Next Article in Journal
The Effect of Granular Commercial Fertilizers Containing Elemental Sulfur on Wheat Yield under Mediterranean Conditions
Previous Article in Journal
Translating Flowering Time from Arabidopsis thaliana to Brassicaceae and Asteraceae Crop Species
Open AccessArticle

Phytochemistry of Three Ecuadorian Lamiaceae: Lepechinia heteromorpha (Briq.) Epling, Lepechinia radula (Benth.) Epling and Lepechinia paniculata (Kunth) Epling

1
Departamento de Química y Ciencias Exactas, Universidad Técnica Particular de Loja (UTPL), Calle M. Champagnat s/n, 1101608 Loja, Ecuador
2
Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, Via P. Giuria 9, 10125 Torino, Italy
*
Author to whom correspondence should be addressed.
Received: 27 November 2018 / Revised: 11 December 2018 / Accepted: 15 December 2018 / Published: 20 December 2018
(This article belongs to the Section Phytochemistry)
In this research, the leaves of Lepechinia heteromorpha (Briq.) Epling, Lepechinia radula (Benth.) Epling and Lepechinia paniculata (Kunth) Epling have been collected in order to perform a phytochemical study. The first species was distilled to obtain a novel essential oil (EO), while the others were submitted to ethyl acetate extraction and secondary metabolite isolation. The chemical composition of the EO from L. heteromorpha has been investigated by Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography with Retention Indices (GC(RI)), identifying 25 constituents. A major compound, (−)-ledol (21.2%), and a minor compound, (−)-caryophyllene oxide (1.0%), were isolated from the EO and their structures confirmed by Nuclear Magnetic Resonance (NMR) spectroscopy. Other major constituents of the EO were viridiflorene (27.3%), (E,E)-α-farnesene (1.4%), spirolepechinene and (E)-β-caryophyllene (7.1% each), allo-aromadendrene (6.1%), camphor (1.7%), limonene (1.3%) and β-phellandrene (4.6%). The enantiomeric composition of the EO monoterpene fraction was also studied, determining the enantiomeric excess and distribution of α-pinene, limonene, β-phellandrene and camphor. The ethyl acetate extract of L. radula and L. paniculata were fractionated by column chromatography. Spathulenol, angustanoic acid E and 5-hydroxy-4′,7-dimethoxy flavone were isolated from L. radula extract; ledol, guaiol and (−)-carnosol were found in L. paniculata. View Full-Text
Keywords: Ecuador; Lamiaceae; essential oil; ledol; caryophyllene oxide; spathulenol; angustanoic acid E; 5-hydroxy-4′,7-dimethoxy flavone; guaiol; carnosol Ecuador; Lamiaceae; essential oil; ledol; caryophyllene oxide; spathulenol; angustanoic acid E; 5-hydroxy-4′,7-dimethoxy flavone; guaiol; carnosol
Show Figures

Figure 1

MDPI and ACS Style

Gilardoni, G.; Ramírez, J.; Montalván, M.; Quinche, W.; León, J.; Benítez, L.; Morocho, V.; Cumbicus, N.; Bicchi, C. Phytochemistry of Three Ecuadorian Lamiaceae: Lepechinia heteromorpha (Briq.) Epling, Lepechinia radula (Benth.) Epling and Lepechinia paniculata (Kunth) Epling. Plants 2019, 8, 1.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop