Next Article in Journal
Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors
Next Article in Special Issue
What Happened to the Phycobilisome?
Previous Article in Journal
Changes in Mitochondrial Genome Associated with Predisposition to Atherosclerosis and Related Disease
Previous Article in Special Issue
Metabolic Innovations Underpinning the Origin and Diversification of the Diatom Chloroplast
Open AccessReview

There Is Treasure Everywhere: Reductive Plastid Evolution in Apicomplexa in Light of Their Close Relatives

Institute of Parasitology, Biology Centre Czech Acad. Sci., České Budějovice 370 05, Czech Republic
*
Authors to whom correspondence should be addressed.
Biomolecules 2019, 9(8), 378; https://doi.org/10.3390/biom9080378
Received: 16 July 2019 / Revised: 16 August 2019 / Accepted: 16 August 2019 / Published: 19 August 2019
(This article belongs to the Special Issue Evolutionary and Molecular Aspects of Plastid Endosymbioses)
The phylum Apicomplexa (Alveolates) comprises a group of host-associated protists, predominately intracellular parasites, including devastating parasites like Plasmodium falciparum, the causative agent of malaria. One of the more fascinating characteristics of Apicomplexa is their highly reduced (and occasionally lost) remnant plastid, termed the apicoplast. Four core metabolic pathways are retained in the apicoplast: heme synthesis, iron–sulfur cluster synthesis, isoprenoid synthesis, and fatty acid synthesis. It has been suggested that one or more of these pathways are essential for plastid and plastid genome retention. The past decade has witnessed the discovery of several apicomplexan relatives, and next-generation sequencing efforts are revealing that they retain variable plastid metabolic capacities. These data are providing clues about the core genes and pathways of reduced plastids, while at the same time further confounding our view on the evolutionary history of the apicoplast. Here, we examine the evolutionary history of the apicoplast, explore plastid metabolism in Apicomplexa and their close relatives, and propose that the differences among reduced plastids result from a game of endosymbiotic roulette. Continued exploration of the Apicomplexa and their relatives is sure to provide new insights into the evolution of the apicoplast and apicomplexans as a whole. View Full-Text
Keywords: apicoplast; Chromerid; Apicomplexa; Corallicolids; plastid reduction apicoplast; Chromerid; Apicomplexa; Corallicolids; plastid reduction
Show Figures

Figure 1

MDPI and ACS Style

Salomaki, E.D.; Kolisko, M. There Is Treasure Everywhere: Reductive Plastid Evolution in Apicomplexa in Light of Their Close Relatives. Biomolecules 2019, 9, 378.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop