Mathematics 2026, 14(13), 2255; https://doi.org/10.3390/math14132255 (registering DOI)
Submission received: 21 May 2026 / Revised: 12 June 2026 / Accepted: 18 June 2026 / Published: 24 June 2026
(This article belongs to the Special Issue Advances in Fuzzy Logic and Artificial Neural Networks, 2nd Edition)

Abstract

We develop SAFIRE (Self-Attention Fuzzy-Inspired Rule Estimator), a differentiable fuzzy-inspired rule-scoring surrogate for binary medical tabular classification coupling multi-head self-attention, Gaussian membership functions, and Hard Concrete gates for continuous rule scoring. We position SAFIRE as a smooth surrogate of the discrete L0-regularised rule-selection problem and establish five mathematical results and one complexity remark: (1) the relaxed objective is differentiable almost everywhere under positive Gaussian widths (enforced by a Softplus reparameterisation) and fixed batch-normalisation statistics; (2) the deterministic-inference active threshold is strictly stricter than the expected-nonzero training threshold, identifying Hard Concrete gates as continuous rule-scoring devices rather than automatic pruning mechanisms; (3) per-sample forward complexity identifies attention and rule layers as the dominant terms; (4) the Softplus–BatchNorm–linear rule operator violates all four triangular-norm axioms—with necessary and sufficient conditions per axiom and a no-finite-parameterisation impossibility result—while a Softplus reparameterisation restores coordinate-wise monotonicity; (5) a margin-based upper bound characterises disagreement between the full classifier and a top-k rule-only surrogate; and (6) the Softplus-reparameterised constrained variant is provably coordinate-wise monotone with explicit asymptotic regimes. Evaluated on four University of California, Irvine (UCI), medical binary tabular benchmarks under repeated stratified cross-validation, SAFIRE-Prog is statistically competitive with strong interpretable, modern, and gradient-boosting baselines, with one Bonferroni-significant gain over RuleFit on the Diabetic Retinopathy Debrecen corpus. The 48-configuration Hard Concrete sweep, constrained-variant comparison, and a top-k fidelity analysis (per-fold range 0.73–0.95) provide quantitative companion measurements for the mathematical framework. A supplementary large-scale hospital electronic health record (EHR) benchmark (Diabetes 130-US Hospitals, n=101,766) shows the rule-scoring mechanism scales to ∼105 records and, under severe class imbalance, statistically matches gradient boosting on accuracy while significantly exceeding it on macro-F1. The results offer a mathematically auditable pathway towards interpretable, auditable rule scoring for medical tabular classification, with rule signatures defined in a projected latent space rather than over raw clinical variables.
Keywords: neuro-fuzzy systems; triangular norms; Hard Concrete distribution; L0 regularization; differentiable rule scoring; multi-head attention; latent rule signatures; mathematical analysis of machine learning; medical tabular classification neuro-fuzzy systems; triangular norms; Hard Concrete distribution; L0 regularization; differentiable rule scoring; multi-head attention; latent rule signatures; mathematical analysis of machine learning; medical tabular classification

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MDPI and ACS Style

Nguyen, P.-N.; Nguyen, T.-H.; Nguyen, T.-N.; Tran, M.-D.; Nguyen, T.-T.; Nguyen, T.-L. SAFIRE: Mathematical Analysis of a Differentiable Fuzzy-Inspired Rule-Scoring Surrogate for Medical Tabular Classification. Mathematics 2026, 14, 2255. https://doi.org/10.3390/math14132255

AMA Style

Nguyen P-N, Nguyen T-H, Nguyen T-N, Tran M-D, Nguyen T-T, Nguyen T-L. SAFIRE: Mathematical Analysis of a Differentiable Fuzzy-Inspired Rule-Scoring Surrogate for Medical Tabular Classification. Mathematics. 2026; 14(13):2255. https://doi.org/10.3390/math14132255

Chicago/Turabian Style

Nguyen, Phuong-Nhung, Thu-Hien Nguyen, Thu-Nga Nguyen, Manh-Dong Tran, Truong-Thang Nguyen, and Tuan-Linh Nguyen. 2026. "SAFIRE: Mathematical Analysis of a Differentiable Fuzzy-Inspired Rule-Scoring Surrogate for Medical Tabular Classification" Mathematics 14, no. 13: 2255. https://doi.org/10.3390/math14132255

APA Style

Nguyen, P.-N., Nguyen, T.-H., Nguyen, T.-N., Tran, M.-D., Nguyen, T.-T., & Nguyen, T.-L. (2026). SAFIRE: Mathematical Analysis of a Differentiable Fuzzy-Inspired Rule-Scoring Surrogate for Medical Tabular Classification. Mathematics, 14(13), 2255. https://doi.org/10.3390/math14132255

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