Role of Uric Acid in Semen
Abstract
:1. Introduction
2. Uric Acid as a Component of Semen
3. The Antioxidant Activity of Uric Acid in Semen
4. Effect of Uric Acid on Sperm Parameters
5. Mechanistic Studies
6. Conclusions and Future Perspectives
Funding
Acknowledgments
Conflicts of Interest
References
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Affecter | Type of Study | Study Population/Sample | Effect on Sperm Parameters | Ref. |
---|---|---|---|---|
Uric acid | In vitro | Human sperm | (+) Sperm motility | [4] |
Urate at 400 µM | In vitro | Human sperm | (−) X-ray-induced sperm DNA damage | [24] |
(+) Seminal uric acid | Observational | Human semen and sperm | (+) Sperm motility (+) Sperm morphology (±) Sperm concentration (±) Semen pH (±) Semen volume | [25] |
Uric acid at (0.25, 0.5/5–7 × 107 cells mL−1) | In vitro | Brown trout semen | (+) Sperm membrane integrity (+) Sperm motility (−) Sperm lipid peroxidation | [16] |
(+) Seminal uric acid | Observational | Sub-fertile men | (±) Semen volume (±) Sperm count (±) Sperm motility | [26] |
Uric acid at 0.25 mmol L−1 | In vitro | Cryopreservation extenders of rainbow trout | (+) Sperm motility | [27] |
(+) Seminal uric acid | Observational | Human semen | (+) Sperm concentration | [28] |
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Banihani, S.A. Role of Uric Acid in Semen. Biomolecules 2018, 8, 65. https://doi.org/10.3390/biom8030065
Banihani SA. Role of Uric Acid in Semen. Biomolecules. 2018; 8(3):65. https://doi.org/10.3390/biom8030065
Chicago/Turabian StyleBanihani, Saleem Ali. 2018. "Role of Uric Acid in Semen" Biomolecules 8, no. 3: 65. https://doi.org/10.3390/biom8030065