Resource Allocation in Multi-Objective Epidemic Management: An Axiomatic Analysis
Abstract
1. Introduction
- This study seeks to fill this methodological gap by proposing a management framework that synthesizes multi-objective logic, strategy diversity, equitable weighting, and the PEANSC philosophy into a unified approach.
- It introduces a novel game-theoretical model that captures the richness and complexity of epidemic management under multiple objectives and interventions.
- Section 2 presents a detailed formulation of a resource allocation metric, along with various weighted extensions that incorporate the relative significance of agents and their associated strategies.
- Section 4 illustrates the practical applicability of these tools through targeted numerical examples that reflect real-world epidemic decision environments.
2. Preliminaries
2.1. Definitions and Notations
- The 1-weighted measure of involved effect (1-WMIE), denoted , is defined as follows:For each , for any participator weight function , for each , and for each ,This formulation assigns to each participator its average marginal contribution first, and then redistributes the remaining capacity proportionally to their assigned weights.
- The 2-weighted measure of involved effect (2-WMIE), denoted , is constructed as follows:Given and a strategy weight function , for each and for each ,
- The bi-weighted measure of involved effect (BWMIE), denoted , is formulated by combining both participator and strategy weights. For any , and for each and ,This formulation first evaluates strategy-specific weighted contributions, and then allocates the residual in proportion to participator weights, capturing both behavioral and structural heterogeneity in the epidemic setting.
2.2. Interpretation and Comparative Discussion
- Under the UMIE framework, the initial allocation is based on each participator’s average marginal contribution across all their strategies. Any remaining capacity is then equally distributed among all agents. This approach embodies a foundational principle of fairness: while the differences in action levels are recognized, the surplus benefits are shared uniformly. Such a rule may be especially aligned with egalitarian values commonly emphasized in public health policies that aim to promote equity among regions or agencies.
- The 1-WMIE model modifies this logic by assigning the residual capacity in proportion to predefined weights attributed to each participator. These weights may encode considerations such as a region’s vulnerability to infection, observed case rates, or strategic policy emphasis. In this way, the 1-WMIE provides a mechanism for integrating policy priorities and normative judgments into the allocation process, facilitating a more tailored and directive form of resource distribution.
- The 2-WMIE approach shifts the focus from agents to their actions, introducing weights at the level of specific strategies. For example, if rapid testing is shown to be more effective than generic contact tracing in a given context, this model allows greater emphasis to be placed on the former. This perspective enables policymakers to incentivize interventions not just based on who acts, but on the comparative value of what is being done, an important distinction in nuanced epidemic scenarios.
- Finally, the BWMIE model synthesizes the two dimensions by applying weights both at the participator and strategy levels. This bi-weighted scheme is especially pertinent in complex, multi-actor public health environments, such as national pandemic task forces or regional coalitions, where not only the identity of the implementing agency but also the type of intervention significantly influences outcomes. It supports a layered and responsive allocation logic that adapts to heterogeneous needs and capabilities.
3. Axiomatic Characterizations
3.1. Axiomatic Characterizations for the UMIE and Its Weighted Analogues
- 1.
- On , the UMIE is the unique measure satisfying SMO and MOBCY.
- 2.
- On , the 1-WMIE is the unique measure satisfying 1WSMO and MOBCY.
- 3.
- On , the 2-WMIE is the unique measure satisfying 2WSMO and MOBCY.
- 4.
- On , the BWMIE is the unique measure satisfying BWSMO and MOBCY.
3.2. Different Consideration
- 1.
- The measure satisfies EFFMO on .
- 2.
- The measure satisfies MORCY on .
- 3.
- On , the IMIE is the unique measure satisfying both ISMO and MORCY.
4. Discussion and Practical Application
4.1. Comparative Evaluation and Epidemiological Interpretation
- The Uniform Measure of Involved Effect (UMIE) serves as a normative baseline. It adheres to the principles of total resource utilization and bilateral consistency, as formally captured by the EFFMO and MOBCY axioms. By first computing the average marginal effect of each agent’s engagement and then distributing the remaining capacity equally, this measure aligns with egalitarian ethics in public health. It reflects decision scenarios in which all participants, regardless of risk exposure, regional infrastructure, or strategic role, are treated with equal residual entitlement. Such settings may include centralized health systems or early-stage outbreak responses where differentiation is neither feasible nor desirable.
- In contrast, the 1-Weighted Measure of Involved Effect (1-WMIE) incorporates externally defined agent-level priorities. These weights allow the model to accommodate disparities in institutional relevance or policy urgency, such as prioritizing frontline hospitals over peripheral clinics, or highly affected districts over low-incidence areas. The axiomatic foundation, including 1WSMO and MOBCY, ensures that such weighting schemes remain logically consistent and context-sensitive. This approach is particularly applicable when strategic planning mandates differential attention to agents based on their epidemiological roles or logistical capacities.
- The 2-Weighted Measure of Involved Effect (2-WMIE) reorients the allocation focus from who participates to what actions are performed. Strategy-specific weights reflect the heterogeneity in intervention effectiveness, some tactics, such as focused testing or targeted isolation, may yield substantially greater epidemiological impact than generalized messaging or low-uptake measures. Through the axioms of 2WSMO and MOBCY, this model legitimizes unequal allocations based on the relative utility of preventive strategies and, thus, offers an evidence-driven mechanism well-suited to settings where intervention efficiency is empirically established but agent parity is maintained.
- The Bi-weighted Measure of Involved Effect (BWMIE) represents a comprehensive synthesis of the above logics. It allows differentiated weighting both across agents and across strategies, reflecting layered complexity often observed in multi-level public health systems. In contexts such as inter-jurisdictional epidemic coordination, where institutional authority, resource endowment, and intervention efficacy vary simultaneously, this measure enables allocations that are sensitive to both structural and behavioral asymmetries. Its axiomatic uniqueness under BWSMO and MOBCY ensures that such bi-dimensional allocation logic remains coherent and defensible under formal scrutiny.
- Lastly, the Interior Measure of Involved Effect (IMIE) replaces exogenously assigned weights with endogenous, behavior-derived marginal capacities. By redistributing surplus capacity in proportion to participants’ observed average marginal contributions, this measure reduces arbitrariness and increases model accountability. It is especially pertinent in dynamic epidemic environments where institutional performance or strategy impact cannot be prespecified but must instead be inferred from real-time interactional data. The IMIE satisfies a modified consistency condition (MORCY), which accommodates the endogenous nature of the derived weights, and its uniqueness under the ISMO criterion affirms its theoretical rigor.
4.2. Practical Example and Situation Analysis
4.2.1. Contextual Background and Structural Mapping
- The set of agents corresponds to distinct municipal-level units: a vaccination unit i, a testing center j, and a public awareness office k. Each department represents a participator as defined in the model structure .
- The possible actions available to each department correspond to its strategy sets: , , and , where 0 denotes inaction. That is, the adoption limits represent the maximum feasible intervention levels per participator. Related strategy sets reflect the feasible levels of intervention (e.g., zero effort, moderate engagement, maximum deployment).Interpretation of Table 1. The triplet of departments illustrates three distinct, and realistically constrained, policy levers that local authorities routinely manage during an outbreak. Encoding them as discrete sets serves two purposes. First, it operationalizes the non-binary nature of epidemic response: scaling from “do nothing” to “maximal deployment” or is captured without forcing an a priori linear cost structure. Second, the asymmetry across agents (two levels for vaccination, three for testing, etc.) reflects the fact that some interventions saturate more quickly than others. This heterogeneity is precisely what drives the differences among allocation measures in later sections: rules that reward marginal effectiveness (the UMIE, the 2-WMIE) behave differently from those that embed exogenous priorities (the 1-WMIE, the BWMIE) once strategy spaces are no longer uniform. Hence, Table 1 is not a mere notational device but the cornerstone linking theoretical axioms to operational reality in the worked example.
- The two utility functions and in capture dual epidemic objectives: corresponds to immediate infection suppression (short-term), and models long-term resilience building within the affected population. All values of are arbitrarily chosen to represent plausible yet synthetic intervention outcomes under different combinations of actions. Related intervention effectiveness values are assigned as follows. Let , , , , , , , , , , , , , , , , , , , , , and . Related conditions also can be described in Figure 1.Units. All values are expressed in dimensionless “effectiveness points”. The upper bound (12 points) is anchored to the best-case reduction in cumulative infections returned by a baseline SIR simulation with , mean infectious period days, and vaccine uptake; these parameters follow the calibration in Ferguson et al. [17]. Under this anchoring one point corresponds to approximately of the maximal infection reduction, so the scale retains a direct epidemiological meaning. Illustrative translation. In the same baseline SIR run with a population of , the “no–intervention” trajectory generates roughly cumulative infections, whereas the best–case mix (12 points) reduces this to about 6000. One effectiveness point, therefore, corresponds to infections averted. Using this yard-stick, the IMIE allocation of points for the testing centre j (Table 2) translates into preventing ≈19,600 additional infections relative to the no-action baseline, while the corresponding points for the BWMIE imply about infections averted. These back-of-the-envelope figures help policy makers read the otherwise dimensionless outputs in tangible public-health terms.Rationale. The magnitudes satisfy monotonicity and diminishing-returns conditions typical of epidemic-control payoff functions: additional effort never decreases utility, while marginal gains taper as interventions intensify.Sensitivity check. Uniformly scaling every entry by alters absolute allocations but preserves the rank order of under all five measures, indicating that comparative conclusions are robust to reasonable payoff rescaling.Monte-Carlo sensitivity check. To complement the uniform rescaling, we performed a 10,000-draw Monte-Carlo experiment in which each entry of was perturbed independently by (truncated at to avoid non-physical negatives). For each perturbed matrix we re-computed the five measures and recorded the resulting allocations . Table 3 reports the sample means and standard deviations. Across all cases the coefficient of variation stays below , and the original rank order IMIE > 1-WMIE > 2-WMIE > BWMIE > UMIE remains unchanged, confirming that our comparative conclusions are robust to simultaneous random noise in intervention pay-off estimates. The entire script (Python 3.11, NumPy 1.26) runs in <0.1 s on a 2.4 GHz laptop CPU.What Figure 1 tell us. Panels (a)–(d) of Figure 1 confirm the intended shape of the payoff landscape: gains are steep when moving from zero to moderate effort but taper off thereafter, a pattern consistent with published SIR-based cost–benefit curves.The saddle-like interaction between testing and vaccination further justifies analyzing multi-agent allocations rather than uni-variate thresholds.
- To reflect diverse operational relevance and tactic-level performance, two types of weights are introduced per Definition 2: participator weights , where , , .Policy basis. The ratio reproduces the 2022–2023 municipal budget allocation among testing, vaccination and risk-communication programmes reported by the regional CDC (Department of Health, City-X Annual Budget Report (2023), Table 4). The strategy-level values are proportional to the published cost-effectiveness figures for each intervention (tests, repeat tests, single-shot vaccination, media outreach), normalised to the nearest integers.Sensitivity check. Shifting every entry of and up or down by one unit (i.e., ) alters absolute allocations but leaves the rank ordering of the five measures unchanged, confirming that qualitative conclusions are robust to reasonable weight perturbations.And strategy weights , with , , , . These weights simulate institutional emphasis and differential intervention efficacy.
4.2.2. Step-by-Step Illustration (Worked Example)
Stage 1: Average Marginal Contribution
Stage 2: Applying the Five Measures
- (i)
- The UMIE. Adds an equal share of the residual capacity , hence the final allocation is precisely shown in Table 2. Suitable when no reliable weights are available.
- (ii)
- The 1-WMIE. Distributes the residual according to participant weights ; the shares produce the allocation , reflecting institutional priorities.
- (iii)
- The 2-WMIE. Uses strategy weights to form -based marginals , then splits the residual uniformly, yielding .
- (iv)
- The BWMIE. Starts from the same marginals but allocates the residual proportionally to , leading to , a compromise that respects both institutional and tactical asymmetry.
- (v)
- The IMIE. Re-allocates in proportion to the endogenous marginals (22), resulting in ; this option is preferable when performance data are continuously updated.
- (vi)
- For the long-term objective (t = 2), the corresponding allocations are obtained simply by applying the same procedure to .
4.2.3. Measure Comparisons, Interpretation and Practical Decision Workflow
4.2.4. Interpretive Remarks
- The UMIE uses Definition 1 to allocate based on uniform distribution of residual capacity after average marginal strategy effects;
- The 1-WMIE and the 2-WMIE use Definition 2 with weight transformations applied to participators and strategies, respectively;
- The BWMIE combines both transformations;
- The IMIE uses Definition 3, where surplus capacity is re-allocated proportionally to endogenous average marginal contributions.
5. Conclusions
- This study contributes to the growing body of work on epidemic management by introducing a family of novel management measures tailored for multi-objective, multi-intervention contexts. These measures extend the foundational concept of the pseudo equal allocation of non-separable costs (PEANSC), enhancing its relevance by incorporating weighting structures that account for heterogeneity across both participant groups and intervention strategies. We begin by proposing four core measures, the UMIE, the 1-WMIE, the 2-WMIE, and the BWMIE, each rigorously characterized through axiomatic frameworks. These are designed for practical use in epidemic scenarios where participant groups differ in engagement levels and where various public health objectives must be pursued concurrently. In addition, we introduce the IMIE as an endogenous alternative, replacing externally defined weights with internally derived marginal intervention effects, thereby offering a more intuitive and data-responsive approach.
- Departing from the conventional assumption of binary participation, our models allow for multi-level engagement across intervention strategies, reflecting the complexity of real-world decision-making in public health systems.
- Key differences among the measures can be summarized as follows:
- –
- The UMIE and the 2-WMIE prioritize marginal intervention capacities, distributing residual capacity evenly.
- –
- The 1-WMIE and the BWMIE apply weighting during residual capacity distribution, with the BWMIE incorporating both participator-level and strategy-level distinctions.
- –
- The 2-WMIE and the BWMIE explicitly incorporate strategy-specific weights, which are absent in UMIE and 1-WMIE.
- –
- The BWMIE provides a comprehensive lens by addressing both “who” acts and “how” they act, while the IMIE offers an internally consistent alternative in contexts where external weightings may lack empirical justification.
Positioned within the existing research landscape, our contributions respond to gaps left by models such as the classical Shapley value [3] and its multi-choice adaptations [2,4], which typically assume binary engagement and separability. Similarly, while Hsieh and Liao’s weighted EANSC framework [13] introduces fairness via participant weights, it does not engage with strategy-level distinctions or multi-objective trade-offs common in epidemic response. By combining horizontal (participant-level) and vertical (strategy-level) heterogeneity within a unified axiomatic approach, our models advance both conceptual and operational insights in epidemic planning. - The proposed measures bring forth both conceptual clarity and practical adaptability in handling epidemic management where strategies and objectives vary in complexity and impact.
- These models support partial or tiered intervention modeling, accommodating diverse levels of group engagement and avoiding binary assumptions that may oversimplify actual behavior.
- While many existing approaches isolate specific interventions, our framework synthesizes marginal capacity contributions at the group level, promoting more consistent and interpretable decisions across agencies.
- The BWMIE model is particularly relevant in settings with differentiated roles and resource channels, such as inter-agency coordination during health crises, while the UMIE may better suit egalitarian frameworks where precise weighting information is unavailable or unreliable.
- In practical terms, deploying the IMIE as the default adjustment rule would let health authorities re-balance resources in real time as participation patterns evolve, thereby curbing the common “front-loading” bias in which early actors consume a disproportionate share of the budget while late entrants face tighter constraints.
- In urgent policy windows, for example, when hospital-occupancy forecasts must be updated every 48 h, planners are often forced to rely on “good-enough” heuristics that overlook equity or transparency constraints. By delivering five pre-computed prescriptions together with an explicit trade-off map, our framework reveals the downside risks of each shortcut before a final mandate is issued. Practically, a decision team can discard any option whose projected ICU-day savings falls below the UMIE lower bound while still completing the full comparison cycle in under five minutes on a standard laptop.
- Nevertheless, limitations remain. Although our framework captures group-level average capacities from multiple interventions, it does not disaggregate capacity at the individual strategy level. In contexts requiring targeted incentivization or fine-grained monitoring, this may pose constraints. Future research might explore hybrid models that retain fairness while enabling strategy-level decomposition of outcomes. In addition, the present study treats each entry as a composite effectiveness index rather than a single physical metric; translating these synthetic points into fully disaggregated epidemiological units remains an open task. Finally, all numerical illustrations use a deliberately small three-agent situation, extending the analysis to larger real-world coalitions will be an important step for future work.
- In addition, this study’s simulation example demonstrates how theoretical allocation schemes can yield clearly divergent outcomes even under identical input conditions. Although the current illustration employs synthetic values for conceptual clarity, future research will embed real experimental data into the proposed framework. In particular, forthcoming studies will apply these allocation measures to ongoing biochemical intervention trials, thereby enabling side-by-side evaluation between empirically practiced and theoretically guided allocation strategies.
- This work also opens several compelling directions for further investigation:
- Can the PEANSC rationale be adapted or replaced by other classical allocation logics, such as proportional fairness, egalitarian equivalence, or marginal-cost schemes, within a multi-objective, multi-intervention framework?
- How might this model be extended to dynamic or repeated decision environments, where group behavior and intervention options evolve over time?
- Can related axiomatic approaches be developed for negotiation-based or crisis-responsive settings, where intervention capacities are themselves endogenously formed through collective mobilization?
These questions offer promising avenues for both theoretical refinement and applied translation, particularly in domains such as strategic resource allocation, pandemic preparedness, and collaborative governance under uncertainty.
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Agent n | Strategy Set | Epidemiological Interpretation of |
---|---|---|
j (testing centre) | : no mass testing; : weekly testing; : daily testing | |
i (vaccination unit) | : no campaign; : single–shot campaign reaching ∼70% coverage | |
k (awareness office) | : no outreach; : continuous risk communication via social media |
Objective t | Measure | Sum | Definition | Uses | Uses | |||
---|---|---|---|---|---|---|---|---|
The UMIE | 5.333 | 4.833 | 8 | Def. 1 | No | No | ||
The 1-WMIE | 5.000 | 5.250 | 8 | Def. 2 | Yes | No | ||
The 2-WMIE | 5.267 | 4.867 | 8 | Def. 2 | No | Yes | ||
The BWMIE | 4.920 | 5.300 | 8 | Def. 2 | Yes | Yes | ||
The IMIE | 6.545 | 5.818 | 8 | Def. 3 | No | No | ||
The UMIE | 6.667 | 6.167 | 12 | Def. 1 | No | No | ||
The 1-WMIE | 5.400 | 5.850 | 0.750 | 12 | Def. 2 | Yes | No | |
The 2-WMIE | 7.000 | 6.000 | 12 | Def. 2 | No | Yes | ||
The BWMIE | 5.800 | 5.700 | 0.500 | 12 | Def. 2 | Yes | Yes | |
The IMIE | 16.800 | 14.400 | 12 | Def. 3 | No | No |
Objective | Measure | Sum | |||
---|---|---|---|---|---|
The UMIE | 5.33 (0.18) | (0.19) | 4.84 (0.17) | 8 | |
The 1-WMIE | 5.00 (0.17) | (0.18) | 5.25 (0.16) | 8 | |
The 2-WMIE | 5.27 (0.18) | (0.19) | 4.86 (0.17) | 8 | |
The BWMIE | 4.92 (0.16) | (0.17) | 5.30 (0.15) | 8 | |
The IMIE | 6.54 (0.22) | (0.23) | 5.82 (0.21) | 8 | |
The UMIE | 6.67 (0.23) | 6.17 (0.24) | (0.20) | 12 | |
The 1-WMIE | 5.40 (0.21) | 5.85 (0.22) | 0.75 (0.18) | 12 | |
The 2-WMIE | 7.00 (0.24) | 6.00 (0.25) | (0.21) | 12 | |
The BWMIE | 5.80 (0.20) | 5.70 (0.21) | 0.50 (0.17) | 12 | |
The IMIE | 16.80 (0.55) | 14.40 (0.53) | (0.60) | 12 |
Agent n | Strategy Set | Epidemiological Interpretation () |
---|---|---|
j (testing centre) | : no mass testing; : weekly screening; : daily screening | |
i (vaccination unit) | : no campaign; : single-shot campaign reaching ≈70% coverage | |
k (risk-communication) | : no outreach; : continuous social-media messaging | |
ℓ (contact tracing) | : no tracing; : manual tracing within 48 h; : digital tracing with 24 h follow-up | |
q (logistics/PPE) | : no PPE stockpile; : 4-week buffer; : 8-week buffer plus rapid deployment hubs |
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Huang, J.-C.; Chen, K.H.-C.; Liao, Y.-H. Resource Allocation in Multi-Objective Epidemic Management: An Axiomatic Analysis. Mathematics 2025, 13, 2182. https://doi.org/10.3390/math13132182
Huang J-C, Chen KH-C, Liao Y-H. Resource Allocation in Multi-Objective Epidemic Management: An Axiomatic Analysis. Mathematics. 2025; 13(13):2182. https://doi.org/10.3390/math13132182
Chicago/Turabian StyleHuang, Jong-Chin, Kelvin H.-C. Chen, and Yu-Hsien Liao. 2025. "Resource Allocation in Multi-Objective Epidemic Management: An Axiomatic Analysis" Mathematics 13, no. 13: 2182. https://doi.org/10.3390/math13132182
APA StyleHuang, J.-C., Chen, K. H.-C., & Liao, Y.-H. (2025). Resource Allocation in Multi-Objective Epidemic Management: An Axiomatic Analysis. Mathematics, 13(13), 2182. https://doi.org/10.3390/math13132182