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Antidiabetic Potential of Medicinal Plants and Their Active Components

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Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran
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Department of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, MB R3B 2G3, Canada
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Department of Chemistry, Manipal Institute of Technology, Manipal University, Manipal 576104, India
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Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Rudaki 139, Dushanbe 734003, Tajikistan
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Department of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepción 4070386, Chile
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Facultad de Educación y Ciencias Sociales, Universidad Andrés Bello, Autopista Concepción—Talcahuano, Concepción 7100, Chile
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Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran 1991953381, Iran
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Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran 11369, Iran
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Department of Biochemistry, Faculty of Science, University of Yaounde 1, Yaounde P.O. Box 812, Cameroon
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Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran 11369, Iran
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Laboratory of Halal Science Research, Halal Products Research Institute, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia
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Integrative Pharmacogenomics Institute (iPROMISE), Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam Campus, Bandar Puncak Alam Selangor 42300, Malaysia
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Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy
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Universidad de Concepción, Unidad de Desarrollo Tecnológico, UDT, Concepción 4070386, Chile
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Research Group on Community Nutrition and Oxidative Stress, Laboratory of Physical Activity Sciences, and CIBEROBN—Physiopathology of Obesity and Nutrition, CB12/03/30038, University of Balearic Islands, E-07122 Palma de Mallorca, Spain
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Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA
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CREA—Research Centre for Food and Nutrition, Via Ardeatina 546, 00178 Rome, Italy
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Department of Pharmacy, University of Napoli Federico II, Via D. Montesano, 49-80131 Napoli, Italy
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Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy
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Medical Illustration, Kendall College of Art and Design, Ferris State University, Grand Rapids, MI 49503, USA
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H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
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Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong, China
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Department of Pharmacology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft 7861756447, Iran
*
Authors to whom correspondence should be addressed.
Biomolecules 2019, 9(10), 551; https://doi.org/10.3390/biom9100551
Received: 29 August 2019 / Revised: 17 September 2019 / Accepted: 25 September 2019 / Published: 30 September 2019
Diabetes mellitus is one of the major health problems in the world, the incidence and associated mortality are increasing. Inadequate regulation of the blood sugar imposes serious consequences for health. Conventional antidiabetic drugs are effective, however, also with unavoidable side effects. On the other hand, medicinal plants may act as an alternative source of antidiabetic agents. Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies. The beneficial potential of each plant matrix is given by the combined and concerted action of their profile of biologically active compounds. View Full-Text
Keywords: Diabetes mellitus; medicinal plants; antidiabetic; hypoglycemic; antihyperglycemic Diabetes mellitus; medicinal plants; antidiabetic; hypoglycemic; antihyperglycemic
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MDPI and ACS Style

Salehi, B.; Ata, A.; V. Anil Kumar, N.; Sharopov, F.; Ramírez-Alarcón, K.; Ruiz-Ortega, A.; Abdulmajid Ayatollahi, S.; Valere Tsouh Fokou, P.; Kobarfard, F.; Amiruddin Zakaria, Z.; Iriti, M.; Taheri, Y.; Martorell, M.; Sureda, A.; N. Setzer, W.; Durazzo, A.; Lucarini, M.; Santini, A.; Capasso, R.; Adrian Ostrander, E.; -ur-Rahman, A.; Iqbal Choudhary, M.; C. Cho, W.; Sharifi-Rad, J. Antidiabetic Potential of Medicinal Plants and Their Active Components. Biomolecules 2019, 9, 551.

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