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Plants 2018, 7(4), 105;

Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz

Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, 22390 Tijuana, Mexico
Departamento de Química Analítica, Facultad de Medicina, Universidad Autónoma de Nuevo León, Madero y Dr. Aguirre Pequeño, 64460 Monterrey, Mexico
Centro de Investigación Científica y Educación Superior de Ensenada (CICESE), Carretera Tijuana-Ensenada 3918, 22860 Ensenada, Mexico
Facultad de Ciencias, Universidad Autónoma de Baja California, Carretera Tijuana-Ensenada km. 103, 22860 Ensenada, Mexico
Instituto Universitario de Bio-Orgánica “Antonio González”, Universidad de La Laguna, Avenida Astrofísico Francisco Sánchez 2, 38206 La Laguna, Spain
Authors to whom correspondence should be addressed.
Received: 18 October 2018 / Revised: 13 November 2018 / Accepted: 18 November 2018 / Published: 23 November 2018
(This article belongs to the Special Issue Lamiaceae Species: Biology, Ecology and Practical Uses)
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The antioxidant, antimicrobial, antiproliferative, and enzyme inhibitory properties of five extracts from aerial parts of Salvia pachyphylla Epling ex Munz were examined to assess the prospective of this plant as a source of natural products with therapeutic potential. These properties were analyzed by performing a set of standard assays. The extract obtained with dichloromethane showed the most variety of components, as they yielded promising results in all completed assays. Furthermore, the extract obtained with ethyl acetate exhibited the greatest antioxidant activity, as well as the best xanthine oxidase inhibitory activity. Remarkably, both extracts obtained with n-hexane or dichloromethane revealed significant antimicrobial activity against the Gram-positive bacteria; additionally, they showed greater antiproliferative activity against three representative cell lines of the most common types of cancers in women worldwide, and against a cell line that exemplifies cancers that typically develop drug resistance. Despite that, other extracts were less active, such as the methanolic or aqueous; their results are promising for the isolation and identification of novel bioactive molecules. View Full-Text
Keywords: Salvia pachyphylla; plant extracts; antioxidant; antimicrobial; antiproliferative; enzyme inhibitory Salvia pachyphylla; plant extracts; antioxidant; antimicrobial; antiproliferative; enzyme inhibitory

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Almada-Taylor, G.; Díaz-Rubio, L.; Salazar-Aranda, R.; Waksman de Torres, N.; Uranga-Solis, C.; Delgadillo-Rodríguez, J.; Ramos, M.A.; Padrón, J.M.; Hernández-Martínez, R.; Córdova-Guerrero, I. Biological Activities of Extracts from Aerial Parts of Salvia pachyphylla Epling Ex Munz. Plants 2018, 7, 105.

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